Famotidine
-take 30 minutes before you dine
-cimetidine
-used for duodenal ulcers, GERD, heartburn
Famotidine pt teaching
smoking decreases effectiveness & delays healing
avoid alcohol
spicy foods
NSAIDs
increase fiber & fluid
Famotidine CI
pregnancy
older adults - reduced dose, higher risk for CNS effects
kidney impairment- reduced dosage
Cimetidine
increases levels of warfarin, phenytoin, theophylline, and lidocaine
Metoclopramide AE
Prokinetic agent:
- tardive dyskinesia
- EPS
- sedation
- report major lip smacking
- anticholinergic effects
Metoclopramide admin:
- monitor for CNS depression & EPS
- if IV dose is 10 mg or less: IVP undiluted over 2 min, if IV dose > 10 mg: dilute & infuse
over 15 min, dilute in 50 mL D5W, NS, or Lactated Ringer's
Metoclopramide post op
N/V & gastroparesis
Meds for hyperemesis
- ondansetron
- promethazine
, - Dexamethasone + Aprepitant
- Scopolamine
ondansetron
QT prolongation
Serotonin syndrome
Headache/ dizziness
Diarrhea
- do not mix with SSRI, SNRI
promethazine
EPS
crosses BBB
sedation
not for Parkinson pt.)
Dexamethasone + Aprepitant
for N/V for chemo
- report black tarry stools
Can give IM 2 in 24 hours for moms having a baby
Therapeutic effectiveness of nausea meds
prevents emesis
*may need more than 1
Antiemetic patient education
- avoid sedatives opioids, & alcohol
- sit or lie down if lightheadedness or dizziness occurs
- combining 3 is more beneficial
Antiemetic admin:
if used to prevent give 1 hr to 30 min before treatment
H Pylori infection treatment
- burp smells like feces
-combination of two or three antibiotics for 14 days to increase effectiveness & minimize
development of medication resistance
H Pylori Bismuth
PPI + Metronidazole, Tetracycline, Bismuth subsalicylate
H Pylori Non- Bismuth types
PPI + Clarithromycin, Amoxicillin, Metronidazole
H Pylori Non- Bismuth