Page 1 of 61
NR 565-advanced pharmacology midterm
Chamberlain NEWEST WITH COMPLETE
QUESTIONS AND CORRECT VERIFIED ANSWERS
LATEST UPDATE JUST RELEASED THIS YEAR
Question: Physiological changes during pregnancy that impact pharmacodynamics and
pharmacokinetic properties of drugs? - ANSWER✔✔increase glomerular filtration rate leads to
increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Question: Examples of medications that can be teratogenic - ANSWER✔✔Antiepileptic drugs,
antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses, some
anticoagulants, and hormonal medications such as diethylstilbestrol (DES).
Question: How is absorption of intramuscular medications different in neonates? -
ANSWER✔✔slow and erratic due to low blood flow in muscles first few days of life
1
SUCCESS!
,Page 2 of 61
Question: Why is absorption of medication in the stomach increased in infancy? -
ANSWER✔✔delayed gastric emptying
Question: Some medications that should be avoided in the pediatric patient? -
ANSWER✔✔glucocorticoids, discoloration of developing teeth with tetracyclines, and
kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
Q;During what trimester is a pregnant woman most at risk for adverse drug reactions with
potential long term consequences? - ANSWER✔✔1st trimester (fetus most at risk d/t rapid
growth)
Question: What is BEERS criteria? - ANSWER✔✔Recommendations of medications
inappropriate for elderly (65 and older), prescriber ultimately decides
2
SUCCESS!
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Question: What is the CYP450 (cytochrome P450) - ANSWER✔✔liver enzyme system where
medications are metabolized, can either be inducers or inhibitors and create drug-drug
interactions
Question: CYP450 inducers - ANSWER✔✔Speed up metabolism of drugs (drug is cleared
faster), drug has lesser effect (decrease blood levels of drug), elevate CYP450 enzymes
Question: CYP450 inducers pneumonic - ANSWER✔✔"Bullshit Crap GPS INDUCES rage"
Question: CYP450 inducer drug names - ANSWER✔✔Barbituates, St John wort,
Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas
Question: CYP450 inhibitors - ANSWER✔✔inhibit metabolism, increase blood levels of
medications
Question: CYP450 pneumonic - ANSWER✔✔"VISA credit card debt INHIBITS spending on
designers like CK to look GQ"
3
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, Page 4 of 61
Question: CYP450 inhibitors drug names - ANSWER✔✔Valproate, isoniazid, sulfonamides,
amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine
Question: what should be included in medication administration patient education? -
ANSWER✔✔dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
Question: What are some things that put the elderly patient at higher risk for adverse drug
reactions? - ANSWER✔✔reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
4
SUCCESS!
NR 565-advanced pharmacology midterm
Chamberlain NEWEST WITH COMPLETE
QUESTIONS AND CORRECT VERIFIED ANSWERS
LATEST UPDATE JUST RELEASED THIS YEAR
Question: Physiological changes during pregnancy that impact pharmacodynamics and
pharmacokinetic properties of drugs? - ANSWER✔✔increase glomerular filtration rate leads to
increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Question: Examples of medications that can be teratogenic - ANSWER✔✔Antiepileptic drugs,
antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses, some
anticoagulants, and hormonal medications such as diethylstilbestrol (DES).
Question: How is absorption of intramuscular medications different in neonates? -
ANSWER✔✔slow and erratic due to low blood flow in muscles first few days of life
1
SUCCESS!
,Page 2 of 61
Question: Why is absorption of medication in the stomach increased in infancy? -
ANSWER✔✔delayed gastric emptying
Question: Some medications that should be avoided in the pediatric patient? -
ANSWER✔✔glucocorticoids, discoloration of developing teeth with tetracyclines, and
kernicterus with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
Q;During what trimester is a pregnant woman most at risk for adverse drug reactions with
potential long term consequences? - ANSWER✔✔1st trimester (fetus most at risk d/t rapid
growth)
Question: What is BEERS criteria? - ANSWER✔✔Recommendations of medications
inappropriate for elderly (65 and older), prescriber ultimately decides
2
SUCCESS!
,Page 3 of 61
Question: What is the CYP450 (cytochrome P450) - ANSWER✔✔liver enzyme system where
medications are metabolized, can either be inducers or inhibitors and create drug-drug
interactions
Question: CYP450 inducers - ANSWER✔✔Speed up metabolism of drugs (drug is cleared
faster), drug has lesser effect (decrease blood levels of drug), elevate CYP450 enzymes
Question: CYP450 inducers pneumonic - ANSWER✔✔"Bullshit Crap GPS INDUCES rage"
Question: CYP450 inducer drug names - ANSWER✔✔Barbituates, St John wort,
Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas
Question: CYP450 inhibitors - ANSWER✔✔inhibit metabolism, increase blood levels of
medications
Question: CYP450 pneumonic - ANSWER✔✔"VISA credit card debt INHIBITS spending on
designers like CK to look GQ"
3
SUCCESS!
, Page 4 of 61
Question: CYP450 inhibitors drug names - ANSWER✔✔Valproate, isoniazid, sulfonamides,
amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine
Question: what should be included in medication administration patient education? -
ANSWER✔✔dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
Question: What are some things that put the elderly patient at higher risk for adverse drug
reactions? - ANSWER✔✔reduced renal function
polypharmacy (the use of five or more medications daily)
greater severity of illness
4
SUCCESS!
