Oxford Cambridge and RSA
Monday 12 May 2025 – Morning
AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Time allowed: 1 hour 30 minutes
You can use:
* 1 3 2 7 1 0 4 5 8 4 *
• a scientific or graphical calculator
• a ruler (cm/mm)
* H 0 2 2 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] OCR is an exempt Charity
DC (CE/SG) 329633/4 Turn over
for more: tyrionpapers.com
, 2
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the statements about peak expiratory flow rate (PEFR) is correct?
A It increases as the age of a person increases.
B It is calculated by multiplying tidal volume by breathing rate.
C It is the maximum rate at which air can be forced out through the mouth.
D It is the volume of air breathed out in the first second of forced exhalation.
Your answer
[1]
2 Which option about why multicellular plants need transport systems is not correct?
A Assimilates must be transported from source to sink
B Diffusion distances are too long
C Multicellular plants have large surface area to volume ratios
D Water and mineral ions must be transported from roots to leaves
Your answer
[1]
© OCR 2025
for more: tyrionpapers.com
, 3
3 The transmission electron micrograph shows the ultrastructure of a mammalian cell.
P
Which option describes the function of the structure labelled P?
A It produces ATP.
B It stores glycogen.
C It synthesises proteins.
D It synthesises ribosomes.
Your answer
[1]
© OCR 2025 Turn over
for more: tyrionpapers.com
, 4
4 A student observed a blood sample using a light microscope with a calibrated eyepiece graticule.
They measured the diameter of a lymphocyte and calculated its actual diameter as 12 μm.
One unit of the calibrated eyepiece graticule = 2.4 μm.
What is the diameter of the lymphocyte measured by the student in eyepiece graticule units?
A 0.2
B 5.0
C 9.6
D 28.8
Your answer
[1]
5 The graph shows the rate of an enzyme-controlled reaction with and without the addition of a
fixed quantity of substance Z.
Without substance Z
Rate of
reaction With substance Z
Substrate concentration
What is the molecule in substance Z?
A Cofactor
B Competitive inhibitor
C Non-competitive inhibitor
D Prosthetic group
Your answer
[1]
© OCR 2025
for more: tyrionpapers.com
Monday 12 May 2025 – Morning
AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Time allowed: 1 hour 30 minutes
You can use:
* 1 3 2 7 1 0 4 5 8 4 *
• a scientific or graphical calculator
• a ruler (cm/mm)
* H 0 2 2 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] OCR is an exempt Charity
DC (CE/SG) 329633/4 Turn over
for more: tyrionpapers.com
, 2
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the statements about peak expiratory flow rate (PEFR) is correct?
A It increases as the age of a person increases.
B It is calculated by multiplying tidal volume by breathing rate.
C It is the maximum rate at which air can be forced out through the mouth.
D It is the volume of air breathed out in the first second of forced exhalation.
Your answer
[1]
2 Which option about why multicellular plants need transport systems is not correct?
A Assimilates must be transported from source to sink
B Diffusion distances are too long
C Multicellular plants have large surface area to volume ratios
D Water and mineral ions must be transported from roots to leaves
Your answer
[1]
© OCR 2025
for more: tyrionpapers.com
, 3
3 The transmission electron micrograph shows the ultrastructure of a mammalian cell.
P
Which option describes the function of the structure labelled P?
A It produces ATP.
B It stores glycogen.
C It synthesises proteins.
D It synthesises ribosomes.
Your answer
[1]
© OCR 2025 Turn over
for more: tyrionpapers.com
, 4
4 A student observed a blood sample using a light microscope with a calibrated eyepiece graticule.
They measured the diameter of a lymphocyte and calculated its actual diameter as 12 μm.
One unit of the calibrated eyepiece graticule = 2.4 μm.
What is the diameter of the lymphocyte measured by the student in eyepiece graticule units?
A 0.2
B 5.0
C 9.6
D 28.8
Your answer
[1]
5 The graph shows the rate of an enzyme-controlled reaction with and without the addition of a
fixed quantity of substance Z.
Without substance Z
Rate of
reaction With substance Z
Substrate concentration
What is the molecule in substance Z?
A Cofactor
B Competitive inhibitor
C Non-competitive inhibitor
D Prosthetic group
Your answer
[1]
© OCR 2025
for more: tyrionpapers.com
