CCTN Exam Updated Actual Questions
and CORRECT Answers
Most common diseases requiring pancreas transplant - CORRECT ANSWER Type 1
DM without signs of advanced diabetic nephropathy
Most common diseases requiring liver transplant - CORRECT ANSWER Alcoholism
Cholestatis
Chronic Hepatitis
Genetic Diseases
Metabolic Diseases
Cholestasis - CORRECT ANSWER Bile cannot flow from liver to duodenum
Causes of ESRD - CORRECT ANSWER HTN
DM
glomerulonephritis
PKD
HIV
lupus
Reasons for Intestinal Transplant - CORRECT ANSWER Chron's disease
Small Bowel Stenosis
Necrotizing entercolitis
Trauma
Vascular Accidents
Mesenteric thrombosis, atresia, or stenosis
,Hirschsprung disease - CORRECT ANSWER congenital megacolon with improper
peristalsis resulting in intestinal obstruction, pediatric need for transplant
Chronic intestinal pseudo-obstruction - CORRECT ANSWER A rare obstructive gut
motility disorder of the muscles and nerves in the intestine, pediatric need for transplant
Pediatric indication for intestinal transplant - CORRECT ANSWER Hirschsprung
disease
chronic intestinal pseudo obstruction
volvulus
gastroschisis (abdominal wall herniation)
congenital atresia
necrotizing enterocolitis
trauma
short gut syndrome
Short gut syndrome - CORRECT ANSWER the inability of the small intestine to
adequately absorb nutrition, fluids, and to regulate electrolytes, can be structural or
functional, usually acquired
Indications for Heart Transplant - CORRECT ANSWER CHF with Class 3-4
symptoms, max therapy, reduced exercise capacity, severe O2 dependence
End stage heart disease
Myocarditis
Myxomas
Refractory angina
Restrictive, dilated, or ischemic cardiomyopathy
life-threatening V arrhythmias
Pre Transplant Diagnostic Tests - CORRECT ANSWER Abdominal US
, CXR
EKG
PFT
Panorex
Right heart cath (if indicated)
Pre Transplant Lab Tests - CORRECT ANSWER ABO Rh
Virology Screening
Panel Reactive Antibody
Human Leukocyte Antibody
Toxoplasma Screening
Cancer Screening
Osteoporosis Screening
TB Screening
Virology Screening - CORRECT ANSWER determines recipients suitability for
transplant and post transplant infection risk; HIV, EBV, CMV, Hepatitis, RPR (syphilis), TB,
toxoplasma, herpes
Panel Reactive Antibody (PRA) - CORRECT ANSWER The percent PRA value is a
measure of a patient's level of sensitization to donor antigens. It is the percentage of cells
from a panel of blood donors against which a potential recipient's serum reacts. The PRA
reflects the percentage of the general population that a potential recipient makes antibodies
(is sensitized) against. The higher the PRA, the more sensitized a patient is to the general
donor pool, and thus the more difficult it is to find a suitable donor. A patient may become
sensitized as a result of pregnancy, a blood transfusion, or a previous transplant.
Human Leukocyte Antigen (HLA) - CORRECT ANSWER Molecules found on all
nucleated cells in the body that help the immune system to recognize whether or not a cell is
foreign to the body. Human leukocyte antigens are used to predict likelihood of organ
rejection, cannot test within 72 hours of a blood transfusion, on chromosome 6
and CORRECT Answers
Most common diseases requiring pancreas transplant - CORRECT ANSWER Type 1
DM without signs of advanced diabetic nephropathy
Most common diseases requiring liver transplant - CORRECT ANSWER Alcoholism
Cholestatis
Chronic Hepatitis
Genetic Diseases
Metabolic Diseases
Cholestasis - CORRECT ANSWER Bile cannot flow from liver to duodenum
Causes of ESRD - CORRECT ANSWER HTN
DM
glomerulonephritis
PKD
HIV
lupus
Reasons for Intestinal Transplant - CORRECT ANSWER Chron's disease
Small Bowel Stenosis
Necrotizing entercolitis
Trauma
Vascular Accidents
Mesenteric thrombosis, atresia, or stenosis
,Hirschsprung disease - CORRECT ANSWER congenital megacolon with improper
peristalsis resulting in intestinal obstruction, pediatric need for transplant
Chronic intestinal pseudo-obstruction - CORRECT ANSWER A rare obstructive gut
motility disorder of the muscles and nerves in the intestine, pediatric need for transplant
Pediatric indication for intestinal transplant - CORRECT ANSWER Hirschsprung
disease
chronic intestinal pseudo obstruction
volvulus
gastroschisis (abdominal wall herniation)
congenital atresia
necrotizing enterocolitis
trauma
short gut syndrome
Short gut syndrome - CORRECT ANSWER the inability of the small intestine to
adequately absorb nutrition, fluids, and to regulate electrolytes, can be structural or
functional, usually acquired
Indications for Heart Transplant - CORRECT ANSWER CHF with Class 3-4
symptoms, max therapy, reduced exercise capacity, severe O2 dependence
End stage heart disease
Myocarditis
Myxomas
Refractory angina
Restrictive, dilated, or ischemic cardiomyopathy
life-threatening V arrhythmias
Pre Transplant Diagnostic Tests - CORRECT ANSWER Abdominal US
, CXR
EKG
PFT
Panorex
Right heart cath (if indicated)
Pre Transplant Lab Tests - CORRECT ANSWER ABO Rh
Virology Screening
Panel Reactive Antibody
Human Leukocyte Antibody
Toxoplasma Screening
Cancer Screening
Osteoporosis Screening
TB Screening
Virology Screening - CORRECT ANSWER determines recipients suitability for
transplant and post transplant infection risk; HIV, EBV, CMV, Hepatitis, RPR (syphilis), TB,
toxoplasma, herpes
Panel Reactive Antibody (PRA) - CORRECT ANSWER The percent PRA value is a
measure of a patient's level of sensitization to donor antigens. It is the percentage of cells
from a panel of blood donors against which a potential recipient's serum reacts. The PRA
reflects the percentage of the general population that a potential recipient makes antibodies
(is sensitized) against. The higher the PRA, the more sensitized a patient is to the general
donor pool, and thus the more difficult it is to find a suitable donor. A patient may become
sensitized as a result of pregnancy, a blood transfusion, or a previous transplant.
Human Leukocyte Antigen (HLA) - CORRECT ANSWER Molecules found on all
nucleated cells in the body that help the immune system to recognize whether or not a cell is
foreign to the body. Human leukocyte antigens are used to predict likelihood of organ
rejection, cannot test within 72 hours of a blood transfusion, on chromosome 6
