BCH 367 CH-6 UPDATED EXAM QUESTIONS
AND CORRECT ANSWERS
Which of the following is true of a holoenzyme but not an apoenzyme?
a) contains a cofactor
b) is catalytically inactive
c) contains a denatured active site
d) contains more than one active site
e) is both catalytically inactive and contains a denatured active site - CORRECT
ANSWERS a
An enzyme cannot alter the laws of thermodynamics and consequently cannot alter the _____
of a chemical reaction. - CORRECT ANSWERS equilibrium
The essence of catalysis is stabilization of the _____. - CORRECT ANSWERS transition state
A reaction must have a very slow uncatalyzed rate in order to have a:
a) fast rate enhancement.
b) fast catalyzed rate.
c) long nonenzymatic half-life.
d) negative Δ G. - CORRECT ANSWERS c
If a reaction has a ΔG that is positive, it is a(n) _____ reaction. - CORRECT
ANSWERS endergonic
, Which class of enzyme adds atoms or functional groups to a double bond?
a) transferases
b) lyases
c) oxidoreductases
d) ligases
e) isomerases - CORRECT ANSWERS b
ΔG‡ is the _____ of a reaction. - CORRECT ANSWERS free energy of activation
If you were to design a transition-state analog that would act as an inhibitor of trypsin, which of
the following may you include in the design?
a) a geometry equivalent to the substrates of trypsin
b) a geometry equivalent to the products of trypsin
c) a charge equivalent to that found in the transition state of the reaction catalyzed
d) a charge equivalent to that found in the substrates of trypsin - CORRECT ANSWERS c
In a system at equilibrium:
a) there is no net change in the concentrations of the products and reactants.
b) ΔG is zero.
c) ΔG‡ is zero.
d) there is no net change in the concentrations of the products and reactants and ΔG is zero.
AND CORRECT ANSWERS
Which of the following is true of a holoenzyme but not an apoenzyme?
a) contains a cofactor
b) is catalytically inactive
c) contains a denatured active site
d) contains more than one active site
e) is both catalytically inactive and contains a denatured active site - CORRECT
ANSWERS a
An enzyme cannot alter the laws of thermodynamics and consequently cannot alter the _____
of a chemical reaction. - CORRECT ANSWERS equilibrium
The essence of catalysis is stabilization of the _____. - CORRECT ANSWERS transition state
A reaction must have a very slow uncatalyzed rate in order to have a:
a) fast rate enhancement.
b) fast catalyzed rate.
c) long nonenzymatic half-life.
d) negative Δ G. - CORRECT ANSWERS c
If a reaction has a ΔG that is positive, it is a(n) _____ reaction. - CORRECT
ANSWERS endergonic
, Which class of enzyme adds atoms or functional groups to a double bond?
a) transferases
b) lyases
c) oxidoreductases
d) ligases
e) isomerases - CORRECT ANSWERS b
ΔG‡ is the _____ of a reaction. - CORRECT ANSWERS free energy of activation
If you were to design a transition-state analog that would act as an inhibitor of trypsin, which of
the following may you include in the design?
a) a geometry equivalent to the substrates of trypsin
b) a geometry equivalent to the products of trypsin
c) a charge equivalent to that found in the transition state of the reaction catalyzed
d) a charge equivalent to that found in the substrates of trypsin - CORRECT ANSWERS c
In a system at equilibrium:
a) there is no net change in the concentrations of the products and reactants.
b) ΔG is zero.
c) ΔG‡ is zero.
d) there is no net change in the concentrations of the products and reactants and ΔG is zero.
