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1. MAOIs (monoamine oxidase inhibitors) affect which A. Serotonin, Dopamine,
neurotransmitters? Norepinephrine
A. Serotonin, Dopamine, Norepinephrine
B. Serotonin, GABA, Glutamate
C. Acetylcholine, Dopamine, Norepinephrine
D. Dopamine, GABA, Acetylcholine
2. Which of the following is considered first line treat- A. SSRI
ment for depression?
A. SSRI
B. FGA
C. SNRI
D. MAOI
3. When treating a patient for major depression disorder C. Escitalopram
which medication would the PMHNP consider first?
A. Depakote
B. Selegiline
C. Escitalopram
D. Isocarboxazid
4. Which of the following medication should be consid- C. Fluoxetine
ered for a patient diagnosed with major depressive
disorder who reports "always forgetting to take my
pills"?
A. Mirtazapine
B. Fluvoxamine
C. Fluoxetine
D. Carbemazepine
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5. Which of the following medication has a black box B. Lamotrigine
warning of a life-threatening skin rash?
A. Lithium
B. Lamotrigine
C. Lurasidone
D. Lorazepam
6. Which medication is considered the best tolerated D. Escitalopram
SSRI?
A. Venlafaxine
B. Bupropion
C. Setraline
D. Escitalopram
7. During a 4 week follow up appointment, Rashida, who A. Increase Setraline dose
is prescribed Sertraline 25mg qAM reports slight im-
provement in depression symptoms and tolerating
medication well. Which of the following should the
PMHNP do?
A. Increase Setraline dose
B. Switch to an SNRI
C. Switch to a different SSRI
D. Add Trazodone qHS for sleep.
8. Which medication should be avoided for the 66 year C. Paroxetine
patient diagnosed with major depressive disorder and
anxiety with a reported fall 3 months ago?
A. Citalopram
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B. Setraline
C. Paroxetine
D. Aripiprazole
9. A patient reports upset stomach and diarrhea 3 days B. "Most side effects sub-
after taking new prescription of sertraline. Which of side after 4-5 days. Your
the following is the most appropriate response from body is getting adjusted
the PMHNP? to the increased serotonin
levels".
A. "Start doubling the dose of sertraline and your
symptoms will begin to ease up".
B. "Most side effects subside after 4-5 days. Your body
is getting adjusted to the increased serotonin levels".
C. "Stop taking it immediately and go to the local emer-
gency department".
D. "You must take Sertraline with food, otherwise you
will continue to experience GI symptoms".
10. During a 2 week follow up appointment, the patient B. "It can take up to 6
reports no improvement in depressive symptoms with weeks before you notice
escitalopram. Which of the following statement made improvements of depres-
by the PMHNP is correct? sive symptoms".
A. "Let's discontinue escitalopram and start you on
something stronger".
B. "It can take up to 6 weeks before you notice improve-
ments of depressive symptoms".
C. "I am going to prescibe Trazodone. Take it at night
to help you sleep".
D. "Start taking two pills at a time".
11. Duloxetine effects which two neurotransmitters? A. serotonin and norepi-
nephrine