QUESTIONS AND ANSWERS | WITH COMPLETE
SOLUTION
During therapy with hemtopoietic drugs, the nurse will monitor the patient for
which adverse effects? SATA
a. diarrhea
b. edema
c. nausea and vomiting
d. hypotension
e. headache
f. black tarry stools Answer - a,b,c,e
A patient is to receive filgrastim (Neupogen) 5 mcg/kg/day. The patient weighs
198 lbs. Calculate how many micrograms of medication this patient will receive
each day.
a. 450 mcg
b. 4.5 mcg
c. 45 mcg
d. 4500 mcg Answer - a
What is the general action of immunosuppressants?
a. they inhibit T-lymphocytes
b. they increase natural killer cellular activity
,c. they increase antibody response
d. they re hepatic metabolism of steroids Answer - a
The nurse should teach the client about which expected adverse effect of
filgastrim (Neupogen)?
a. insomnia
b. constipation
c. bone pain
d. hypotension Answer - c
Which client finding would the nurse hold the prescribed dose of filgastrim
(Neupogen) for and notify the health care provider about?
a. blood pressure of 142/88 mm Hg
b. absolute neutrophil count (ANC) 12,000
c. temperature of 99.5 F
d. WBC count of 4.5 Answer - b
A patient is prescribed monoclonal antibody therapy for the treatment of
rheumatoid arthritis. What patient condition should alter the nurse to question
the prescription for this class of drug?
a. Nephrotic syndrome
b. acquired immune deficiency syndrome (AIDS)
c. Chronic obstructive pulmonary disease
d. hypertensive emergency Answer - b
What are the functional cells of the humoral immune system that mature into
immunoglobulins?
a. RBCs
,b. anulocytes
c. B cells
d. T cells Answer - c
What is the mechanism of action of biologic response modifying drugs? SATA
a. interuption of the cell lifecycle at the genetic level to interfere with growth of
the cancer cell
b. direct toxic effect on tumor cells, causing them to rupture
c. enhancement or restoration of the host's immune system defenses against a
tumor
d. regulation of genes expression that occurs during transcription
e. adverse modification of a tumor's biology, making it harder for the tumor
cells to survive and reproduce Answer - b,c,e
When monitoring a patient's response to interferon therapy, the nurse notes
that the major dose-limiting factors for interferon therapy is which condition?
a. nausea and vomiting
b. fatigue
c. diarrhea
d. anxiety Answer - b
A patient asks about his cancer treatment with monoclonal antibodies. The
nurse tell him that which is the major advantage of treating certain cancers
with monoclonal antibodies?
a. they are more effective against metastatic tumors
b. they will help the patient improve more quickly than will other
antineoplastic drugs
c. there are fewer incidences of opportunistic infections with monoclonal
antibodies
, d. monoclonal antibodies target certain tumor cells and bypass normal cells
Answer - d
During a patient's therapy with interleukins, the nurse monitors the patient for
capillary leak syndrome. Which assessment finding, if present, would indicate
this problem?
a. a dry cough
b. bruising on the skin
c. bradycardia
d. a sudden 15 pound weight gain Answer - d
A patient who has received chemotherapy has a steadily decreasing white
blood cell count. The chemotherapy will end on Tuesday afternoon. The
oncologist has mentioned that a colony-stimulating factor will be started soon.
The nurse knows that the appropriate time to start this medication is when?
a.in 2 to 4 days, after the white blood cells have reached their nadir
b. two hours after the chemotherapy ends
c. while the patient is still receiving chemotherapy
d. Wednesday afternoon 24 hours after the chemotherapy ends Answer - d
A patient has an order for the monoclonal antibody. The nurse notes that the
patient does not have a history of cancer. What is another possible reason for
administering this drug?
a. thrombocytopenia
b. rheumatoid arthritis
c. severe anemia
d. osteoporosis Answer - b