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1. systemic lupus erythematosus Autoimmune disease in which immune system attacks
(SLE) connective tissue throughout body such as in joints and
skin.
Chronic multisystem inflammatory autoimmune disorder.
2. SLE is more common in: Females (85%)
Higher incidence in young women of color in the US.
3. Common clinical findings with Fatigue, joint pain, rash, seizures, chest pain, vasculitis,
SLE: nephritis, weight loss, fevers, tachycardia, lymphadenopa-
thy
4. discoid lupus erythematosus Rash primarily seen on the face, scalp and trunk. Aggravat-
ed by the sun.
5. Malar butterfly rash seen in: SLE
6. SLE workup may include: CBC, ESR, CRP, Gamma Globulins, ANA, RA, Anti-Smith,
BUN/Creat, 24 hour protein, IgG, IgM, Anti-beta 2 glyco-
protein
7. Lupus nonpharmacologic man- Heart health diet, modest exercise, avoidance of sun
agement:
8. Lupus pharmacologic manage- Omega-3
ment: Steroids
NSAIDS
Hydrochloroquine
Monoclonal Antibody
Immunosuppressants
9. Raynaud's disease
, NURS 600 Exam # 3
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Peripheral arterial occlusive disease in which intermittent
attacks are triggered by cold or stress.
10. Raynaud's Disease Reversible vasospastic disorder that affects the blood flow
to the digits.
11. Raynaud's generally affects: Females
(Often presents 15-45 years of age)
12. _______- Raynaud's Phenome- Primary
non:
No associated autoimmune dis-
ease. No autoantibodies pre-
sent.
13. ______ Raynaud's Phenomenon: Secondary
Associated with an autoim-
mune disease. (SLE, Scleroder-
ma, mixed connective tissue dis-
ease)
14. CREST syndrome ("systemic scle- Calcinosis
rosis") Raynaud's
Esophageal dysmotility
Sclerodactyly (skin tightening on hands)
Telangiectasia (capillary dilation on - red spots on skin)
15. ______ Raynaud's Phenomenon Secondary
may be associated with CREST
syndrome.
16. Migraines, headaches, chest pain
, NURS 600 Exam # 3
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Individual's with Raynaud's Phe-
nomenon may also experience:
(3)
17. Raynaud's Phenomenon may be Drugs, trauma, hematologic disorders, vibrations, frost-
related to: bite, atherosclerotic disease
18. Sharp demarcation where the Pallor --> Cyanosis --> Rubor
spasm occurs.
Tricolor presentation of Ray-
naud's Phenomenon:
___ --> _____ -->_____
19. Raynaud's is often triggered by: Cold exposure or stress
___ or ____
20. Raynaud's vasospasms are: Painful, symmetric and parasthesia
(Generally do not involve the toes)
21. General timeframe for Ray- 20 minutes to hours
naud's vasospasms:
22. Raynaud's workup should in- Clinical history (tricolor vasospasm), capillaroscopy, ANA
clude: (3)
23. Buerger's disease Condition in which the blood vessels, especially those sup-
plying the legs, are constricted whenever nicotine enters
the bloodstream, the ultimate result being gangrene and
amputation.
24. Raynaud's Nonpharmacologic Environmental measures (avoiding cold), keeping the
Management: body warm with clothing, stress management, strict smok-
ing cessation