Immunology Exam 4 UAMS Questions and
Answers (100% Correct Answers) Already
Graded A+
fetal thymus and bone marrow transplantation and
administration of thymic hormones [ Ans: ] treatment for
DiGeorge anomaly
ABY reacts w/ soluble AGN; complexes precipitate in
tissue [ Ans: ] Type III
Which immunodeficiency are usually inherited
dysfunctions of the immune system? [ Ans: ] Primary
Immunodeficiency diseases
secondary immunodeficiency is due to [ Ans: ] acquired
Cellulary immunity is mediated [ Ans: ] T Cells
Humoral immunity is mediated by: [ Ans: ] B cells
Primary is deficinvies are [ Ans: ] inherited
Defect in one system may cause ______ of
othercomponents (Regulation disrupted) [ Ans: ]
hyperactivity
1. Relatively rare (except IgA deficiency)
2. Inherited defects of the immune system
,3. Most patients present with recurrent infections [ Ans: ]
Primary immunodeficiency syndromes
Transient hypogammaglobulinemia of infancy
X-Linked Bruton's agammaglobulinemia
IgA deficiency
Common variable immunodeficiency (CVI) [ Ans: ] Primary
Deficiencies of the B-cell
1. Prolonged low Ig levels
2. Children have problems with infections
3. Delay in Ig levels has been attributed to poor T cell help
[ Ans: ] Transient hypogammaglobulinemia of infancy
Development of B cell blocked at pro-B cell stage to pre-B
cell stage
Lymphoid tissue (tonsils & adenoids) small or absent
T cells normal [ Ans: ] X-Linked Bruton's
agammaglobulinemia
What enzyme is deficient in X-Linked
agammaglobulinemia [ Ans: ] Burton tyrosine kinase
What gender is prone to inheritng X-Linked
agammaglobulinemia [ Ans: ] males
, Most common congenital immunodeficiency;1/500
caucasians [ Ans: ] IgA deficiency
What is important know about IgA deficiency [ Ans: ]
Important cause of anaphylaxis following blood
transfusions
Is IgA curable? Why? [ Ans: ] No, replacement therapy is
not useful because of the half-life of IgA is short.
Normal number of Mature B cells but cannot differentiate
into Ig producing cells [ Ans: ] Common variable
immunodeficiency (CVI)
Malabsorption & diarrhea
Malignancies
Autoimmune disorders
are symptoms of what disease [ Ans: ] Common variable
immunodeficiency (CVI)
Diagnosis: Low serum IgG in patient with
recurrentbacterial infections [ Ans: ] Common variable
immunodeficiency (CVI)
Intramuscular or IV Ig preparations; antibiotics as needed
[ Ans: ] treatment for Common variable immunodeficiency
(CVI)
Donor cells attack recipient's tissues
Answers (100% Correct Answers) Already
Graded A+
fetal thymus and bone marrow transplantation and
administration of thymic hormones [ Ans: ] treatment for
DiGeorge anomaly
ABY reacts w/ soluble AGN; complexes precipitate in
tissue [ Ans: ] Type III
Which immunodeficiency are usually inherited
dysfunctions of the immune system? [ Ans: ] Primary
Immunodeficiency diseases
secondary immunodeficiency is due to [ Ans: ] acquired
Cellulary immunity is mediated [ Ans: ] T Cells
Humoral immunity is mediated by: [ Ans: ] B cells
Primary is deficinvies are [ Ans: ] inherited
Defect in one system may cause ______ of
othercomponents (Regulation disrupted) [ Ans: ]
hyperactivity
1. Relatively rare (except IgA deficiency)
2. Inherited defects of the immune system
,3. Most patients present with recurrent infections [ Ans: ]
Primary immunodeficiency syndromes
Transient hypogammaglobulinemia of infancy
X-Linked Bruton's agammaglobulinemia
IgA deficiency
Common variable immunodeficiency (CVI) [ Ans: ] Primary
Deficiencies of the B-cell
1. Prolonged low Ig levels
2. Children have problems with infections
3. Delay in Ig levels has been attributed to poor T cell help
[ Ans: ] Transient hypogammaglobulinemia of infancy
Development of B cell blocked at pro-B cell stage to pre-B
cell stage
Lymphoid tissue (tonsils & adenoids) small or absent
T cells normal [ Ans: ] X-Linked Bruton's
agammaglobulinemia
What enzyme is deficient in X-Linked
agammaglobulinemia [ Ans: ] Burton tyrosine kinase
What gender is prone to inheritng X-Linked
agammaglobulinemia [ Ans: ] males
, Most common congenital immunodeficiency;1/500
caucasians [ Ans: ] IgA deficiency
What is important know about IgA deficiency [ Ans: ]
Important cause of anaphylaxis following blood
transfusions
Is IgA curable? Why? [ Ans: ] No, replacement therapy is
not useful because of the half-life of IgA is short.
Normal number of Mature B cells but cannot differentiate
into Ig producing cells [ Ans: ] Common variable
immunodeficiency (CVI)
Malabsorption & diarrhea
Malignancies
Autoimmune disorders
are symptoms of what disease [ Ans: ] Common variable
immunodeficiency (CVI)
Diagnosis: Low serum IgG in patient with
recurrentbacterial infections [ Ans: ] Common variable
immunodeficiency (CVI)
Intramuscular or IV Ig preparations; antibiotics as needed
[ Ans: ] treatment for Common variable immunodeficiency
(CVI)
Donor cells attack recipient's tissues
