08/12/2025 1
, Objectives
At the end of the lesson, the student should be able to
Define anemia
Differentiate the different types of anemia
Describe the clinical presentations of anemia
Describe the pharmacotherapeutics basis of managing
anemia
Describe the pharmacokinetic and pharmacodynamic effect
of antianemic drugs
08/12/2025 2
, Introduction to Hematopoietic
• Hematopoietic machinery resides primarily in the bone
marrow in adults
• The process requires a constant supply of three essential
nutrients—iron, vitamin B12, and folic acid
– Also the presence of hematopoietic growth factor proteins
regulate the proliferation and differentiation of hematopoietic cells.
• Inadequate supplies of the essential nutrients and the growth
factors result in deficiency of functional blood cells.
08/12/2025 3
, Anemia
• Anemia is a group of diseases characterized by a decrease
in either Hb or RBCs
Resulting in reduced oxygen carrying capacity of the
blood.
• Anemias can result from :
Inadequate RBC production
Increased RBC destruction, or
Blood loss
08/12/2025 4
, Objectives
At the end of the lesson, the student should be able to
Define anemia
Differentiate the different types of anemia
Describe the clinical presentations of anemia
Describe the pharmacotherapeutics basis of managing
anemia
Describe the pharmacokinetic and pharmacodynamic effect
of antianemic drugs
08/12/2025 2
, Introduction to Hematopoietic
• Hematopoietic machinery resides primarily in the bone
marrow in adults
• The process requires a constant supply of three essential
nutrients—iron, vitamin B12, and folic acid
– Also the presence of hematopoietic growth factor proteins
regulate the proliferation and differentiation of hematopoietic cells.
• Inadequate supplies of the essential nutrients and the growth
factors result in deficiency of functional blood cells.
08/12/2025 3
, Anemia
• Anemia is a group of diseases characterized by a decrease
in either Hb or RBCs
Resulting in reduced oxygen carrying capacity of the
blood.
• Anemias can result from :
Inadequate RBC production
Increased RBC destruction, or
Blood loss
08/12/2025 4
