NR507 Midterm Exam
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Terms in this set (183)
Innate immunity the immunity we are born with
, 1st line: physical, mechanical, & biochemical
barriers
Immune response: 3
levels/lines of
2nd line: the inflammatory response
protection
3rd line: lymphocyte production
most important intact skin and mucous membranes
immune defense (impermeable barrier)
pathogen associated molecular pattern
surfaces of bacteria, viruses, and other
PAMP microbes are covered with many foreign
proteins
foreign
, damage associated molecular pattern
many proteins are released from inside our
DAMP
cells when they are damaged
foreign
pattern recognition receptors
surfaces of WBCs contain these receptor sites
PRR
-continuously interact with any material they
encounter to ID it as "self" or "non-self"
(foreign; PAMP or DAMP)
Cell movement that occurs in response to
Chemotaxis
chemical stimulus
, "cell eating"
1. opsonization and adherence
2. engulfment - WBC surrounds and ingests Ag
3. Fusion of phagosome with lysosome
Phagocytosis
4. destruction - phagosome digested by
lysozyme, H202, acids, and other toxic
chemicals inside the lysosomes
5. egestion
Hypersensitivity Type Allergic reaction
1:_____
Hypersensitivity: Type IgE
1
Mediated by ______
Hypersensitivity: Type mast cell degranulation
1
Inflammation due to
_____________
Save
Terms in this set (183)
Innate immunity the immunity we are born with
, 1st line: physical, mechanical, & biochemical
barriers
Immune response: 3
levels/lines of
2nd line: the inflammatory response
protection
3rd line: lymphocyte production
most important intact skin and mucous membranes
immune defense (impermeable barrier)
pathogen associated molecular pattern
surfaces of bacteria, viruses, and other
PAMP microbes are covered with many foreign
proteins
foreign
, damage associated molecular pattern
many proteins are released from inside our
DAMP
cells when they are damaged
foreign
pattern recognition receptors
surfaces of WBCs contain these receptor sites
PRR
-continuously interact with any material they
encounter to ID it as "self" or "non-self"
(foreign; PAMP or DAMP)
Cell movement that occurs in response to
Chemotaxis
chemical stimulus
, "cell eating"
1. opsonization and adherence
2. engulfment - WBC surrounds and ingests Ag
3. Fusion of phagosome with lysosome
Phagocytosis
4. destruction - phagosome digested by
lysozyme, H202, acids, and other toxic
chemicals inside the lysosomes
5. egestion
Hypersensitivity Type Allergic reaction
1:_____
Hypersensitivity: Type IgE
1
Mediated by ______
Hypersensitivity: Type mast cell degranulation
1
Inflammation due to
_____________
