1
CELL PHYS Quizzes and Exams Questions
with 100% Correct Answers Latest Versions
2025 Graded A+
What is a typical value for the concentration of Na+ in plasma
in mEq/L
140 (between 134-151)
What is a typical value for the concentration of Ca2+ in
cytosol of a typical mammalian cell at rest (in mEq/L)
0.0002 (between 0.0001-0.0003)
What is a typical value for plasma pH
7.4 (between 7.34-7.46)
What is a distinct difference between facilitated diffusion and
active transport
Active transport generates a solute gradient whereas facilitated
diffusion dissipates a solute gradient
What is true regarding sodium glucose cotransporter in
apical membrane of intestinal epithelial cells (SGLT2)
Facilitated diffusion for Na+, secondary active transport for
glucose, it is a symporter, Na+K+ATPase generates the gradient
that allows SGLT1 to function
An experiment is conducted to determine the relative
permeability of selected solutes to cross an artificial
phospholipid bilayer. To which aqueous solute is the
membrane likely to be most permeant
Oxygen O2 (small non polar molecules)
Charged solutes distribute across a selectively permeable
membrane based upon their concentration gradient and
electrical gradient true or false
,2
True
Calculate a typical value for the Nernst potential in mV for K+
across a typical mammalian cell membrane.
-74 - -96 mV
Calculate a typical value for the Nernst potential in mV for
Ca2+ across a typical mammalian cell membrane.
100-140 mV
If the membrane potential of a cell is -55mV and a Na+
selective channel is opened will Na+ tend to enter or leave
the cell
Enter
An artificial cell has typical cytosolic and extracellular ion
concentrations. Further the cell has a very low number of K+
channels in the cell membrane but no detectable Na+ of Cl-
channels. Calculate the membrane potential for this cell
report the value in mV
-74 - -96 mV
At the peak of a typical action potential to what ion is the
membrane most permeant
Na+
You start with a large beaker of 100mL of HCl with a pH of
2.0. Youn add 900 mL of water to the beaker. After this
dilution what is the pH of the HCl solution
3 (between 2.98 and 3.02)
Your canine patient is given warfarin (weak acid, pKa 5.0)
following distribution throughout the body which body fluid
is likely to have the highest concentration of warfarin
Pancreatic secretions
What is the molar concentration of pure water
55.56 (55.5-55.6)
,3
A friend goes to a restaurant and orders a one liter glass of
tea, which has an osmolality of about 20 milliosmoles per
liter. You gasp as she adds six teaspoons of sugar (glucose;
15 grams per teaspoon) to the tea, which word describes her
sweet tea
Hypertonic
Which cytoskeletal filament resists compression forces in
cells
Microtubules
A drug prevents GTP hydrolysis by beta-tubulin. What will
happen to microtubules
Excess stabilization
A treated with Taxol develops peripheral neuropathy. This is
most likely because
Microtubule stability disrupts axonal transport
Which cytoskeletal dysfunction would most impair immune
cell migration to infection sites
Actin dysregulation
Which direction do kinesins generally move cargo along
microtubules
Toward + end of
Which cytoskeletal element is primarily composed of fibrous
proteins twisted into rope-like structures
Intermediate filaments
Which adhesion defect is most associated with blistering
skin disease
Desmosomal cadherin mutation
Why do desmosomes provide stronger tissue integrity than
adherens junctions?
They use intermediate filaments
Which best explains leukocyte rolling along endothelium
, 4
Selectin-carbohydrate weak binding
Inflammatory cytokines increase intestinal permeability in
IBD. Which junction is most involved
tight junction
A patient with mutations in connexins would most likely
present with defects in
Communication between cells
Which adhesion protein is calcium-dependent and
hemophilic
Cadherin
Which junction connects actin filaments across adjacent
cells
Adherens junction
Which cadherin-based junction connects intermediate
filaments between cells
desmosome
Which best explains why vitamin c deficiency causes scurvy
decreased collagen synthesis
A mutation in elation is most likely to affect which organ
Skin
How do glycosaminoglycans contribute to ECM hydration
They carry negative charges that attract water
Why does cartilage act like a "stiff water balloon"
Abundant hydrated GAGs
Which ECM molecules connect collagen and GAGs to
integrins?
laminin and fibronectin
Why are hemidesmosomes especially important in skin
epithelium
They connect intermediate filaments to ECM
CELL PHYS Quizzes and Exams Questions
with 100% Correct Answers Latest Versions
2025 Graded A+
What is a typical value for the concentration of Na+ in plasma
in mEq/L
140 (between 134-151)
What is a typical value for the concentration of Ca2+ in
cytosol of a typical mammalian cell at rest (in mEq/L)
0.0002 (between 0.0001-0.0003)
What is a typical value for plasma pH
7.4 (between 7.34-7.46)
What is a distinct difference between facilitated diffusion and
active transport
Active transport generates a solute gradient whereas facilitated
diffusion dissipates a solute gradient
What is true regarding sodium glucose cotransporter in
apical membrane of intestinal epithelial cells (SGLT2)
Facilitated diffusion for Na+, secondary active transport for
glucose, it is a symporter, Na+K+ATPase generates the gradient
that allows SGLT1 to function
An experiment is conducted to determine the relative
permeability of selected solutes to cross an artificial
phospholipid bilayer. To which aqueous solute is the
membrane likely to be most permeant
Oxygen O2 (small non polar molecules)
Charged solutes distribute across a selectively permeable
membrane based upon their concentration gradient and
electrical gradient true or false
,2
True
Calculate a typical value for the Nernst potential in mV for K+
across a typical mammalian cell membrane.
-74 - -96 mV
Calculate a typical value for the Nernst potential in mV for
Ca2+ across a typical mammalian cell membrane.
100-140 mV
If the membrane potential of a cell is -55mV and a Na+
selective channel is opened will Na+ tend to enter or leave
the cell
Enter
An artificial cell has typical cytosolic and extracellular ion
concentrations. Further the cell has a very low number of K+
channels in the cell membrane but no detectable Na+ of Cl-
channels. Calculate the membrane potential for this cell
report the value in mV
-74 - -96 mV
At the peak of a typical action potential to what ion is the
membrane most permeant
Na+
You start with a large beaker of 100mL of HCl with a pH of
2.0. Youn add 900 mL of water to the beaker. After this
dilution what is the pH of the HCl solution
3 (between 2.98 and 3.02)
Your canine patient is given warfarin (weak acid, pKa 5.0)
following distribution throughout the body which body fluid
is likely to have the highest concentration of warfarin
Pancreatic secretions
What is the molar concentration of pure water
55.56 (55.5-55.6)
,3
A friend goes to a restaurant and orders a one liter glass of
tea, which has an osmolality of about 20 milliosmoles per
liter. You gasp as she adds six teaspoons of sugar (glucose;
15 grams per teaspoon) to the tea, which word describes her
sweet tea
Hypertonic
Which cytoskeletal filament resists compression forces in
cells
Microtubules
A drug prevents GTP hydrolysis by beta-tubulin. What will
happen to microtubules
Excess stabilization
A treated with Taxol develops peripheral neuropathy. This is
most likely because
Microtubule stability disrupts axonal transport
Which cytoskeletal dysfunction would most impair immune
cell migration to infection sites
Actin dysregulation
Which direction do kinesins generally move cargo along
microtubules
Toward + end of
Which cytoskeletal element is primarily composed of fibrous
proteins twisted into rope-like structures
Intermediate filaments
Which adhesion defect is most associated with blistering
skin disease
Desmosomal cadherin mutation
Why do desmosomes provide stronger tissue integrity than
adherens junctions?
They use intermediate filaments
Which best explains leukocyte rolling along endothelium
, 4
Selectin-carbohydrate weak binding
Inflammatory cytokines increase intestinal permeability in
IBD. Which junction is most involved
tight junction
A patient with mutations in connexins would most likely
present with defects in
Communication between cells
Which adhesion protein is calcium-dependent and
hemophilic
Cadherin
Which junction connects actin filaments across adjacent
cells
Adherens junction
Which cadherin-based junction connects intermediate
filaments between cells
desmosome
Which best explains why vitamin c deficiency causes scurvy
decreased collagen synthesis
A mutation in elation is most likely to affect which organ
Skin
How do glycosaminoglycans contribute to ECM hydration
They carry negative charges that attract water
Why does cartilage act like a "stiff water balloon"
Abundant hydrated GAGs
Which ECM molecules connect collagen and GAGs to
integrins?
laminin and fibronectin
Why are hemidesmosomes especially important in skin
epithelium
They connect intermediate filaments to ECM
