Chamberlain College of Nursing
Final Exam Study Guide
Module 5: Treatment for Mood Disorders
Module 6: Treatments for Substance Use Disorders
Module 7: Treatments for ADHD & Sleep Disorders
Module 8: Treatments for Alzheimer’s disease and other
Dementias
Course: NR546/NR 546 Advanced
Pharmacology: Psychopharmacology
, Final Exam
Module 5: Treatment for Mood Disorders
Major Depressive Disorder (MDD):
• Review the monoamine hypothesis and its implications for prescribing, focusing on how this
theory informs the selection of antidepressants based on neurotransmitter targets and symptom
profiles
• SSRIs:
o Identify necessary screening prior to prescribing.
o Study age-related risks and which age group requires extra caution.
o Understand which SSRI has the least CYP interactions, best tolerance, and longest half-
life.
o Explore SSRIs associated with discontinuation syndrome, activation, or panic
exacerbation.
• Lithium Interactions:
o Know substances and medications that can affect lithium levels (cause increase or
decrease in lithium level).
• Serotonin Syndrome:
o Know symptoms and causes and what distinguishes serotonin syndrome from other
adverse effects.
• Pharmacological Adjuncts:
o Review medications used alongside SSRIs.
• Medication Comparisons:
o Differentiate between medications that exacerbate anxiety and those pharmacologically
similar to SSRIs and buspirone.
Monoamine Oxidase Inhibitors (MAOIs):
• Understand half-life, interactions, benefits, and adverse effects.
Bipolar Disorder:
• Review the half-life, interactions, and adverse effects of mood stabilizers. Know how half-life
influences dosing frequency and patient adherence to treatment plans.
• Explore side effects unique to this medication class and specific treatments for common adverse
reactions.
General Medication Knowledge:
• What medication should be avoided in clients with an eating disorder? Why?
• Review the mechanism of action (MOA), adverse reactions, indications, starting doses, and
necessary lab tests.
• Which medication has a risk priapism?
• Understand neurotransmitter actions beyond 5HT (such as norepinephrine, dopamine and GABA)
and how these subtypes influence treatment outcomes in anxiety and depression.