NSG5003 WEEK 3 EXAM QUESTIONS
WITH 100% CORRECT ANSWERS
LATEST VERSION 2025/2026.
Inserting bone marrow cells into an individual who produces abnormal erythrocytes is an
example of what type of therapy? - ANS Somatic cell
DNA replication requires the enzyme DNA polymerase to: - ANS Travel along the single DNA
strand, adding the correct nucleotide to the new strand
Transcription is best defined as a process by which: - ANS RNA is synthesized from a DNA
template.
The purpose of a staining technique of chromosomes such as Giemsa is to: - ANS Allow for
the numbering of chromosomes and the identification of variations.
An amniocentesis indicates a neural tube defect when an increase in which protein is evident? -
ANS Alpha fetoprotein
An amniocentesis is recommended for pregnant women who: - ANS Have a family history of
genetic disorders
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,The most clinically useful technique for prenatal diagnosis of chromosomal abnormalities at 3
months' (12 weeks') gestation is: - ANS Chorionic villus sampling
The term for an error in which homologous chromosomes fail to separate during meiosis or
mitosis is: - ANS Nondisjunction
Which clinical manifestations would be expected for a child who has complete trisomy of the
twenty-first chromosome? - ANS An IQ of 25 to 70, low nasal bridge, protruding tongue, and
flat, low-set ears
What is the most common cause of Down syndrome? - ANS Maternal nondisjunction
What syndrome, characterized by an absent homologous X chromosome with only a single X
chromosome, exhibits features that include a short stature, widely spaced nipples, and webbed
neck? - ANS Cri du chat
A person with 47, XXY karyotype has the genetic disorder resulting in which syndrome? -
ANS Klinefelter
What is the chromosomal variation that causes Klinefelter syndrome? - ANS Nondisjunction
of X chromosome in the mother
What is the second most commonly recognized genetic cause of mental retardation? -
ANS Fragile X syndrome
What is the blood type of a person who is heterozygous, having A and B alleles as codominant? -
ANS AB
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, A couple has two children diagnosed with an autosomal dominant genetic disease. What is the
probability that the next child will have the same genetic disease? - ANS One half
When a child inherits a disease that is autosomal recessive, it is inherited from: - ANS Both
parents
People diagnosed with neurofibromatosis have varying degrees of the condition because of the
genetic principle of: - ANS Expressivity
Which genetic disease has been linked to a mutation of the tumor-suppressor gene? -
ANS Retinoblastoma
Cystic fibrosis is caused by what type of gene? - ANS Autosomal recessive
Which is an important criterion for discerning autosomal recessive inheritance? -
ANS Consanguinity is sometimes present.
Consanguinity refers to the mating of persons: - ANS Having common family relations
Males, having only one X chromosome (as is expected), are said to be: - ANS Hemizygous
Males are more often affected by which type of genetic disease? - ANS Sex-linked recessive
An X-linked recessive disease can skip generations because: - ANS The disease can be
transmitted through female carriers.
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
WITH 100% CORRECT ANSWERS
LATEST VERSION 2025/2026.
Inserting bone marrow cells into an individual who produces abnormal erythrocytes is an
example of what type of therapy? - ANS Somatic cell
DNA replication requires the enzyme DNA polymerase to: - ANS Travel along the single DNA
strand, adding the correct nucleotide to the new strand
Transcription is best defined as a process by which: - ANS RNA is synthesized from a DNA
template.
The purpose of a staining technique of chromosomes such as Giemsa is to: - ANS Allow for
the numbering of chromosomes and the identification of variations.
An amniocentesis indicates a neural tube defect when an increase in which protein is evident? -
ANS Alpha fetoprotein
An amniocentesis is recommended for pregnant women who: - ANS Have a family history of
genetic disorders
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,The most clinically useful technique for prenatal diagnosis of chromosomal abnormalities at 3
months' (12 weeks') gestation is: - ANS Chorionic villus sampling
The term for an error in which homologous chromosomes fail to separate during meiosis or
mitosis is: - ANS Nondisjunction
Which clinical manifestations would be expected for a child who has complete trisomy of the
twenty-first chromosome? - ANS An IQ of 25 to 70, low nasal bridge, protruding tongue, and
flat, low-set ears
What is the most common cause of Down syndrome? - ANS Maternal nondisjunction
What syndrome, characterized by an absent homologous X chromosome with only a single X
chromosome, exhibits features that include a short stature, widely spaced nipples, and webbed
neck? - ANS Cri du chat
A person with 47, XXY karyotype has the genetic disorder resulting in which syndrome? -
ANS Klinefelter
What is the chromosomal variation that causes Klinefelter syndrome? - ANS Nondisjunction
of X chromosome in the mother
What is the second most commonly recognized genetic cause of mental retardation? -
ANS Fragile X syndrome
What is the blood type of a person who is heterozygous, having A and B alleles as codominant? -
ANS AB
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, A couple has two children diagnosed with an autosomal dominant genetic disease. What is the
probability that the next child will have the same genetic disease? - ANS One half
When a child inherits a disease that is autosomal recessive, it is inherited from: - ANS Both
parents
People diagnosed with neurofibromatosis have varying degrees of the condition because of the
genetic principle of: - ANS Expressivity
Which genetic disease has been linked to a mutation of the tumor-suppressor gene? -
ANS Retinoblastoma
Cystic fibrosis is caused by what type of gene? - ANS Autosomal recessive
Which is an important criterion for discerning autosomal recessive inheritance? -
ANS Consanguinity is sometimes present.
Consanguinity refers to the mating of persons: - ANS Having common family relations
Males, having only one X chromosome (as is expected), are said to be: - ANS Hemizygous
Males are more often affected by which type of genetic disease? - ANS Sex-linked recessive
An X-linked recessive disease can skip generations because: - ANS The disease can be
transmitted through female carriers.
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
