KUBY IMMUNOLOGY CHAPTER 1-4
EXAM QUESTIONS AND ANSWERS
Which of the following generally does not apply to bone marrow (a primary lymphoid
organ) and secondary lymphoid organs?
A) cellular proliferation
B) differentiation of lymphocytes
C) cellular interaction
D) antigen-dependent response
E) None of the above. - Correct Answers -D
Which of the following apply uniquely to secondary lymphoid organs?
A) presence of precursor B and T cells
B) circulation of lymphocytes
C) terminal differentiation
D) cellular proliferation
E) All of the above. - Correct Answers -C
Which of the following does not apply to "innate" immune mechanisms?
A) absence of specificity
B) activation by a stimulus
C) involvement of multiple cell types
D) a memory component - Correct Answers -D
Which of the following is the major function of the lymphoid system?
A) innate immunity
B) inflammation
C) phagocytosis
D) acquired immunity
E) None of the above. - Correct Answers -D
Removal of the bursa of Fabricius from a chicken results in
A) a markedly decreased number of circulating T lymphocytes.
B) anemia.
, C) delayed rejection of skin graft.
D) low serum levels of antibodies in serum.
E) all of the above.
F) none of the above. - Correct Answers -D
The germinal centers found in the cortical region of lymph nodes and the peripheral
region of splenic periarteriolar lymphatic tissue
A) support the development of immature B and T cells.
B) function in the removal of damaged erythrocytes from the circulation.
C) act as the major source of stem cells and thus help to maintain hematopoiesis.
D) provide an infrastructure that on antigenic stimulation contains large populations of B
lymphocytes and plasma cells.
E) are the sites of NK-cell differentiation. - Correct Answers -D
Which of the following is correct?
A) NK cells proliferate in response to antigen.
B) NK cells kill their target cells by phagocytosis and intracellular digestion.
C) NK cells are a subset of polymorphonuclear cells.
D) NK-cell killing is extracellular.
E) NK cells are particularly effective against certain bacteria. - Correct Answers -D
A large glycoprotein has been enzymatically digested in the laboratory to yield a mixture
of glycopeptides ranging in size from 4 to 6 amino acids in length. Which of the following
would be expected if the peptide mixture were administered to an exerimental animal
together with an adjuvant such as complete Freund's adjuvant?
A) peptide-specific antibodies would be generated using the peptide mixture alone
B) carbohydrate-specific antibodies would be generated only if an adjuvant were
administered with the peptide mixture
C) peptide-specific antibodies would be generated only if they were injected with a
separate uncoupled protein carrier
D) peptide-specific and carbohydrate-specific antibody and T-cell responses would be
generated using the peptide mixture alone
E) there would be neither a humoral nor cell-mediated immune response to the peptides
in the mixture - Correct Answers -E
The protection against smallpox virus infection afforded by prior infection with cowpox
virus represents
A) antigenic specificity
B) antigenic cross-reactivity
C) enhanced viral uptake by macrophages
D) innate immunity
E) passive protection - Correct Answers -B
EXAM QUESTIONS AND ANSWERS
Which of the following generally does not apply to bone marrow (a primary lymphoid
organ) and secondary lymphoid organs?
A) cellular proliferation
B) differentiation of lymphocytes
C) cellular interaction
D) antigen-dependent response
E) None of the above. - Correct Answers -D
Which of the following apply uniquely to secondary lymphoid organs?
A) presence of precursor B and T cells
B) circulation of lymphocytes
C) terminal differentiation
D) cellular proliferation
E) All of the above. - Correct Answers -C
Which of the following does not apply to "innate" immune mechanisms?
A) absence of specificity
B) activation by a stimulus
C) involvement of multiple cell types
D) a memory component - Correct Answers -D
Which of the following is the major function of the lymphoid system?
A) innate immunity
B) inflammation
C) phagocytosis
D) acquired immunity
E) None of the above. - Correct Answers -D
Removal of the bursa of Fabricius from a chicken results in
A) a markedly decreased number of circulating T lymphocytes.
B) anemia.
, C) delayed rejection of skin graft.
D) low serum levels of antibodies in serum.
E) all of the above.
F) none of the above. - Correct Answers -D
The germinal centers found in the cortical region of lymph nodes and the peripheral
region of splenic periarteriolar lymphatic tissue
A) support the development of immature B and T cells.
B) function in the removal of damaged erythrocytes from the circulation.
C) act as the major source of stem cells and thus help to maintain hematopoiesis.
D) provide an infrastructure that on antigenic stimulation contains large populations of B
lymphocytes and plasma cells.
E) are the sites of NK-cell differentiation. - Correct Answers -D
Which of the following is correct?
A) NK cells proliferate in response to antigen.
B) NK cells kill their target cells by phagocytosis and intracellular digestion.
C) NK cells are a subset of polymorphonuclear cells.
D) NK-cell killing is extracellular.
E) NK cells are particularly effective against certain bacteria. - Correct Answers -D
A large glycoprotein has been enzymatically digested in the laboratory to yield a mixture
of glycopeptides ranging in size from 4 to 6 amino acids in length. Which of the following
would be expected if the peptide mixture were administered to an exerimental animal
together with an adjuvant such as complete Freund's adjuvant?
A) peptide-specific antibodies would be generated using the peptide mixture alone
B) carbohydrate-specific antibodies would be generated only if an adjuvant were
administered with the peptide mixture
C) peptide-specific antibodies would be generated only if they were injected with a
separate uncoupled protein carrier
D) peptide-specific and carbohydrate-specific antibody and T-cell responses would be
generated using the peptide mixture alone
E) there would be neither a humoral nor cell-mediated immune response to the peptides
in the mixture - Correct Answers -E
The protection against smallpox virus infection afforded by prior infection with cowpox
virus represents
A) antigenic specificity
B) antigenic cross-reactivity
C) enhanced viral uptake by macrophages
D) innate immunity
E) passive protection - Correct Answers -B
