NBME 25 Question and answers already needs to be
passed 2025/2026 reas- sayed
1. A 75-year-old man has decreased exercise at a dilution
tolerance and occasional syncopal episodes The results
related to exertion. Left-heart catheterization are pending
discloses this pressure trac- ing (Ao -aorta: LV - Which of th
left ventricle; LA - left atrium). The most following is
frequently encountered mechanism the most
underlying this disorder is which of the likely cause
following? of his
A ) Amyloid deposition condition?
B) Calcification A) Loss-of-
C) Cystic medial necrosis function
D) Pericardial effusion mutation
E } Septal hypertrophy in the
calcium-
2. New reagents are being designed to treat sensing
graft-ver- sus-host disease in HLA-unrelated receptor
bone marrow trans- plant recipients. Reagents
should be designed that selectively deplete
which of the following donor cells?
A ) B lymphocytes
B) Dendritic cells
C) Macrophages
D) Neutrophils
E)T lymphocytes
3. A 9-year-old boy has had alopecia and
hypocalcemia since birth. His serum 1;25-
dihydroxycholecalciferol concentration is within
the reference range: serum 24;25-
dihydroxycholecalciferol is undetectable.Serum
parathyroid hormone concentration is above
the up- per limit of the laboratory assay and
1/
11
,B) Calcification
E) T lymphocytes
D ) Mutations inactivating the vitamin D receptor
2/
11
passed 2025/2026 reas- sayed
1. A 75-year-old man has decreased exercise at a dilution
tolerance and occasional syncopal episodes The results
related to exertion. Left-heart catheterization are pending
discloses this pressure trac- ing (Ao -aorta: LV - Which of th
left ventricle; LA - left atrium). The most following is
frequently encountered mechanism the most
underlying this disorder is which of the likely cause
following? of his
A ) Amyloid deposition condition?
B) Calcification A) Loss-of-
C) Cystic medial necrosis function
D) Pericardial effusion mutation
E } Septal hypertrophy in the
calcium-
2. New reagents are being designed to treat sensing
graft-ver- sus-host disease in HLA-unrelated receptor
bone marrow trans- plant recipients. Reagents
should be designed that selectively deplete
which of the following donor cells?
A ) B lymphocytes
B) Dendritic cells
C) Macrophages
D) Neutrophils
E)T lymphocytes
3. A 9-year-old boy has had alopecia and
hypocalcemia since birth. His serum 1;25-
dihydroxycholecalciferol concentration is within
the reference range: serum 24;25-
dihydroxycholecalciferol is undetectable.Serum
parathyroid hormone concentration is above
the up- per limit of the laboratory assay and
1/
11
,B) Calcification
E) T lymphocytes
D ) Mutations inactivating the vitamin D receptor
2/
11