KUBY IMMUNOLOGY EXAM 2 QUESTIONS AND ANSWERS

KUBY IMMUNOLOGY EXAM 2
QUESTIONS AND ANSWERS



TLR1 Ligands - Correct Answers -Triacyl lipopeptides

TLR2 Ligands - Correct Answers -Peptidoglycans, GPI-linked proteins, lipoproteins,
zymosan

TLR3 Ligands - Correct Answers -dsRNA

TLR4 Ligands - Correct Answers -LPS, F-protein, mannans

TLR5 Ligands - Correct Answers -Flagellin

TLR6 Ligands - Correct Answers -Diacyl lipopeptides, zymosan

TLR7 and TLR8 Ligands - Correct Answers -ssRNA

TLR9 Ligands - Correct Answers -CpG unmethylated dinucleotides, dinucleotides,
herpes virus components, hemozin

TLR11 Ligands - Correct Answers -Profilin

E - Correct Answers -11. Which of the following is NOT usually induced in response to
TLR signaling?

A. TNF-α
B. IL-1
C. iNOS
D. IL-6
E. IL-4

B - Correct Answers -Where would you MOST likely find a TLR that recognizes RNA?

A. On the cell surface
B. In the endosome/lysosome
C. In the nucleus
D. In the mitochondria
E. In the endoplasmic reticulum