TEST BANK FOR PATHOPHYSIOLOGY 9TH
x6 x6 x6 x6
x6 EDITION McCANCE ALL CHAPTERS 1-50
x6 x6 x6 x6
x6 QUESTIONS & ANSWERS 2025.
x6 x6 x6
,Chapter1-49 6
x
Chapter01: Cellular Biologyx6 x6 x6
Rogers:McCance& Huether’sPathophysiology, 9thEdition
6
x x6 x6 x6 x6 6
x
MULTIPLE CHOICE x6
1. Which statement best describes the cellular function of metabolic absorption?
x6 x6 x6 x6 x6 x6 x6 x6 x6
a. Cells can produce proteins. x6 x6 x6
b. Cells can secrete digestive x6 x6 x6
enzymes. x6
c. Cells can take in and use x6 x6 x6 x6 x6
nutrients. x6
d. Cells can synthesize fats. x6 x6 x6
ANS: x 6 C
In metabolic absorption, all cells take in and use nutrients and other substances
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
from their surroundings. The remaining options are not inclusive in their
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
descriptions of cellular metabolic absorption.
x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
2. Whereis most of a cell’s genetic information, including RNA and DNA, contained?
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
a. Mitochond
ria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: x 6 C
The nucleus contains the nucleolus, a small dense structure composed largely
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
of RNA, most of the cellular DNA, and the DNA-binding proteins, such as the
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
histones, which regulate its activity. The mitochondria are responsible for
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
cellular respiration and energy production.
x6 x6 x6 x6 x6
Ribosomes’ chieffunction is to provide sites for cellularprotein synthesis. x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
Lysosomes function as the intracellular digestive system.
x6 x6 x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
3. Which component of the cell produces hydrogen peroxide (H2O2) byusing
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
oxygen to remove hydrogen atoms from specific substrates in an oxidative
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
reaction?
x6
a. Lysosome
s
b. Peroxisom
es
c. Ribosome
, s
d. Endosome
ANS: x 6 B
, Peroxisomes are so named because they usually contain enzymes that use oxygen to
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
remove hydrogen atoms from specific substrates in an oxidative reaction that produces
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
H2O2, which is a powerful oxidant and potentially destructive if it accumulates or
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
escapes from peroxisomes. Ribosomes are RNA-protein complexes (nucleoproteins)
x6 x6 x6 x6 x6 x6 x6 x6
that are synthesized in the nucleolus and secreted into the cytoplasm through pores in
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
the nuclear envelope called nuclear pore complexes. Lysosomes are saclike structures
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
that originate from the Golgi complex and contain more than 40 digestive enzymes
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
carbohydrates. An endosome is a vesical that has been pinched off from the cellular
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
membrane.
x6
DIF: Cognitive Level: Remembering x6 x6
4. Which cell component is capable of cellular autodigestion when it is
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
released during cell injury?
x6 x6 x6 x6
a. Ribosome
b. Golgi complex x6
c. Smooth endoplasmic x6
reticulum
x6
d. Lysosomes
ANS: x 6 D
Thelysosomal membrane acts as a protective shield between the powerful
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
digestive enzymes within the lysosome and the cytoplasm, preventing their
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
leakage into the cytoplasmic matrix. Disruption of the membrane by various
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
treatments or cellular injury leads to a release of the lysosomal enzymes,
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
which can then react with their specific substrates, causing cellular self-
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
digestion. The chief function of a ribosome is to provide sites for cellular
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
protein synthesis. The Golgi complex is a network of flattened, smooth
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
vesicles and membranes often located near the cell nucleus. The smooth
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
endoplasmic reticulum is involved in steroid hormone production and
x6 x6 x6 x6 x6 x6 x6 x6 x6
removing toxic substances from the cell.
x6 x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
5. Which cAMP-mediated response is related to antidiuretic hormone?
x6 x6 x6 x6 x6 x6 x6
a. Increased heart rate and force of x6 x6 x6 x6 x6
contraction
x6
b. Secretion of cortisol x6 x6
c. Increased retention of water x6 x6 x6
d. Breakdown of fat x6 x6
ANS: x 6 C
Antidiuretic hormone leads to increased retention of water in the body. x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
Epinephrine causes increases in heart rate and force of contraction. Increased
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
cortisol secretion is due to ACTH. Breakdown of fat is due to glucagon.
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
6. During which phase of the cell cycle is DNA synthesized?
x6 x6 x6 x6 x6 x6 x6 x6 x6
x6 x6 x6 x6
x6 EDITION McCANCE ALL CHAPTERS 1-50
x6 x6 x6 x6
x6 QUESTIONS & ANSWERS 2025.
x6 x6 x6
,Chapter1-49 6
x
Chapter01: Cellular Biologyx6 x6 x6
Rogers:McCance& Huether’sPathophysiology, 9thEdition
6
x x6 x6 x6 x6 6
x
MULTIPLE CHOICE x6
1. Which statement best describes the cellular function of metabolic absorption?
x6 x6 x6 x6 x6 x6 x6 x6 x6
a. Cells can produce proteins. x6 x6 x6
b. Cells can secrete digestive x6 x6 x6
enzymes. x6
c. Cells can take in and use x6 x6 x6 x6 x6
nutrients. x6
d. Cells can synthesize fats. x6 x6 x6
ANS: x 6 C
In metabolic absorption, all cells take in and use nutrients and other substances
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
from their surroundings. The remaining options are not inclusive in their
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
descriptions of cellular metabolic absorption.
x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
2. Whereis most of a cell’s genetic information, including RNA and DNA, contained?
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
a. Mitochond
ria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: x 6 C
The nucleus contains the nucleolus, a small dense structure composed largely
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
of RNA, most of the cellular DNA, and the DNA-binding proteins, such as the
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
histones, which regulate its activity. The mitochondria are responsible for
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
cellular respiration and energy production.
x6 x6 x6 x6 x6
Ribosomes’ chieffunction is to provide sites for cellularprotein synthesis. x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
Lysosomes function as the intracellular digestive system.
x6 x6 x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
3. Which component of the cell produces hydrogen peroxide (H2O2) byusing
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
oxygen to remove hydrogen atoms from specific substrates in an oxidative
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
reaction?
x6
a. Lysosome
s
b. Peroxisom
es
c. Ribosome
, s
d. Endosome
ANS: x 6 B
, Peroxisomes are so named because they usually contain enzymes that use oxygen to
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
remove hydrogen atoms from specific substrates in an oxidative reaction that produces
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
H2O2, which is a powerful oxidant and potentially destructive if it accumulates or
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
escapes from peroxisomes. Ribosomes are RNA-protein complexes (nucleoproteins)
x6 x6 x6 x6 x6 x6 x6 x6
that are synthesized in the nucleolus and secreted into the cytoplasm through pores in
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
the nuclear envelope called nuclear pore complexes. Lysosomes are saclike structures
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
that originate from the Golgi complex and contain more than 40 digestive enzymes
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
carbohydrates. An endosome is a vesical that has been pinched off from the cellular
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
membrane.
x6
DIF: Cognitive Level: Remembering x6 x6
4. Which cell component is capable of cellular autodigestion when it is
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
released during cell injury?
x6 x6 x6 x6
a. Ribosome
b. Golgi complex x6
c. Smooth endoplasmic x6
reticulum
x6
d. Lysosomes
ANS: x 6 D
Thelysosomal membrane acts as a protective shield between the powerful
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
digestive enzymes within the lysosome and the cytoplasm, preventing their
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
leakage into the cytoplasmic matrix. Disruption of the membrane by various
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
treatments or cellular injury leads to a release of the lysosomal enzymes,
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
which can then react with their specific substrates, causing cellular self-
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
digestion. The chief function of a ribosome is to provide sites for cellular
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
protein synthesis. The Golgi complex is a network of flattened, smooth
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
vesicles and membranes often located near the cell nucleus. The smooth
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
endoplasmic reticulum is involved in steroid hormone production and
x6 x6 x6 x6 x6 x6 x6 x6 x6
removing toxic substances from the cell.
x6 x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
5. Which cAMP-mediated response is related to antidiuretic hormone?
x6 x6 x6 x6 x6 x6 x6
a. Increased heart rate and force of x6 x6 x6 x6 x6
contraction
x6
b. Secretion of cortisol x6 x6
c. Increased retention of water x6 x6 x6
d. Breakdown of fat x6 x6
ANS: x 6 C
Antidiuretic hormone leads to increased retention of water in the body. x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
Epinephrine causes increases in heart rate and force of contraction. Increased
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
cortisol secretion is due to ACTH. Breakdown of fat is due to glucagon.
x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6 x6
DIF: Cognitive Level: Remembering x6 x6
6. During which phase of the cell cycle is DNA synthesized?
x6 x6 x6 x6 x6 x6 x6 x6 x6
