Test Bank
Clayton’s Basic Pharmacology for Nurses
Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton
19th Edition
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 2
Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and
Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed by
the FDA. The brand name, or trademark, is the name given
to a drug by its manufacturer. The nonproprietary, or generic,
name is provided by the United States Adopted Names
Council.
DIF: Cognitive Level: Knowledge REF: p. 9
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
Environment TOP: Nursing Process Step: Assessment CON:
Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
compilation of drug names, pronunciation guide, and possible future FDA approved
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
Database contains
evidence-based information on herbal medicines and herbal combination products; it
does not include information specific to nutritional supplements. Drug Interaction Facts
contains comprehensive information on drug interaction facts; it does not include
nutritional supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
a. Drug Facts and Comparisons
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
ANS: A
Drug Facts and Comparisons contains drug monographs that describe all drugs
in a therapeutic class. Monographs are formatted as tables to allow comparison
of similar products, brand names, manufacturers, cost indices, and available
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 3
dosage forms Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which drug reference contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including
approved and unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS: B
AHFS Drug Information contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including
approved and unapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public
a standard, comprehensive, up-to-date look up and downloadable resource about
medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS: C
DailyMed makes available to healthcare providers and the public a standard,
comprehensive, up-to-date look up and downloadable resource about medicines. The
American Drug Index is not appropriate for patient use. The American Hospital
Formulary is not appropriate for patient use. The drug reference is not appropriate for
patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA
control and ensure drug safety. The Durham Humphrey Amendment defines the kinds
of drugs that cannot be used safely without medical supervision and restricts their sale
to prescription by a licensed practitioner. The Controlled Substances Act addresses only
controlled substances and their categorization. The Kefauver Harris Drug Amendment
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove
to the FDA the effectiveness of their products before marketing them.
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 4
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Which classification does meperidine (Demerol) fall under?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
lead to severe psychological and physical dependence. Schedule I drugs have high
potential for abuse and no recognized medical use. Schedule III drugs have some
potential for abuse. Use may lead to low to moderate physical dependence or high
psychological dependence. Schedule IV drugs have low potential for abuse. Use may
lead to limited physical or psychological dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and approval for an
outbreak of smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak
would become a priority concern in the world. Orphan diseases are not researched in a
priority manner. Preclinical research is not omitted. Extending any phase of the
research would mean a longer time to develop a vaccine. The FDA must ensure that all
phases of the preclinical and clinical research phase have been completed in a safe
manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment
CON: Health Care Law | Health Care Policy | Infection | Care Coordination
9. Which statement is true about over-the-counter (OTC) drugs?
a. They are not listed in the USP NF.
b. A prescription from a healthcare provider is needed.
c. They are sold without a prescription.
d. They are known only by their brand names.
ANS: C
OTC medications do not require a prescription. A variety of names, both generic and
trade, can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF.
Prescription drugs require an order by a health professional who is licensed to
prescribe, such as a physician, nurse practitioner, physician assistant, or dentist.
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Patient Education
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 5
10. Which is the most authoritative reference for medications that are injected?
a. Martindale: The Complete
b. Handbook on Injectable Drugs
c. DailyMed
d. Handbook of Nonprescription Drugs
ANS: B
The Handbook on Injectable Drugs is the most comprehensive reference available on the
topic of compatibility of injectable drugs. It is a collection of monographs for more than
300 injectable drugs that are listed alphabetically by generic name.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
11. Which statement is true about
Lomotil?
a. Abuse potential for this drug is low.
b. Psychological dependency is likely.
c. There is a high potential for abuse.
d. This drug is not a controlled substance.
ANS: A
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
dependence liability compared with drugs in Schedule IV. Because abuse potential is low
with a Schedule V drug, a prescription may not be required. Psychological dependency is
not likely with a Schedule V drug. Schedule V drugs are classified as controlled
substances.
DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety | Patient Education
12. Which medication ordered for a patient with a substance abuse history has the greatest
risk for abuse?
a. Lomotil
b. Diazepam
c. Phenobarbital
d. Lortab
ANS: D
Lortab is a Schedule III drug with a high potential for abuse but less so than drugs in
Schedules I and II. Lomotil is a Schedule V drug with a low potential for abuse compared
with those in Schedule V. Diazepam is a Schedule IV drug with a low potential for abuse
compared with those in schedule III. Phenobarbital is a Schedule IV drug with a low
potential for abuse compared with those in Schedule III.
DIF: Cognitive Level: Application REF: p. 5 Box 1.1 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Addiction | Patient Education | Safety
13. An older adult experiencing shortness of breath is brought to the hospital by her
daughter. While obtaining the medication history from the patient and her daughter, the
nurse discovers that neither has a list of the patient‘s current medications or
prescriptions. The patient has is a weekly pill dispenser that contains four different
pills. The prescriptions are filled through the local pharmacy. Which resource would be
appropriate to use in determining the medication names and doses?
a. Martindale—The Complete Drug Reference
b. Drugs and Facts Comparisons
Clayton’s Basic Pharmacology for Nurses
Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton
19th Edition
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 2
Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and
Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed by
the FDA. The brand name, or trademark, is the name given
to a drug by its manufacturer. The nonproprietary, or generic,
name is provided by the United States Adopted Names
Council.
DIF: Cognitive Level: Knowledge REF: p. 9
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
Environment TOP: Nursing Process Step: Assessment CON:
Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
compilation of drug names, pronunciation guide, and possible future FDA approved
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
Database contains
evidence-based information on herbal medicines and herbal combination products; it
does not include information specific to nutritional supplements. Drug Interaction Facts
contains comprehensive information on drug interaction facts; it does not include
nutritional supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
a. Drug Facts and Comparisons
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
ANS: A
Drug Facts and Comparisons contains drug monographs that describe all drugs
in a therapeutic class. Monographs are formatted as tables to allow comparison
of similar products, brand names, manufacturers, cost indices, and available
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 3
dosage forms Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. Which drug reference contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including
approved and unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS: B
AHFS Drug Information contains monographs about virtually every single-entity drug
available in the United States and describes therapeutic uses of drugs, including
approved and unapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public
a standard, comprehensive, up-to-date look up and downloadable resource about
medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS: C
DailyMed makes available to healthcare providers and the public a standard,
comprehensive, up-to-date look up and downloadable resource about medicines. The
American Drug Index is not appropriate for patient use. The American Hospital
Formulary is not appropriate for patient use. The drug reference is not appropriate for
patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
safety of all drugs before marketing. Later amendments and acts helped tighten FDA
control and ensure drug safety. The Durham Humphrey Amendment defines the kinds
of drugs that cannot be used safely without medical supervision and restricts their sale
to prescription by a licensed practitioner. The Controlled Substances Act addresses only
controlled substances and their categorization. The Kefauver Harris Drug Amendment
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove
to the FDA the effectiveness of their products before marketing them.
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 4
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Which classification does meperidine (Demerol) fall under?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
lead to severe psychological and physical dependence. Schedule I drugs have high
potential for abuse and no recognized medical use. Schedule III drugs have some
potential for abuse. Use may lead to low to moderate physical dependence or high
psychological dependence. Schedule IV drugs have low potential for abuse. Use may
lead to limited physical or psychological dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and approval for an
outbreak of smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Once the Investigational New Drug Application has been approved, the drug can receive
highest priority within the agency, which is called fast tracking. A smallpox outbreak
would become a priority concern in the world. Orphan diseases are not researched in a
priority manner. Preclinical research is not omitted. Extending any phase of the
research would mean a longer time to develop a vaccine. The FDA must ensure that all
phases of the preclinical and clinical research phase have been completed in a safe
manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment
CON: Health Care Law | Health Care Policy | Infection | Care Coordination
9. Which statement is true about over-the-counter (OTC) drugs?
a. They are not listed in the USP NF.
b. A prescription from a healthcare provider is needed.
c. They are sold without a prescription.
d. They are known only by their brand names.
ANS: C
OTC medications do not require a prescription. A variety of names, both generic and
trade, can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF.
Prescription drugs require an order by a health professional who is licensed to
prescribe, such as a physician, nurse practitioner, physician assistant, or dentist.
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Patient Education
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 5
10. Which is the most authoritative reference for medications that are injected?
a. Martindale: The Complete
b. Handbook on Injectable Drugs
c. DailyMed
d. Handbook of Nonprescription Drugs
ANS: B
The Handbook on Injectable Drugs is the most comprehensive reference available on the
topic of compatibility of injectable drugs. It is a collection of monographs for more than
300 injectable drugs that are listed alphabetically by generic name.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
11. Which statement is true about
Lomotil?
a. Abuse potential for this drug is low.
b. Psychological dependency is likely.
c. There is a high potential for abuse.
d. This drug is not a controlled substance.
ANS: A
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
dependence liability compared with drugs in Schedule IV. Because abuse potential is low
with a Schedule V drug, a prescription may not be required. Psychological dependency is
not likely with a Schedule V drug. Schedule V drugs are classified as controlled
substances.
DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety | Patient Education
12. Which medication ordered for a patient with a substance abuse history has the greatest
risk for abuse?
a. Lomotil
b. Diazepam
c. Phenobarbital
d. Lortab
ANS: D
Lortab is a Schedule III drug with a high potential for abuse but less so than drugs in
Schedules I and II. Lomotil is a Schedule V drug with a low potential for abuse compared
with those in Schedule V. Diazepam is a Schedule IV drug with a low potential for abuse
compared with those in schedule III. Phenobarbital is a Schedule IV drug with a low
potential for abuse compared with those in Schedule III.
DIF: Cognitive Level: Application REF: p. 5 Box 1.1 OBJ: 2
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Addiction | Patient Education | Safety
13. An older adult experiencing shortness of breath is brought to the hospital by her
daughter. While obtaining the medication history from the patient and her daughter, the
nurse discovers that neither has a list of the patient‘s current medications or
prescriptions. The patient has is a weekly pill dispenser that contains four different
pills. The prescriptions are filled through the local pharmacy. Which resource would be
appropriate to use in determining the medication names and doses?
a. Martindale—The Complete Drug Reference
b. Drugs and Facts Comparisons
