2026/ 2027 Update) 100% Verified
Questions & Answers | Grade A
define potency -- correct answer r •Dose required to produce the desired
biologic response
define efficacy -- correct answer r •Ability of a drug to produce a desired
response
define toxicity -- correct answer r •refers to the point at which
concentrations of the drug in the bloodstream become harmful or
poisonous to the body.
define high therapeutic index -- correct answer r -there is a wide range
between dose at which the drug begins to take effect and dose that would
be considered toxic.
define pharmacokinetics -- correct answer r •How a drug moves
throughout the body to get to its target receptors and then is eliminated.
, NURS306 Final Exam – OB | WCU (Latest
2026/ 2027 Update) 100% Verified
Questions & Answers | Grade A
define bioavailability -- correct answer r •Amount of drug that reaches
systemic circulation unchanged
•Often used to compare one drug to another—usually the higher the
bioavailability, the better
which metabolic enzyme is most responsible for drug metabolism? --
correct answer r Cytochrome P-450
where is most metabolism carried out? -- correct answer r liver
T/F psychiatric drugs must pass through the blood-brain barrier -- correct
answer r true
what factors affect distribution of a drug? -- correct answer r -Amount of
blood flow or perfusion within the tissue how lipophilic ("fat-loving") the
drug is; plasma protein binding; and anatomic barriers, such as the blood-
brain barrier, that the drug must cross
, NURS306 Final Exam – OB | WCU (Latest
2026/ 2027 Update) 100% Verified
Questions & Answers | Grade A
define half life -- correct answer r •refers to the time required for plasma
concentrations of the drug to be reduced by 50%.
describe SSRIs -- correct answer r - class of compounds typically used as
antidepressants in the treatment of major depressive disorder and anxiety
disorders
- believed to increase the extracellular level of the neurotransmitter
serotonin by inhibiting its re-uptake into the presynaptic cell
what are the phases of drug treatment? -- correct answer r initiation,
stabilization, maintenance and discontinuation
•The amount of drug that reaches systemic circulation unchanged is
known as the drug's__________________. -- correct answer r •Bioavailability
define positive symptoms -- correct answer r •Excess distortion of normal
function
-Hallucination (mostly auditory)
-Delusions (disordered thoughts or speech)
, NURS306 Final Exam – OB | WCU (Latest
2026/ 2027 Update) 100% Verified
Questions & Answers | Grade A
-Paranoia
define negative symptoms -- correct answer r •A decrease or complete
loss to emotional respond to people and events.
-Decrease in speaking (alogia)
-Flat emotional levels
-Inappropriate social responses to normal social cues
which type of antipsychotic has less side effects - typical or atypical --
correct answer r atypical antipsychotics (unconventional)
Define Extrapyramidal symptoms. -- correct answer r drug-induced
movement disorders such as. akathisia (restlessness), parkinsonism &
acute dystonia (involuntary muscle contractions)
Define neuroleptic malignant syndrome -- correct answer r is a life-
threatening idiosyncratic reaction to antipsychotic drugs characterized by
fever, altered mental status, muscle rigidity, and autonomic dysfunction