NR 566 FINAL EXAM QUESTIONS AND
ANSWERS. VERIFIED 2025/2026.
Mechanism of action of estrogen and progestin - ANS Diffuses into cells to bind to their
receptors in the cell nucleus. A hormone-receptor complex is formed, which then binds to the
target gene to alter the rate of gene transcription
Estrogen and progestin baseline - ANS HR
BP
Weight
Pregnancy test
Screen for breast cancer
Screen for cardiovascular disease
(estrogen-only) - TSH, triglycerides
Estrogen/progestin contraindications - ANS Abnormal vaginal bleeding
Estrogen-dependent cancers
Breast cancer
Hx thrombus (DVT, PE, MI, CVA) - estrogen only
Abnormal liver function
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,Estrogen adverse effects - ANS - Nausea
- Breast tenderness
- Bloating/Weight gain
- Increased BP
- Thrombosis
Why should estrogen be taken with progestin in menopausal women? - ANS If they take
estrogen alone, there is an increased risk of endometrial cancer
Role of progesterone in menstrual cycle - ANS Secreted in 2nd half of menstrual cycle. If
there is no pregnancy, the levels will decrease
Role of progesterone in pregnancy - ANS Helps maintain pregnancy by preventing uterine
contraction
Decreases GI muscle contraction (causes constipation)
Promotes breast milk production
Increases pH and suppresses pCO2
Suppresses maternal immune system (prevents attack on fetus)
Therapeutic use of progestin - ANS Counteracts endometrial hyperplasia caused by estrogen
alone
Manages dysfunctional uterine bleeding, amenorrhea and endometriosis
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,Supports in vitro and pregnancy in those with corpus luteum deficiency
Progestin adverse effects - ANS breakthrough bleeding, spotting and amenorrhea
patients should report abnormal or prolonged bleeding
What is menopause? - ANS Loss of estrogen that occurs around age 50
Menstrual cycle becomes irregular and then ovulation eventually stops
What are the symptoms of menopause? - ANS Hot flashes/night sweats
Atrophy of urethra (causes frequency and urgency)
Atrophy of vagina (causes dryness and pain w/ intercourse)
Decreased libido/arousal
Memory loss and anxiety
Osteoporosis
Altered lipid metabolism (increases LDL, decreases HDL)
What is doxazosin used for? - ANS nonselective alpha 1 blocker
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, treatment for benign prostatic hyperplasia (BPH)
Side effects of doxazosin - ANS orthostatic hypotension
Beers criteria - doxazosin and terazosin - ANS can cause hypotension, fainting and dizziness
(nonselective alpha blockers)
better to give older adults tamsulosin or dutasteride
When should someone take Viagra before intercourse? - ANS 1 hour before
Nausea is common when first starting____ - ANS estrogen therapies (improves over time)
What type of drug is dutasteride? - ANS 5-alpha reductase inhibitor
What is dutasteride used for? - ANS BPH, especially for those with larger prostates
Dutasteride patient teaching - ANS decreases libido and ejaculate
causes decrease is PSA
teratogenic (don't let pregnant woman handle it and don't donate blood that could be given to
pregnant woman)
capsule must be swallowed whole
Dutasteride delayed onset of therapeutic effect - ANS has long half-life - takes 5 weeks after
stopping the drug to leave the system; takes time to work
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
ANSWERS. VERIFIED 2025/2026.
Mechanism of action of estrogen and progestin - ANS Diffuses into cells to bind to their
receptors in the cell nucleus. A hormone-receptor complex is formed, which then binds to the
target gene to alter the rate of gene transcription
Estrogen and progestin baseline - ANS HR
BP
Weight
Pregnancy test
Screen for breast cancer
Screen for cardiovascular disease
(estrogen-only) - TSH, triglycerides
Estrogen/progestin contraindications - ANS Abnormal vaginal bleeding
Estrogen-dependent cancers
Breast cancer
Hx thrombus (DVT, PE, MI, CVA) - estrogen only
Abnormal liver function
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,Estrogen adverse effects - ANS - Nausea
- Breast tenderness
- Bloating/Weight gain
- Increased BP
- Thrombosis
Why should estrogen be taken with progestin in menopausal women? - ANS If they take
estrogen alone, there is an increased risk of endometrial cancer
Role of progesterone in menstrual cycle - ANS Secreted in 2nd half of menstrual cycle. If
there is no pregnancy, the levels will decrease
Role of progesterone in pregnancy - ANS Helps maintain pregnancy by preventing uterine
contraction
Decreases GI muscle contraction (causes constipation)
Promotes breast milk production
Increases pH and suppresses pCO2
Suppresses maternal immune system (prevents attack on fetus)
Therapeutic use of progestin - ANS Counteracts endometrial hyperplasia caused by estrogen
alone
Manages dysfunctional uterine bleeding, amenorrhea and endometriosis
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,Supports in vitro and pregnancy in those with corpus luteum deficiency
Progestin adverse effects - ANS breakthrough bleeding, spotting and amenorrhea
patients should report abnormal or prolonged bleeding
What is menopause? - ANS Loss of estrogen that occurs around age 50
Menstrual cycle becomes irregular and then ovulation eventually stops
What are the symptoms of menopause? - ANS Hot flashes/night sweats
Atrophy of urethra (causes frequency and urgency)
Atrophy of vagina (causes dryness and pain w/ intercourse)
Decreased libido/arousal
Memory loss and anxiety
Osteoporosis
Altered lipid metabolism (increases LDL, decreases HDL)
What is doxazosin used for? - ANS nonselective alpha 1 blocker
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, treatment for benign prostatic hyperplasia (BPH)
Side effects of doxazosin - ANS orthostatic hypotension
Beers criteria - doxazosin and terazosin - ANS can cause hypotension, fainting and dizziness
(nonselective alpha blockers)
better to give older adults tamsulosin or dutasteride
When should someone take Viagra before intercourse? - ANS 1 hour before
Nausea is common when first starting____ - ANS estrogen therapies (improves over time)
What type of drug is dutasteride? - ANS 5-alpha reductase inhibitor
What is dutasteride used for? - ANS BPH, especially for those with larger prostates
Dutasteride patient teaching - ANS decreases libido and ejaculate
causes decrease is PSA
teratogenic (don't let pregnant woman handle it and don't donate blood that could be given to
pregnant woman)
capsule must be swallowed whole
Dutasteride delayed onset of therapeutic effect - ANS has long half-life - takes 5 weeks after
stopping the drug to leave the system; takes time to work
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
