PREP 2026 TEST PAPER
◉ For healthy individuals at rest, which of the following statements
about exhalation is true? Answer: Exhalation will be passive, due to
inspiratory stored potential energy.
◉ Why is the total mechanical work of breathing difficult to assess
during spontaneous breathing? Answer: Respiratory muscle activity
contributes to inflation resistance.
◉ On inspecting a volume-pressure curve of the lungs and thorax, an
increase in the mechanical work of breathing above normal would
always be indicated by which of the following? Answer: increase in
the area of the volume-pressure curve
◉ In health, about what proportion of the total work of breathing is
attributable to frictional resistance to gas and tissue movement?
Answer: 1/3
◉ In individuals with disorders characterized by an increased
frictional work of breathing, such as emphysema, which of the
following breathing patterns results in the minimum work? Answer:
slow and deep breathing
,◉ All of the following will cause an increase in the pressure energy
required for inspiration EXCEPT which one? Answer: increased
compliance
◉ increased compliance Answer: ...
◉ In a normal individual, what is the oxygen cost of breathing as a
percentage of the body's total oxygen consumption? Answer: 5%
◉ In a normal individual lying on the right side (right side down),
which of the following conditions would be true? Answer: The right
lung would receive the most ventilation.
◉ Which of the following statements apply to a lung unit with higher
resistance than normal? Answer: There will be less volume change
for a given pressure change.
◉ Which of the following formulas are used to compute the time
constant of a lung unit? Answer: resistance ´ compliance
◉ Which of the following lung units would empty and fill most
slowly? Answer: a unit with high resistance and high compliance
, ◉ For a given transpulmonary pressure gradient and inflation time,
which of the following lung units would exhibit the greatest change
in volume? Answer: a unit with normal resistance and normal
compliance
◉ If a patient has a VT of 370 ml and a respiratory rate of 20 breaths
per minute, what is the minute ventilation? Answer: 7.40 L/min
◉ A normal 150-lb man is breathing at a rate of 17 with a tidal
volume of 450 ml. By estimation, what is his approximate alveolar
ventilation? Answer: 5.10 L/min
◉ Blockage of the pulmonary arterial circulation to a portion of the
lung would cause which of the following? Answer: increase in
alveolar dead space
◉ Which is the correct formula to calculate the alveolar minute
ventilation of a spontaneously breathing subject? Answer: f ´ (VT -
VDSphys)
◉ In clinical practice measuring the physiologic dead space
ventilation is achieved by using which formula? Answer: modified
Bohr equation