TietzFundamentalsOf
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CLINICAL CHEMISTRY AND
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MOLECULAR DIAGNOSTICS Vl l
7thEditionByCarlA.Burtis
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TEST BANK Vl l l l
,TietzFundamentalsofClinicalChemistryandMolecularDiagnostics7thEditionTestBank
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Tableofcontents: l l
I.PrinciplesOfLaboratoryMedicine
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Chapter1.ClinicalChemistry,MolecularDiagnostics,andLaboratoryMedicine
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Chapter2.SelectionandAnalyticalEvaluationofMethods —WithStatisticalTechniques
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Chapter3.ClinicalEvaluationofMethods
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Chapter4.Evidence-Based LaboratoryMedicine
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Chapter5.EstablishmentandUseofReferenceValues
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Chapter6.SpecimenCollection,Processing,andOtherPreanalyticalVariables
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Chapter7.QualityManagement l l
II.AnalyticalTechniquesAndInstrumentation
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Chapter8.PrinciplesofBasicTechniquesandLaboratorySafety
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Chapter9.OpticalTechniques
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Chapter10.ElectrochemistryandChemicalSensors
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Chapter11.Electrophoresis l l
Chapter12.Chromatography l l
Chapter13.MassSpectrometry
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Chapter14.Enzyme and RateAnalyses
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Chapter15.ImmunochemicalTechniques
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Chapter16 Automation l V
Chapter17.Point-of-CareInstrumentation
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III. Analytes
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Chapter18.AminoAcids,Peptides,and Proteins
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Chapter19.SerumEnzymes l l l
Chapter20.TumorMarkersand CancerGenes
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Chapter21.KidneyFunctionTests —Creatinine,GFR,Urea,andUricAcid
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Chapter22.Carbohydrates l l
Chapter23.Lipids,Lipoproteins,Apolipoproteins,and OtherCardiacRiskFactors
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Chapter24.ElectrolytesandBlood Gases
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Chapter25.Hormones l l
Chapter26. CatecholaminesandSerotonin
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Chapter27. Vitamins,TraceElements,NutritionalAssessment
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Chapter28.Hemoglobin,Iron,and Bilirubin
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Chapter29.PorphyrinsandPorphyrias
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Chapter30.TherapeuticDrugs and TheirManagement
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Chapter31.ClinicalToxicology
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Chapter32. ToxicMetals l l l l
IV. Pathophysiology
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Chapter33.Diabetes l l
,Chapter34. CardiovascularDisease
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Chapter35.KidneyDisease
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Chapter36. PhysiologyandDisordersofWater,Electrolyte,andAcid-BaseMetabolism
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Chapter37. LiverDisease
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Chapter38. Gastrointestinaland Pancreatic Diseases
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Chapter39. Disorders ofBoneandMineralMetabolism
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Chapter40. Disorders ofthePituitaryGland
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Chapter41. DisordersoftheAdrenalCortex
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Chapter42. ThyroidDisorders
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Chapter43. Reproduction-RelatedDisorders
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Chapter44. Pregnancyand PrenatalTesting
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Chapter45. NewbornScreening andInbornErrorsofMetabolism
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Chapter46.Pharmacogenetics
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V. MolecularDiagnostics
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Chapter47.PrinciplesofMolecularBiology
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Chapter48.NucleicAcid Techniques and Applications
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Chapter49.GenomesandNucleicAcidAlterations
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, TietzFundamentalsofClinicalChemistryandMolecularDiagnostics,7eBurtisTestBank l l l l l
Chapter01:ClinicalChemistry,MolecularDiagnostics,andLaboratoryMedicineTest Bank
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MULTIPLECHOICE
1. Anindividualworking in a clinical chemistrylaboratoryismarriedtoa salesrepresentativewho wor
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ksforacompanythatsellschemistrylaboratorysupplies.Whenthelaboratorymanagerrequ ests alis l l l ll V
tof needed supplies,costofsupplies,and vendors,thisindividualonlyrecommendsthe s pouse’sco
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mpanyasthevendor.This isconsideredtobea(n): l V
a. accounting issue. V
b. possibleconflict ofinterest. l
c. maintenanceofconfidentialityissue.
d. problemwithresourceallocation.
ANS: B l
Concernhasbeenraisedovertheinterrelationshipsbetweenpractitionersinthemedicalfield andc omm V ll
ercial suppliersofdrugs,devices,equipment,etc.,tothemedical profession.
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Similarly, relationshipshave been scrutinized between clinical laboratoriansandmanufacturersa nd
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providersof diagnosticequipmentand supplies.TheseconcernsledtheNationalInstitutesofH ealth(
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NIH) in 1995 torequire official institutional reviewoffinancial disclosurebyresearchersan d manag
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ement ofsituations inwhich disclosureindicatespotentialconflictsofinterest. V V l
DIF: 1 REF: Page4-5 l l l OBJ: 6|7 l l V
2. Apatient visitsher physician stating that her prescribed painkiller isnot working to reduce thep ain
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following her recent surgery. Afriendof the patient claims thatthesame painkiller “worked won
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ders” toreduce herpainafterthe samesurgery. The physician states that thedifference inth eeffect
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ofthe drug mightbecausedby
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,which isstudied in pharmacogen l V ll
etics.
a. epidemiology
b. aninherited disease V
c. aconflictofinterest
d. ageneticvariationindrug-metabolizingenzymes
ANS: D l
Pharmacogeneticsisthestudyofthegeneticvariationofdrugmetabolism l l l l between individuals V
.
DIF: 1 REF: Page3 l l l OBJ: 1 l
3. John worksin a molecular diagnosticslaboratoryandreceivesa blood sample thathasthename ofa
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closefriendprintedonthebar- V
coded label. Thegenetictest thatisorderedonthe friend’s sample wouldprovidediagnostic inf or
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mationaboutadisorderthat has a poor prognosis, andthetest isusuallyperformedbyJohn. H easks ll V ll V ll ll
a fellowemployee toanalyze thesample forhim and not divulge the results. This ethical i ssuecon
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cerns:
a. confidentialityofpatient genetic andmedical information. V V
b. aconflict ofinterest. V
c. resourceallocation.
d. diagnosticaccuracy.