Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
Y Y Y Y Y Y Y Y Y
FULL TESTBANK
Y
RRRRRRINSTANT DOWNLOAD!!
Y
,Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
Y Y Y Y Y Y Y Y Y
ChapterY1.YIntroduction:YTheYNatureYofYDrugsY&YDrugYDevelopmentY&YRegulation
1.
AYnurseYworkingYinYradiologyYadministersYiodineYtoYaYpatientYwhoYisYhavi
ngYaYcomputedYtomographyY(CT)Yscan.YTheYnurseYworkingYonYtheYoncologyY
unitYadministersYchemotherapyYtoYpatientsYwhoYhaveYcancer.YAtYtheYPublicYH
ealthYDepartment,YaYnurseYadministersYaYmeasles-mumps-
rubellaY(MMR)YvaccineYtoYaY14-month-
oldYchildYasYaYroutineYimmunization.YWhichYbranchYofYpharmacologyYbestYde
scribesYtheYactionsYofYallYthreeY nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
PharmacologyYisYtheYstudyYofYtheYbiologicYeffectsYofYchemicals.YNursesYareYi
nvolvedYwithYclinicalYpharmacologyYorYpharmacotherapeutics,YwhichYisYaYbr
anchYofYpharmacologyYthatYdealsYwithYtheYusesYofYdrugsYtoYtreat,Yprevent,Yan
dYdiagnoseYdisease.YTheYradiologyYnurseYisYadministeringYaYdrugYtoYhelpYdia
gnoseYaYdisease.YTheYoncologyYnurseYisYadministeringYaYdrugYtoYhelpYtreatYaY
disease.YPharmacoeconomicsYincludesYanyYcostsYinvolvedYinYdrugYtherapy.
PharmacodynamicsYinvolvesYhowYaYdrugYaffectsYtheYbodyYandYpharmacokinet
icsYisYhowYtheYbodyYactsYonYtheYbody.
2.
AYphysicianYhasYorderedYintramuscularY(IM)YinjectionsYofYmorphine,YaYna
rcotic,YeveryY4YhoursYasYneededYforYpainYinYaYmotorYvehicleYaccidentYvictim.
YTheYnurseYisYawareYthisYdrugYhasYaYhighYabuseYpotential.YUnderYwhatYcateg
oryYwouldYmorphineYbeYclassified?
,A) ScheduleYI
B) ScheduleYII
C) ScheduleYIII
D) ScheduleYIV
Ans: B
Feedback:
NarcoticsYwithYaYhighYabuseYpotentialYareYclassifiedYasYScheduleYIIYdrugsYb
ecauseYofYsevereYdependenceYliability.YScheduleYIYdrugsYhaveYhighYabuseYp
otentialYandYnoYacceptedYmedicalYuse.YScheduleYIIIYdrugsYhaveYaYlesserYabu
seYpotentialYthanYIIYandYanYacceptedYmedicalYuse.YScheduleYIVYdrugsYhaveYl
owYabuseYpotentialYandYlimitedYdependenceYliability.
3.
WhenYinvolvedYinYphaseYIIIYdrugYevaluationYstudies,YwhatYresponsibili
tiesYwouldYtheYnurseYhave?
A) WorkingYwithYanimalsYwhoYareYgivenYexperimentalY drugs
B) ChoosingYappropriateYpatientsYtoYbeYinvolvedYinYtheYdrugY study
C) MonitoringYandYobservingYpatientsYcloselyYforYadverseY effects
D) ConductingYresearchYtoYdetermineYeffectivenessYofYtheY drug
Ans: C
Feedback:
PhaseYIIIYstudiesYinvolveYuseYofYaYdrugYinYaYvastYclinicalYpopulationYinYwhic
hYpatientsYareYaskedYtoYrecordYanyYsymptomsYtheyYexperienceYwhileYtakingYt
heYdrugs.YNursesYmayYbeYresponsibleYforYhelpingYcollectYandYanalyzeYtheYinf
ormationYtoYbeYsharedYwithYtheYFoodYandYDrugYAdministrationY(FDA)YbutYw
ouldYnotYconductYresearchYindependentlyYbecauseYnursesYdoYnotYprescribeYm
edications.YUseYofYanimalsYinYdrugYtestingYisYdoneYinYtheYpreclinicalYtrials.YS
electYpatientsYwhoYareYinvolvedYinYphaseYIIYstudiesYtoYparticipateYinYstudiesY
whereYtheYparticipantsYhaveYtheYdiseaseYtheYdrugYisYintendedYtoYtreat.YTheseY
patientsYareYmonitoredYcloselyYforYdrugYactionYandYadverseYeffects.YPhaseYIY
studiesYinvolveYhealthyYhumanYvolunteersYwhoYareYusuallyYpaidYforYtheirYpa
rticipation.YNursesYmayYobserveYforYadverseYeffectsYandYtoxicity.
, 4.
WhatYconceptYisYconsideredYwhenYgenericYdrugsYareYsubstitutedYforYbr
andYnameYdrugs?
A) Bioavailability
B) CriticalYconcentration
C) Distribution
D) Half-life
Ans: A
Feedback:
BioavailabilityYisYtheYportionYofYaYdoseYofYaYdrugYthatYreachesYtheYsystemicY
circulationYandYisYavailableYtoYactYonYbodyYcells.YBindersYusedYinYaYgenericY
drugYmayYnotYbeYtheYsameYasYthoseYusedYinYtheYbrandYnameYdrug.YTherefor
e,YtheYwayYtheYbodyYbreaksYdownYandYusesYtheYdrugYmayYdiffer,YwhichYma
yYeliminateYaYgenericYdrugYsubstitution.YCriticalYconcentrationYisYtheYamoun
tYofYaYdrugYthatYisYneededYtoYcauseYaYtherapeuticYeffectYandYshouldYnotYdiffe
rYbetweenYgenericYandYbrandYnameYmedications.YDistributionYisYtheYphaseYo
fYpharmacokinetics,YwhichYinvolvesYtheYmovementYofYaYdrugYtoYtheYbodysYt
issuesYandYisYtheYsameYinYgenericYandYbrandYnameYdrugs.YAYdrugsYhalf-
lifeYisYtheYtimeYitYtakesYforYtheYamountYofYdrugYtoYdecreaseYtoYhalfYtheYpeak
Ylevel,YwhichYshouldYnotYchangeYwhenYsubstitutingYaYgenericY medication.
5.
AYnurseYisYassessingYtheYpatientsYhomeYmedicationYuse.YAfterYlisteningYto
YtheYpatientYlistYcurrentYmedications,YtheYnurseYasksYwhatYpriorityYquestion
?
A) DoYyouYtakeYanyYgenericYmedications?
B) AreYanyYofYtheseYmedicationsYorphanY drugs?
C) AreYtheseYmedicationsYsafeYtoYtakeYduringY pregnancy?
D) DoYyouYtakeYanyYover-the-counterYmedications?
Ans: D
Feedback:
Y Y Y Y Y Y Y Y Y
FULL TESTBANK
Y
RRRRRRINSTANT DOWNLOAD!!
Y
,Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
Y Y Y Y Y Y Y Y Y
ChapterY1.YIntroduction:YTheYNatureYofYDrugsY&YDrugYDevelopmentY&YRegulation
1.
AYnurseYworkingYinYradiologyYadministersYiodineYtoYaYpatientYwhoYisYhavi
ngYaYcomputedYtomographyY(CT)Yscan.YTheYnurseYworkingYonYtheYoncologyY
unitYadministersYchemotherapyYtoYpatientsYwhoYhaveYcancer.YAtYtheYPublicYH
ealthYDepartment,YaYnurseYadministersYaYmeasles-mumps-
rubellaY(MMR)YvaccineYtoYaY14-month-
oldYchildYasYaYroutineYimmunization.YWhichYbranchYofYpharmacologyYbestYde
scribesYtheYactionsYofYallYthreeY nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
PharmacologyYisYtheYstudyYofYtheYbiologicYeffectsYofYchemicals.YNursesYareYi
nvolvedYwithYclinicalYpharmacologyYorYpharmacotherapeutics,YwhichYisYaYbr
anchYofYpharmacologyYthatYdealsYwithYtheYusesYofYdrugsYtoYtreat,Yprevent,Yan
dYdiagnoseYdisease.YTheYradiologyYnurseYisYadministeringYaYdrugYtoYhelpYdia
gnoseYaYdisease.YTheYoncologyYnurseYisYadministeringYaYdrugYtoYhelpYtreatYaY
disease.YPharmacoeconomicsYincludesYanyYcostsYinvolvedYinYdrugYtherapy.
PharmacodynamicsYinvolvesYhowYaYdrugYaffectsYtheYbodyYandYpharmacokinet
icsYisYhowYtheYbodyYactsYonYtheYbody.
2.
AYphysicianYhasYorderedYintramuscularY(IM)YinjectionsYofYmorphine,YaYna
rcotic,YeveryY4YhoursYasYneededYforYpainYinYaYmotorYvehicleYaccidentYvictim.
YTheYnurseYisYawareYthisYdrugYhasYaYhighYabuseYpotential.YUnderYwhatYcateg
oryYwouldYmorphineYbeYclassified?
,A) ScheduleYI
B) ScheduleYII
C) ScheduleYIII
D) ScheduleYIV
Ans: B
Feedback:
NarcoticsYwithYaYhighYabuseYpotentialYareYclassifiedYasYScheduleYIIYdrugsYb
ecauseYofYsevereYdependenceYliability.YScheduleYIYdrugsYhaveYhighYabuseYp
otentialYandYnoYacceptedYmedicalYuse.YScheduleYIIIYdrugsYhaveYaYlesserYabu
seYpotentialYthanYIIYandYanYacceptedYmedicalYuse.YScheduleYIVYdrugsYhaveYl
owYabuseYpotentialYandYlimitedYdependenceYliability.
3.
WhenYinvolvedYinYphaseYIIIYdrugYevaluationYstudies,YwhatYresponsibili
tiesYwouldYtheYnurseYhave?
A) WorkingYwithYanimalsYwhoYareYgivenYexperimentalY drugs
B) ChoosingYappropriateYpatientsYtoYbeYinvolvedYinYtheYdrugY study
C) MonitoringYandYobservingYpatientsYcloselyYforYadverseY effects
D) ConductingYresearchYtoYdetermineYeffectivenessYofYtheY drug
Ans: C
Feedback:
PhaseYIIIYstudiesYinvolveYuseYofYaYdrugYinYaYvastYclinicalYpopulationYinYwhic
hYpatientsYareYaskedYtoYrecordYanyYsymptomsYtheyYexperienceYwhileYtakingYt
heYdrugs.YNursesYmayYbeYresponsibleYforYhelpingYcollectYandYanalyzeYtheYinf
ormationYtoYbeYsharedYwithYtheYFoodYandYDrugYAdministrationY(FDA)YbutYw
ouldYnotYconductYresearchYindependentlyYbecauseYnursesYdoYnotYprescribeYm
edications.YUseYofYanimalsYinYdrugYtestingYisYdoneYinYtheYpreclinicalYtrials.YS
electYpatientsYwhoYareYinvolvedYinYphaseYIIYstudiesYtoYparticipateYinYstudiesY
whereYtheYparticipantsYhaveYtheYdiseaseYtheYdrugYisYintendedYtoYtreat.YTheseY
patientsYareYmonitoredYcloselyYforYdrugYactionYandYadverseYeffects.YPhaseYIY
studiesYinvolveYhealthyYhumanYvolunteersYwhoYareYusuallyYpaidYforYtheirYpa
rticipation.YNursesYmayYobserveYforYadverseYeffectsYandYtoxicity.
, 4.
WhatYconceptYisYconsideredYwhenYgenericYdrugsYareYsubstitutedYforYbr
andYnameYdrugs?
A) Bioavailability
B) CriticalYconcentration
C) Distribution
D) Half-life
Ans: A
Feedback:
BioavailabilityYisYtheYportionYofYaYdoseYofYaYdrugYthatYreachesYtheYsystemicY
circulationYandYisYavailableYtoYactYonYbodyYcells.YBindersYusedYinYaYgenericY
drugYmayYnotYbeYtheYsameYasYthoseYusedYinYtheYbrandYnameYdrug.YTherefor
e,YtheYwayYtheYbodyYbreaksYdownYandYusesYtheYdrugYmayYdiffer,YwhichYma
yYeliminateYaYgenericYdrugYsubstitution.YCriticalYconcentrationYisYtheYamoun
tYofYaYdrugYthatYisYneededYtoYcauseYaYtherapeuticYeffectYandYshouldYnotYdiffe
rYbetweenYgenericYandYbrandYnameYmedications.YDistributionYisYtheYphaseYo
fYpharmacokinetics,YwhichYinvolvesYtheYmovementYofYaYdrugYtoYtheYbodysYt
issuesYandYisYtheYsameYinYgenericYandYbrandYnameYdrugs.YAYdrugsYhalf-
lifeYisYtheYtimeYitYtakesYforYtheYamountYofYdrugYtoYdecreaseYtoYhalfYtheYpeak
Ylevel,YwhichYshouldYnotYchangeYwhenYsubstitutingYaYgenericY medication.
5.
AYnurseYisYassessingYtheYpatientsYhomeYmedicationYuse.YAfterYlisteningYto
YtheYpatientYlistYcurrentYmedications,YtheYnurseYasksYwhatYpriorityYquestion
?
A) DoYyouYtakeYanyYgenericYmedications?
B) AreYanyYofYtheseYmedicationsYorphanY drugs?
C) AreYtheseYmedicationsYsafeYtoYtakeYduringY pregnancy?
D) DoYyouYtakeYanyYover-the-counterYmedications?
Ans: D
Feedback:
