ELSEVIER Clinical Chemistry Exam Questions
with Verified Solutions 100% Verified
Save
Terms in this set (100)
1. Which of the 1. c. Chylomicrons, low-density lipoprotein(LDL), and
following isconsidered a high-density lipoprotein (HDL) are considered to be
lipid? lipoproteins that transport lipids throughout the body;
a.Chylomicrons cholesterol is classified as a lipid.
b. LDL
c.Cholesterol
d. HDL
2. In the laboratory 2. d. Dextran sulfate precipitates all Apo B-containing
procedure for the lipoproteins (chylomicrons, very-low-density
quantification of HDL, the lipoprotein [VLDL], intermediate density lipoprotein
purpose of the dextran [IDL], and low-density lipoprotein [LDL]) leaving high-
sulfate is to: density lipoprotein (HDL) (Apo A-containing
a. Precipitate all Apo A1 lipoprotein) in the supernatant. HDL is then mixed with
containing lipoproteins the reagent cholesterol esterase and cholesterol
b. Covert cholesterol oxidase to quantitate HDL concentrations.
esters to cholesterol for
detection
c. Precipitate all Apo B
and Apo A containing
lipoproteins
d. Precipitate all Apo B
containing proteins
,3. Which of the following 3. a. Lipoproteins are characterized by size and
lipoproteins is the smallest density. High-density lipoprotein (HDL) is the smallest,
of all the lipoproteins and most dense lipoprotein, carrying 50% of its weight as
is composed of 50% protein.
protein?
a.HDL
b. Chylomicrons
c. LDL
d.Triglycerides
4. Which of the following 4. d. Triglycerides are most adversely affected by
would be most adversely recent food intake, and therefore a fast is always
affected by a non-fasting recommended for triglyceride analysis.
sample?
a.HDL
b. LDL
c.Cholesterol
d.Triglycerides
5. Which of the following 5. c. Apo E is a ligand for the low-density lipoprotein
apoproteins is responsible (LDL) receptor, reverses cholesterol transport, and is
for receptor binding for a regulator of cell growth and immune responses.
IDL and the chylomicron
remnant produced in fat
transport?
a.Apo A1
b.Apo C
c.Apo E
d.Apo B
,6. Which of the following 6. c. Two enzymes are responsible for esterifying
enzymes is found bound cholesterol, lecithin-cholesterol acyl transferase
to HDL and LDL in blood (extracellular), and acetyl coenzyme A (acyl- CoA)
plasma and acts to cholesterol acyltransferase (intracellular).
convert free cholesterol
into cholesteryl esters?
a.Cholesterol esterase
b. Cholesterol oxidase
c. Lecithin-cholesterol
acyltransferase
d. Lipase
7. Which of the following 7. a. Although lipoproteins can be assayed using a
blood samples would variety of anticoagulants, the preferred anticoagulant
serve best to assay is ethylenediaminetetraacetic acid (EDTA) because it
lipoproteins because this preserves lipoproteins over time.
anticoagulant acts to
preserve lipoproteins?
a.EDTA plasma sample
b. Heparin plasma sample
c.Citrate plasma sample
d. Fluoride plasma sample
8. Exogenous triglycerides 8. b. Triglycerides are transported throughout the
are transported in the body by means of two lipoproteins: very-low-density
plasma in which of the lipoprotein (VLDL) and chylomicrons. VLDL carries
following forms? endogenously derived triglycerides, and
a.VLDL chylomicrons carry exogenously derived
b. Chylomicrons triglycerides.
c. LDL
d. Cholesteryl esters
, 9. A patient presents to his 9. b. Low-density lipoprotein (LDL) cholesterol is
physician for a lipid calculated as follows: LDL TC HDL + TG=5 LDL 300 50
profile. The following + 200=5 LDL 300 90 LDL 210 mg=dL
results are received: HDL
50 mg/dL Total cholesterol
300 mg/dL Triglycerides
200 mg/dL The calculated
LDL cholesterol is:
a. 200
b. 210
c. 290
d. 350
10. According to the 10. b. Low-density lipoprotein (LDL) is currently the
National Cholesterol only lipoprotein or lipid that is recommended for use
Education Program, which by physicians for therapeutic lifestyle changes.
lipid or lipoprotein class is
more important for
therapeutic decision
making (diet and
medication decisions)?
a. Chylomicrons
b. LDL
c. HDL
d. Cholesterol
with Verified Solutions 100% Verified
Save
Terms in this set (100)
1. Which of the 1. c. Chylomicrons, low-density lipoprotein(LDL), and
following isconsidered a high-density lipoprotein (HDL) are considered to be
lipid? lipoproteins that transport lipids throughout the body;
a.Chylomicrons cholesterol is classified as a lipid.
b. LDL
c.Cholesterol
d. HDL
2. In the laboratory 2. d. Dextran sulfate precipitates all Apo B-containing
procedure for the lipoproteins (chylomicrons, very-low-density
quantification of HDL, the lipoprotein [VLDL], intermediate density lipoprotein
purpose of the dextran [IDL], and low-density lipoprotein [LDL]) leaving high-
sulfate is to: density lipoprotein (HDL) (Apo A-containing
a. Precipitate all Apo A1 lipoprotein) in the supernatant. HDL is then mixed with
containing lipoproteins the reagent cholesterol esterase and cholesterol
b. Covert cholesterol oxidase to quantitate HDL concentrations.
esters to cholesterol for
detection
c. Precipitate all Apo B
and Apo A containing
lipoproteins
d. Precipitate all Apo B
containing proteins
,3. Which of the following 3. a. Lipoproteins are characterized by size and
lipoproteins is the smallest density. High-density lipoprotein (HDL) is the smallest,
of all the lipoproteins and most dense lipoprotein, carrying 50% of its weight as
is composed of 50% protein.
protein?
a.HDL
b. Chylomicrons
c. LDL
d.Triglycerides
4. Which of the following 4. d. Triglycerides are most adversely affected by
would be most adversely recent food intake, and therefore a fast is always
affected by a non-fasting recommended for triglyceride analysis.
sample?
a.HDL
b. LDL
c.Cholesterol
d.Triglycerides
5. Which of the following 5. c. Apo E is a ligand for the low-density lipoprotein
apoproteins is responsible (LDL) receptor, reverses cholesterol transport, and is
for receptor binding for a regulator of cell growth and immune responses.
IDL and the chylomicron
remnant produced in fat
transport?
a.Apo A1
b.Apo C
c.Apo E
d.Apo B
,6. Which of the following 6. c. Two enzymes are responsible for esterifying
enzymes is found bound cholesterol, lecithin-cholesterol acyl transferase
to HDL and LDL in blood (extracellular), and acetyl coenzyme A (acyl- CoA)
plasma and acts to cholesterol acyltransferase (intracellular).
convert free cholesterol
into cholesteryl esters?
a.Cholesterol esterase
b. Cholesterol oxidase
c. Lecithin-cholesterol
acyltransferase
d. Lipase
7. Which of the following 7. a. Although lipoproteins can be assayed using a
blood samples would variety of anticoagulants, the preferred anticoagulant
serve best to assay is ethylenediaminetetraacetic acid (EDTA) because it
lipoproteins because this preserves lipoproteins over time.
anticoagulant acts to
preserve lipoproteins?
a.EDTA plasma sample
b. Heparin plasma sample
c.Citrate plasma sample
d. Fluoride plasma sample
8. Exogenous triglycerides 8. b. Triglycerides are transported throughout the
are transported in the body by means of two lipoproteins: very-low-density
plasma in which of the lipoprotein (VLDL) and chylomicrons. VLDL carries
following forms? endogenously derived triglycerides, and
a.VLDL chylomicrons carry exogenously derived
b. Chylomicrons triglycerides.
c. LDL
d. Cholesteryl esters
, 9. A patient presents to his 9. b. Low-density lipoprotein (LDL) cholesterol is
physician for a lipid calculated as follows: LDL TC HDL + TG=5 LDL 300 50
profile. The following + 200=5 LDL 300 90 LDL 210 mg=dL
results are received: HDL
50 mg/dL Total cholesterol
300 mg/dL Triglycerides
200 mg/dL The calculated
LDL cholesterol is:
a. 200
b. 210
c. 290
d. 350
10. According to the 10. b. Low-density lipoprotein (LDL) is currently the
National Cholesterol only lipoprotein or lipid that is recommended for use
Education Program, which by physicians for therapeutic lifestyle changes.
lipid or lipoprotein class is
more important for
therapeutic decision
making (diet and
medication decisions)?
a. Chylomicrons
b. LDL
c. HDL
d. Cholesterol
