Stuvia.com ff- ffThe ffMarketplace ffto ffBuy ffand ffSell ffyour ffStudy ffMaterial
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
ff ff ff f ff ff ff f f m
By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Com
f f ff ff ff ff ff ff ff ff ff
plete
ff
,Test f f Bank f f For Basic f f Pharma c o l ogy foTrhmeNMuarsrkeestmp1la9ctehmtoEBduityiffand f f Sell f f your f f Study 3
Clayton’s Material
Chapter 01: Drug Definitions, Standards, and Information Sources
f f f f f f f f f f f f f f
Willihnga nz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
f f ff f f f f f f f f f f f f f f
MULTIPLE
CHOICE
f f
Which name identifies a drug listed by the US Food
ff ff ff ff ff ff ff ff ff
a nd Drug Administration (FDA)?
ff ff ff ff ff
Brand
Nonproprietary
Official
Trademark
ANS: C ff
The official name is the name under which a drug is
ff ff ff ff f f ff ff ff ff ff
listed by the FDA. The brand name, or trademark, is the
ff ff ff ff ff ff ff ff ff ff ff
name given to a drug by its manufacturer. The
ff ff ff ff ff ff ff ff f f
nonproprietary, o r generic, name is provided by the
ff ff ff ff ff ff ff ff ff
United States Adopted Names Council.
ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 9 ff ff f f ff
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Ca
ff ff ff ff ff ff ff ff
re Environment TOP: Nursing Process Step: Assessment
ff f f f f f f f f f f f f
CON:
Patient Education f f
2. Which source contains information specific to nutritional supplements?
ff ff ff ff ff ff ff
a. USP Dictionary of USAN &International Drug Names
ff ff ff ff f ff ff
b. Natural Medicines Comprehensive Database ff ff ff
c. United States Pharmacopoeia/National Formulary (USP NF)
ff ff ff ff ff
d. DrugmInteraction Facts ff
ANS: C ff
United States Pharmacopoeia/National Formulary contains information specific to
ff ff ff ff ff ff ff
nutrition al supplements. USP Dictionary of USAN & International Drug Names is a
ff ff ff ff ff ff ff ff ff ff ff ff ff
compilation of drug names, pronunciation guide, and possible future FDA approved drugs;
ff ff ff ff ff ff ff ff ff ff ff ff
it does not incl ude nutritional supplements. Natural Medicines Comprehensive Database
ff ff ff ff ff ff ff ff ff ff ff
contains
ff
evidence-
based information on herbal medicines and herbal combination products; it does not include
ff ff ff ff ff ff ff ff ff ff ff ff
information specific to nutritional supplements. Drug Interaction Facts contains comprehe
ff ff ff ff ff ff ff ff ff ff
nsive information on drug interaction facts; it does not include nutritional supplements.
ff ff ff ff ff ff ff ff ff ff ff ff
DIF: f f Cognitive Level: Knowledge REF: p. 4
f f f f ff f f ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Int
ff ff f f ff ff ff ff ff
egrity
TOP: f f f f Nursing Process Step: Assessment ff f f f f f f CON: f f Nutrition | Patient Education ff ff f f
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
ff ff ff ff ff ff ff ff ff ff ff ff ff
a. DrugmFacts and Comparisons ff ff
, Stuvia.com ff- ffThe ffMarketplace ffto ffBuy ffand ffSell ffyour ffStudy
Material
b. Drug Interaction Facts ff ff
c. Handbook on Injectable Drugs ff ff ff
d. Martindale—The Complete Drug Reference f ff ff
ANS: A f f
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
ff ff ff ff ff ff ff ff ff ff ff ff
therapeutic class. Monographs are formatted as tables to allow comparison of
ff ff ff ff ff ff ff ff ff ff ff
simil ar products, brand names, manufacturers, cost indices, and available dosage
ff ff ff ff ff ff ff ff ff ff ff
forms Online version is available.
ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ff f f f f ff ff ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity f f ff ff ff ff ff
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical
f f f f ff f f f f f f f f ff ff f f ff ff
Judgment
ff
4. Which drug reference contains monographs about virtually every single-
ff ff ff ff ff ff ff ff
entity drug available in the United States and describes therapeutic uses of drugs,
ff ff ff ff ff ff ff ff ff ff ff ff
includin g approved and unapproved uses?
ff ff ff ff ff ff
a. Martindale: The Complete Drug Reference ff ff ff ff
b. AHFS Drug Information ff ff
c. Drug Reference ff
d. Drug Facts and Comparisons ff ff ff
ANS: B f f
AHFS Drug Information contains monographs about virtually every single-
ff ff ff ff ff ff ff ff
entity drug available in the United States and describes therapeutic uses of drugs,
ff ff ff ff ff ff ff ff ff ff ff ff
including approved and unapproved uses.
ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ff f f f f ff ff ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity f f ff ff ff ff ff
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
ff f f ff f f ff f f ff ff f f ff ff ff
5. Which online drug reference makes available to healthcare providers and the public a
ff ff ff ff ff ff ff ff ff ff ff ff
st andard, comprehensive, up-to-date look up and downloadable resource about
ff ff ff ff ff ff ff ff ff ff
medicines?
ff
a. American Drug Index ff ff
b. American Hospital Formulary ff ff
c. DailyMed
d. Drug Reference ff
ANS: C ff
DailyMed makes available to healthcare providers and the public a standard, comprehensiv
ff ff ff ff ff ff ff ff ff ff ff
e, up-to-
ff ff
date look up and downloadable resource about medicines. The American Drug Index is
ff ff ff ff ff ff ff ff ff ff ff ff
not appropriate for patient use. The American Hospital Formulary is not appropriate for
ff ff ff ff ff ff ff ff ff ff ff ff ff
patie nt use. The drug reference is not appropriate for patient use.
ff f f ff ff ff ff ff ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 f f f f f f ff ff ff ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Int
ff ff f f ff ff ff ff ff
egrity
TOP: Nursing Process Step: Implementation
f f ff f f ff
CON: Safety | Patient Education | Clinical Judgment
f f ff ff ff ff ff ff
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
ff ff ff ff ff ff ff ff ff ff ff ff ff ff
a. Federal Food, Drug, and Cosmetic Act (1938) ff ff ff ff ff ff
b. Durham Humphrey Amendment (1952) ff ff ff
, Test f f Bank f f For Basic f f Pharma c o l ogy foTrhmeNMuarsrkeestmp1la9ctehmtoEBduityiffand f f Sell f f your f f Study 4
Clayton’s Material
c. Controlled Substances Act (1970) ff ff ff
d. Kefauver Harris Drug Amendment (1962) ff ff ff ff
ANS: A f f
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
ff ff ff ff ff ff ff ff ff f f ff ff ff
the s afety of all drugs before marketing. Later amendments and acts helped tighten FDA
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
control and ensure drug safety. The Durham Humphrey Amendment defines the
ff ff f f ff ff ff ff ff ff f f ff
kinds of drugs th at cannot be used safely without medical supervision and restricts
ff ff f f ff ff ff ff ff f f ff ff ff ff f f
their sale to prescription by a licensed practitioner. The Controlled Substances Act
ff ff ff ff ff ff ff ff ff ff ff ff
addresses only controlled substan ces and their categorization. The Kefauver Harris Drug
ff ff ff ff ff ff ff ff ff ff ff ff
Amendment ensures drug efficacy a nd greater drug safety. Drug manufacturers are
ff ff ff ff ff ff f f ff ff ff ff ff
required to prove to the FDA the effectiven ess of their products before marketing them.
ff f f ff ff ff ff ff ff ff ff ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 5 Table ff ff f f ff ff
l.3 OBJ: 5
ff ff f f
NAT: NCLEX Client Needs Category: Physiological ff ff ff ff ff
Integrit y TOP: Nursing Process Step: Assessment
ff f f f f f f f f f f f f
CON: Safety | Patient Education | Evidence | Health Care Law
f f ff ff f f ff ff f f ff f f f f
7. Which classification does meperidine (Demerol) fall under?
ff ff ff ff ff ff
a. I
b. II
c. III
d. IV
ANS: B f f
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
lead to severe psychological and physical dependence. Schedule I drugs have high
ff ff ff ff ff ff ff ff ff ff ff ff
potential for abuse and no recognized medical use. Schedule III drugs have some
ff ff ff ff ff ff ff ff ff ff ff ff ff
potential for abuse. U se may lead to low to moderate physical dependence or high
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
psychological dependence. Sc hedule IV drugs have low potential for abuse. Use may lead
ff ff ff ff ff ff ff ff ff ff ff ff ff ff
to limited physical or psychol ogical dependence.
ff ff ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 10
f f f f f f ff f f ff
OBJ: 2 NAT: NCLEX Client Needs Category: Safe, Effective
ff ff f f ff ff ff ff ff
C are Environment
ff ff ff
TOP: Nursing Process Step: Assessment CON: Patient Education
f f f f ff f f f f f f f f f f f f | Addiction | Pain
ff ff ff
8. Which action would the FDA take to expedite drug development and approval for an
ff ff ff ff ff ff ff ff ff ff ff ff ff
outbre ak of smallpox?
ff ff ff ff
a. List smallpox as a health orphan disease.
ff ff ff ff ff ff
b. Omit the preclinical research phase. ff ff ff ff
c. Extend the clinical research phase. ff ff ff ff
d. Fast track the investigational drug.ff ff ff ff
ANS: D ff
Once the Investigational New Drug Application has been approved, the drug can receive h
ff ff ff ff ff ff ff ff ff ff ff ff ff
ighest priority within the agency, which is called fast tracking. A smallpox outbreak
ff ff ff ff ff ff ff ff ff ff ff ff ff
would become a priority concern in the world. Orphan diseases are not researched in a
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
priority manner. Preclinical research is not omitted. Extending any phase of the research
ff ff ff ff ff ff ff ff ff ff ff ff ff
would me an a longer time to develop a vaccine. The FDA must ensure that all phases
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
of the preclinic al and clinical research phase have been completed in a safe manner.
ff ff ff ff ff ff ff ff ff ff ff f f ff ff ff
DIF: Cognitive Level: Knowledge ff f f REF: p. 7 f f OBJ: 5 f f
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
ff ff ff f ff ff ff f f m
By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Com
f f ff ff ff ff ff ff ff ff ff
plete
ff
,Test f f Bank f f For Basic f f Pharma c o l ogy foTrhmeNMuarsrkeestmp1la9ctehmtoEBduityiffand f f Sell f f your f f Study 3
Clayton’s Material
Chapter 01: Drug Definitions, Standards, and Information Sources
f f f f f f f f f f f f f f
Willihnga nz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
f f ff f f f f f f f f f f f f f f
MULTIPLE
CHOICE
f f
Which name identifies a drug listed by the US Food
ff ff ff ff ff ff ff ff ff
a nd Drug Administration (FDA)?
ff ff ff ff ff
Brand
Nonproprietary
Official
Trademark
ANS: C ff
The official name is the name under which a drug is
ff ff ff ff f f ff ff ff ff ff
listed by the FDA. The brand name, or trademark, is the
ff ff ff ff ff ff ff ff ff ff ff
name given to a drug by its manufacturer. The
ff ff ff ff ff ff ff ff f f
nonproprietary, o r generic, name is provided by the
ff ff ff ff ff ff ff ff ff
United States Adopted Names Council.
ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 9 ff ff f f ff
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Ca
ff ff ff ff ff ff ff ff
re Environment TOP: Nursing Process Step: Assessment
ff f f f f f f f f f f f f
CON:
Patient Education f f
2. Which source contains information specific to nutritional supplements?
ff ff ff ff ff ff ff
a. USP Dictionary of USAN &International Drug Names
ff ff ff ff f ff ff
b. Natural Medicines Comprehensive Database ff ff ff
c. United States Pharmacopoeia/National Formulary (USP NF)
ff ff ff ff ff
d. DrugmInteraction Facts ff
ANS: C ff
United States Pharmacopoeia/National Formulary contains information specific to
ff ff ff ff ff ff ff
nutrition al supplements. USP Dictionary of USAN & International Drug Names is a
ff ff ff ff ff ff ff ff ff ff ff ff ff
compilation of drug names, pronunciation guide, and possible future FDA approved drugs;
ff ff ff ff ff ff ff ff ff ff ff ff
it does not incl ude nutritional supplements. Natural Medicines Comprehensive Database
ff ff ff ff ff ff ff ff ff ff ff
contains
ff
evidence-
based information on herbal medicines and herbal combination products; it does not include
ff ff ff ff ff ff ff ff ff ff ff ff
information specific to nutritional supplements. Drug Interaction Facts contains comprehe
ff ff ff ff ff ff ff ff ff ff
nsive information on drug interaction facts; it does not include nutritional supplements.
ff ff ff ff ff ff ff ff ff ff ff ff
DIF: f f Cognitive Level: Knowledge REF: p. 4
f f f f ff f f ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Int
ff ff f f ff ff ff ff ff
egrity
TOP: f f f f Nursing Process Step: Assessment ff f f f f f f CON: f f Nutrition | Patient Education ff ff f f
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
ff ff ff ff ff ff ff ff ff ff ff ff ff
a. DrugmFacts and Comparisons ff ff
, Stuvia.com ff- ffThe ffMarketplace ffto ffBuy ffand ffSell ffyour ffStudy
Material
b. Drug Interaction Facts ff ff
c. Handbook on Injectable Drugs ff ff ff
d. Martindale—The Complete Drug Reference f ff ff
ANS: A f f
Drug Facts and Comparisons contains drug monographs that describe all drugs in a
ff ff ff ff ff ff ff ff ff ff ff ff
therapeutic class. Monographs are formatted as tables to allow comparison of
ff ff ff ff ff ff ff ff ff ff ff
simil ar products, brand names, manufacturers, cost indices, and available dosage
ff ff ff ff ff ff ff ff ff ff ff
forms Online version is available.
ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ff f f f f ff ff ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity f f ff ff ff ff ff
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical
f f f f ff f f f f f f f f ff ff f f ff ff
Judgment
ff
4. Which drug reference contains monographs about virtually every single-
ff ff ff ff ff ff ff ff
entity drug available in the United States and describes therapeutic uses of drugs,
ff ff ff ff ff ff ff ff ff ff ff ff
includin g approved and unapproved uses?
ff ff ff ff ff ff
a. Martindale: The Complete Drug Reference ff ff ff ff
b. AHFS Drug Information ff ff
c. Drug Reference ff
d. Drug Facts and Comparisons ff ff ff
ANS: B f f
AHFS Drug Information contains monographs about virtually every single-
ff ff ff ff ff ff ff ff
entity drug available in the United States and describes therapeutic uses of drugs,
ff ff ff ff ff ff ff ff ff ff ff ff
including approved and unapproved uses.
ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 ff f f f f ff ff ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity f f ff ff ff ff ff
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
ff f f ff f f ff f f ff ff f f ff ff ff
5. Which online drug reference makes available to healthcare providers and the public a
ff ff ff ff ff ff ff ff ff ff ff ff
st andard, comprehensive, up-to-date look up and downloadable resource about
ff ff ff ff ff ff ff ff ff ff
medicines?
ff
a. American Drug Index ff ff
b. American Hospital Formulary ff ff
c. DailyMed
d. Drug Reference ff
ANS: C ff
DailyMed makes available to healthcare providers and the public a standard, comprehensiv
ff ff ff ff ff ff ff ff ff ff ff
e, up-to-
ff ff
date look up and downloadable resource about medicines. The American Drug Index is
ff ff ff ff ff ff ff ff ff ff ff ff
not appropriate for patient use. The American Hospital Formulary is not appropriate for
ff ff ff ff ff ff ff ff ff ff ff ff ff
patie nt use. The drug reference is not appropriate for patient use.
ff f f ff ff ff ff ff ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 f f f f f f ff ff ff ff
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Int
ff ff f f ff ff ff ff ff
egrity
TOP: Nursing Process Step: Implementation
f f ff f f ff
CON: Safety | Patient Education | Clinical Judgment
f f ff ff ff ff ff ff
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
ff ff ff ff ff ff ff ff ff ff ff ff ff ff
a. Federal Food, Drug, and Cosmetic Act (1938) ff ff ff ff ff ff
b. Durham Humphrey Amendment (1952) ff ff ff
, Test f f Bank f f For Basic f f Pharma c o l ogy foTrhmeNMuarsrkeestmp1la9ctehmtoEBduityiffand f f Sell f f your f f Study 4
Clayton’s Material
c. Controlled Substances Act (1970) ff ff ff
d. Kefauver Harris Drug Amendment (1962) ff ff ff ff
ANS: A f f
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
ff ff ff ff ff ff ff ff ff f f ff ff ff
the s afety of all drugs before marketing. Later amendments and acts helped tighten FDA
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
control and ensure drug safety. The Durham Humphrey Amendment defines the
ff ff f f ff ff ff ff ff ff f f ff
kinds of drugs th at cannot be used safely without medical supervision and restricts
ff ff f f ff ff ff ff ff f f ff ff ff ff f f
their sale to prescription by a licensed practitioner. The Controlled Substances Act
ff ff ff ff ff ff ff ff ff ff ff ff
addresses only controlled substan ces and their categorization. The Kefauver Harris Drug
ff ff ff ff ff ff ff ff ff ff ff ff
Amendment ensures drug efficacy a nd greater drug safety. Drug manufacturers are
ff ff ff ff ff ff f f ff ff ff ff ff
required to prove to the FDA the effectiven ess of their products before marketing them.
ff f f ff ff ff ff ff ff ff ff ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 5 Table ff ff f f ff ff
l.3 OBJ: 5
ff ff f f
NAT: NCLEX Client Needs Category: Physiological ff ff ff ff ff
Integrit y TOP: Nursing Process Step: Assessment
ff f f f f f f f f f f f f
CON: Safety | Patient Education | Evidence | Health Care Law
f f ff ff f f ff ff f f ff f f f f
7. Which classification does meperidine (Demerol) fall under?
ff ff ff ff ff ff
a. I
b. II
c. III
d. IV
ANS: B f f
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
lead to severe psychological and physical dependence. Schedule I drugs have high
ff ff ff ff ff ff ff ff ff ff ff ff
potential for abuse and no recognized medical use. Schedule III drugs have some
ff ff ff ff ff ff ff ff ff ff ff ff ff
potential for abuse. U se may lead to low to moderate physical dependence or high
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
psychological dependence. Sc hedule IV drugs have low potential for abuse. Use may lead
ff ff ff ff ff ff ff ff ff ff ff ff ff ff
to limited physical or psychol ogical dependence.
ff ff ff ff ff ff ff
DIF: Cognitive Level: Knowledge REF: p. 10
f f f f f f ff f f ff
OBJ: 2 NAT: NCLEX Client Needs Category: Safe, Effective
ff ff f f ff ff ff ff ff
C are Environment
ff ff ff
TOP: Nursing Process Step: Assessment CON: Patient Education
f f f f ff f f f f f f f f f f f f | Addiction | Pain
ff ff ff
8. Which action would the FDA take to expedite drug development and approval for an
ff ff ff ff ff ff ff ff ff ff ff ff ff
outbre ak of smallpox?
ff ff ff ff
a. List smallpox as a health orphan disease.
ff ff ff ff ff ff
b. Omit the preclinical research phase. ff ff ff ff
c. Extend the clinical research phase. ff ff ff ff
d. Fast track the investigational drug.ff ff ff ff
ANS: D ff
Once the Investigational New Drug Application has been approved, the drug can receive h
ff ff ff ff ff ff ff ff ff ff ff ff ff
ighest priority within the agency, which is called fast tracking. A smallpox outbreak
ff ff ff ff ff ff ff ff ff ff ff ff ff
would become a priority concern in the world. Orphan diseases are not researched in a
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
priority manner. Preclinical research is not omitted. Extending any phase of the research
ff ff ff ff ff ff ff ff ff ff ff ff ff
would me an a longer time to develop a vaccine. The FDA must ensure that all phases
ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff ff
of the preclinic al and clinical research phase have been completed in a safe manner.
ff ff ff ff ff ff ff ff ff ff ff f f ff ff ff
DIF: Cognitive Level: Knowledge ff f f REF: p. 7 f f OBJ: 5 f f
