LAT Laboratory Animal Technician
Questions and Answers
U.S. |Government |provides |approximately |how |much |in |research/development |funds
|
spent |by |college |and |university?
✓ ~~~2/3
What |information |is |important |on |grant |applications |to |request |funds?
✓ ~~~Detailed |description |of |research |goals, |scientific |basis |of |study, |and |review |of |relevant
|literature |and |all |procedures |to |be |performed
What |is |the |difference |between |NIH |& |NSF?
✓ ~~~NIH: |primary |granting |agency: |academia, |federal |agencies, |biomedical |research
NSF: |Basic |research |in |math, |medicine, |and |biology
The |USDA |stands |for |what?
✓ ~~~United |States |Department |of |Agriculture
The |USDA |is |responsible |for |what?
✓ ~~~Enforces |and |amends |AWA
Auction, |sale, |exhibit, |transport, |breeding, |or |conduct |of |research |with |animals
Animals |exempt |from |AWA
Research |institutions |mst |register |with
Supply |annual |reports
Inspection |records |through |the |FOIA
,Unscheduled |inspection |once |per |year
What |does |the |FOIA |stand |for?
✓ ~~~Freedom |of |Information |Act |- |provides |the |USDA's |inspection |records
What |is |the |Public |Health |Service |Policy?
✓ ~~~Institutions |which |receive |funding |from |PHS |and |NIH |must |follow |these |guidelines,
|requires |filing |of |an |Amimal |Welfare |Assurance |document |that |demonstrates |the
|institution |is |following |the |Guid, |PHS |policy, |AWA, |and |any |other |applicable |laws
The |FDA |has |many |responsibilites |including:
✓ ~~~Assures |that |new |drugs |and |medical |devices |are |safe |and |effective |before |approved
|for |use |in |humans
Monitors |drug |approval
Includes |human, |and |veterinary |drugs, |food, |and |medical |devices
Requires |that |effectiveness |be |demonstrated |through |well |controlled |investigations
What |is |GLP?
✓ ~~~Good |Laboratory |Practices
Established |in |1978 |with |implementation |of |laboratory |audits |and |inspection
programs
Details |requirements |for |QA |and |SOPs
What |is |the |importance |of |importation |and |transportations |regulations?
, ✓ ~~~For |the |protection |of |humans |and |environment |from |potential |disease |carrying
|organisms
Which |agencies |control |importation?
✓ ~~~CDC, |USDA, |and |US |Fish |& |Wildlife |Service
Institutional |polices |are |established |for:
✓ ~~~facility |operations
care |and |use |procedures
veterinary |support
physical |plant
Standard |operating |procedures |relate |to:
✓ ~~~wall |aspects |of |animal |care |and |support
personnel |management
health |surveillance |of |animals |and |personnel
equipment
investigators
What |are |the |functions |of |IACUCs |and |who |mandates?
✓ ~~~mandated |by |AWA, |PHS |policy, |and |the |Guide
Review |and |approve |protocols |for |animal |use
Review |animal |use |program |and |perform |animal |facilities |inspections |at |least |every |6
months
, What |has |to |happen |before |animal |research |can |begin?
✓ ~~~principal |investigator |provides |written |details |of |how |animals |will |be |used |in |the
|research |project
IACUC |must |review |all |protocols |using |animals |and |must |approve |all |protocols
before |any |animal |research |can |begin
What |does |the |IACUC |determine?
✓ ~~~Can |deny |permission |ro |start |a |project
can |stop |a |research |peoject
Ensures |compliance |with |regulations
Reviews |complete |protocols |at |least |every |3 |years; |reviews |updates |to |protocols
yearly
What |is |the |AAALAC, |International?
✓ ~~~Association |for |Assessment |and |Accreditation |of |Laboratory |Animal |Care,
|International
Non-profit |organization |that |provides |a |mechanism |for |peer |review |of |animal |care
and |use |programs |by |scientific |community
Detailed |application |with |information |on |facilities, |procedures, |programs, |and
research |animals |to |use
Annual |report |must |be |submitted |to |AAALAC |on |status |of |animal |care |program
Site |inspection |and |program |evaluation |every |3 |years
Questions and Answers
U.S. |Government |provides |approximately |how |much |in |research/development |funds
|
spent |by |college |and |university?
✓ ~~~2/3
What |information |is |important |on |grant |applications |to |request |funds?
✓ ~~~Detailed |description |of |research |goals, |scientific |basis |of |study, |and |review |of |relevant
|literature |and |all |procedures |to |be |performed
What |is |the |difference |between |NIH |& |NSF?
✓ ~~~NIH: |primary |granting |agency: |academia, |federal |agencies, |biomedical |research
NSF: |Basic |research |in |math, |medicine, |and |biology
The |USDA |stands |for |what?
✓ ~~~United |States |Department |of |Agriculture
The |USDA |is |responsible |for |what?
✓ ~~~Enforces |and |amends |AWA
Auction, |sale, |exhibit, |transport, |breeding, |or |conduct |of |research |with |animals
Animals |exempt |from |AWA
Research |institutions |mst |register |with
Supply |annual |reports
Inspection |records |through |the |FOIA
,Unscheduled |inspection |once |per |year
What |does |the |FOIA |stand |for?
✓ ~~~Freedom |of |Information |Act |- |provides |the |USDA's |inspection |records
What |is |the |Public |Health |Service |Policy?
✓ ~~~Institutions |which |receive |funding |from |PHS |and |NIH |must |follow |these |guidelines,
|requires |filing |of |an |Amimal |Welfare |Assurance |document |that |demonstrates |the
|institution |is |following |the |Guid, |PHS |policy, |AWA, |and |any |other |applicable |laws
The |FDA |has |many |responsibilites |including:
✓ ~~~Assures |that |new |drugs |and |medical |devices |are |safe |and |effective |before |approved
|for |use |in |humans
Monitors |drug |approval
Includes |human, |and |veterinary |drugs, |food, |and |medical |devices
Requires |that |effectiveness |be |demonstrated |through |well |controlled |investigations
What |is |GLP?
✓ ~~~Good |Laboratory |Practices
Established |in |1978 |with |implementation |of |laboratory |audits |and |inspection
programs
Details |requirements |for |QA |and |SOPs
What |is |the |importance |of |importation |and |transportations |regulations?
, ✓ ~~~For |the |protection |of |humans |and |environment |from |potential |disease |carrying
|organisms
Which |agencies |control |importation?
✓ ~~~CDC, |USDA, |and |US |Fish |& |Wildlife |Service
Institutional |polices |are |established |for:
✓ ~~~facility |operations
care |and |use |procedures
veterinary |support
physical |plant
Standard |operating |procedures |relate |to:
✓ ~~~wall |aspects |of |animal |care |and |support
personnel |management
health |surveillance |of |animals |and |personnel
equipment
investigators
What |are |the |functions |of |IACUCs |and |who |mandates?
✓ ~~~mandated |by |AWA, |PHS |policy, |and |the |Guide
Review |and |approve |protocols |for |animal |use
Review |animal |use |program |and |perform |animal |facilities |inspections |at |least |every |6
months
, What |has |to |happen |before |animal |research |can |begin?
✓ ~~~principal |investigator |provides |written |details |of |how |animals |will |be |used |in |the
|research |project
IACUC |must |review |all |protocols |using |animals |and |must |approve |all |protocols
before |any |animal |research |can |begin
What |does |the |IACUC |determine?
✓ ~~~Can |deny |permission |ro |start |a |project
can |stop |a |research |peoject
Ensures |compliance |with |regulations
Reviews |complete |protocols |at |least |every |3 |years; |reviews |updates |to |protocols
yearly
What |is |the |AAALAC, |International?
✓ ~~~Association |for |Assessment |and |Accreditation |of |Laboratory |Animal |Care,
|International
Non-profit |organization |that |provides |a |mechanism |for |peer |review |of |animal |care
and |use |programs |by |scientific |community
Detailed |application |with |information |on |facilities, |procedures, |programs, |and
research |animals |to |use
Annual |report |must |be |submitted |to |AAALAC |on |status |of |animal |care |program
Site |inspection |and |program |evaluation |every |3 |years
