CONTROLLED SUBSTANCES UNIT 2-
NU 578 EXAM 2026 QUESTIONS AND
ANSWERS| ACE YOUR GRADES.
pentazocine pharmacokinetics - correct answer -• acts as an
agonist at kappa
receptors and as an
antagonist at mu receptors.
By activating kappa receptors,
the drug produces analgesia,
sedation, and respiratory
depression. However, unlike
the respiratory depression
caused by morphine,
respiratory depression caused
by pentazocine is limited.
**If administered to a patient
who is physically dependent
on a pure opioid agonist,
pentazocine can precipitate
withdrawal-PO
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Pentazocine a/e - correct answer -Increases cardiac work;
otherwise
similar to pure opioid agonists
Pentazocine C/I - correct answer -MI, Those who are physically
dependent to a pure opioid
agonist
Reverse with Narcan
Nalbuphine - correct answer -Partial opioid agonist
& Agonist-Antagonist
Opioids
Not listed as a
controlled substance
Nubain - correct answer -Has analgesic action =to
morphine at low dosages
As the dose increases the a
ceiling to analgesia is
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reached; therefore, max
relief lower than that of
morphine
Ceiling to resp depression
IV, IM, subQ
*avoid in L&D
Butorphanol
(STADOL) - correct answer -Partial opioid agonist
& Agonist-Antagonist
Opioids SCH IV
Stadol s/e - correct answer -Increase cardiac work
stadol C/I - correct answer -AVOID MI
Buprenorphin
e (Buprenex) - correct answer -Partial opioid agonist
& Agonist-Antagonist