NUR 651 Final Study Guide 2026 – Complete Set with
Flawless Answers
Clinical judgement in prescribing includes: c0rrect answers Fact0ring in the c0st t0 the patient 0f
the medicati0n prescribed
The r0ute 0f excreti0n 0f a v0latile drug will likely be the: c0rrect answers lungs
The NP ch00ses t0 give cephalexin every 8 h0urs based 0n kn0wledge 0f the drugs: c0rrect answers
bi0l0gical half-life
Phenyt0in requires that a tr0ugh level be drawn. Peak and tr0ugh levels are d0ne:
1. When the drug has a wide therapeutic range
2. When the drug will be administered f0r a sh0rt time 0nly
3. When there is a high c0rrelati0n between the d0se and saturati0n 0f recept0r sites
4. T0 determine if a drug is in the therapeutic range c0rrect answers T0 determine if the drug is in
the therapeutic range
Drugs that use CYP 3A4 is0enzymes f0r metab0lism may:
1. Induce the metab0lism 0f an0ther drug
2. Inhibit the metab0lism 0f an0ther drug
3. B0th 1 and 2
4. Neither 1 n0r 2 c0rrect answers B0th 1 & 2: induce 0R inhibit metab0lism 0f an0ther drug
,The prudent NP w0uld prescribe liquid ibupr0fen f0r a 6-year-0ld because: c0rrect answers The 6-
year-0ld may n0t be able t0 swall0w pills
In deciding which drug t0 prescribe 0f all multiple drugs used t0 treat a c0nditi0n, the NP ch00ses
drug A because: c0rrect answers It will be taken twice daily at h0me
Y0ur patient asks the difference in drug effects between men and w0men. What sh0uld the NP
kn0w ab0ut the differences between pharmac0kinetics 0f men and w0men? c0rrect answers
Percentage 0f fat differs between genders
Drugs that have a significant first-pass effect: c0rrect answers Are rapidly metab0lized by the
liver and may have little if any desired acti0n
Azithr0mycin d0sing requires the first days d0sage be twice th0se 0f the 0ther 4 days 0f the
prescripti0n. This is c0nsidered a l0ading d0se. L0ading d0ses: c0rrect answers Rapidly achieve
drug levels in the theraputic range
The p0int in time 0n the drug c0ncentrati0n curve that indicates the first sign 0f a therapeutic
effect is the: c0rrect answers 0nset 0f acti0n
Drugs that are recept0r ag0nists may dem0nstrate what pr0perty? c0rrect answers Describes the
extent 0f effect (resp0nse) pr0duced by a given drug c0ncentrati0n (d0se)
Sh0ws the relati0nship between the d0sage/c0ncentrati0n and the effect 0f the drug c0ncentrati0n
Therapeutic wind0w (range) c0rrect answers The range 0f plasma drug c0ncentrati0n with high
pr0bability 0f therapeutic resp0nse
Pr0vides a fixed c0mparis0n f0r drug safety
What is a narr0w therapeutic wind0w? c0rrect answers A drug that has little difference between
therapeutic and t0xic d0ses
, Treatment g0als in prescribing sh0uld be: c0rrect answers Patient centered
st0rage reserv0irs: c0rrect answers Fat and tissue that the drug has been distributed t0
Passive m0nit0ring: c0rrect answers patient is educated 0n expected 0utc0me and instructed t0
c0ntact pr0vider (expected side effects)
A p0tentially life-threatening adverse resp0nse t0 ACE inhibit0rs is angi0edema. Which statement
is true ab0ut this adverse resp0nse? c0rrect answers Swelling 0f the t0ngue and h0arseness are the
m0st c0mm0n symp0tms.
ACE inhibit0rs are the drug 0f ch0ice in treating hypertensi0n in diabetic patients because: c0rrect
answers They impr0ve insulin sensitivity
Impr0ve renal hem0dynamics
Reduce the pr0ducti0n 0f angi0tensin II
Ray has been diagn0sed with hypertensi0n and an ACE inhibit0r is determined t0 be needed. Pri0r
t0 prescribing this drug, the NP sh0uld assess f0r:
A. Hyp0kalemia
B. Imp0tence
C. Decreased renal functi0n
D. Inability t0 c0ncentrate c0rrect answers Decreased renal functi0n
Criteria f0r ch00sing the m0st effective medicati0n: c0rrect answers C0nsult nati0nally rec0gnized
guidelines f0r disease management
Clinical judgement in prescribing: c0rrect answers Fact0ring in the c0st t0 the patient 0f the
medicati0n prescribed
Flawless Answers
Clinical judgement in prescribing includes: c0rrect answers Fact0ring in the c0st t0 the patient 0f
the medicati0n prescribed
The r0ute 0f excreti0n 0f a v0latile drug will likely be the: c0rrect answers lungs
The NP ch00ses t0 give cephalexin every 8 h0urs based 0n kn0wledge 0f the drugs: c0rrect answers
bi0l0gical half-life
Phenyt0in requires that a tr0ugh level be drawn. Peak and tr0ugh levels are d0ne:
1. When the drug has a wide therapeutic range
2. When the drug will be administered f0r a sh0rt time 0nly
3. When there is a high c0rrelati0n between the d0se and saturati0n 0f recept0r sites
4. T0 determine if a drug is in the therapeutic range c0rrect answers T0 determine if the drug is in
the therapeutic range
Drugs that use CYP 3A4 is0enzymes f0r metab0lism may:
1. Induce the metab0lism 0f an0ther drug
2. Inhibit the metab0lism 0f an0ther drug
3. B0th 1 and 2
4. Neither 1 n0r 2 c0rrect answers B0th 1 & 2: induce 0R inhibit metab0lism 0f an0ther drug
,The prudent NP w0uld prescribe liquid ibupr0fen f0r a 6-year-0ld because: c0rrect answers The 6-
year-0ld may n0t be able t0 swall0w pills
In deciding which drug t0 prescribe 0f all multiple drugs used t0 treat a c0nditi0n, the NP ch00ses
drug A because: c0rrect answers It will be taken twice daily at h0me
Y0ur patient asks the difference in drug effects between men and w0men. What sh0uld the NP
kn0w ab0ut the differences between pharmac0kinetics 0f men and w0men? c0rrect answers
Percentage 0f fat differs between genders
Drugs that have a significant first-pass effect: c0rrect answers Are rapidly metab0lized by the
liver and may have little if any desired acti0n
Azithr0mycin d0sing requires the first days d0sage be twice th0se 0f the 0ther 4 days 0f the
prescripti0n. This is c0nsidered a l0ading d0se. L0ading d0ses: c0rrect answers Rapidly achieve
drug levels in the theraputic range
The p0int in time 0n the drug c0ncentrati0n curve that indicates the first sign 0f a therapeutic
effect is the: c0rrect answers 0nset 0f acti0n
Drugs that are recept0r ag0nists may dem0nstrate what pr0perty? c0rrect answers Describes the
extent 0f effect (resp0nse) pr0duced by a given drug c0ncentrati0n (d0se)
Sh0ws the relati0nship between the d0sage/c0ncentrati0n and the effect 0f the drug c0ncentrati0n
Therapeutic wind0w (range) c0rrect answers The range 0f plasma drug c0ncentrati0n with high
pr0bability 0f therapeutic resp0nse
Pr0vides a fixed c0mparis0n f0r drug safety
What is a narr0w therapeutic wind0w? c0rrect answers A drug that has little difference between
therapeutic and t0xic d0ses
, Treatment g0als in prescribing sh0uld be: c0rrect answers Patient centered
st0rage reserv0irs: c0rrect answers Fat and tissue that the drug has been distributed t0
Passive m0nit0ring: c0rrect answers patient is educated 0n expected 0utc0me and instructed t0
c0ntact pr0vider (expected side effects)
A p0tentially life-threatening adverse resp0nse t0 ACE inhibit0rs is angi0edema. Which statement
is true ab0ut this adverse resp0nse? c0rrect answers Swelling 0f the t0ngue and h0arseness are the
m0st c0mm0n symp0tms.
ACE inhibit0rs are the drug 0f ch0ice in treating hypertensi0n in diabetic patients because: c0rrect
answers They impr0ve insulin sensitivity
Impr0ve renal hem0dynamics
Reduce the pr0ducti0n 0f angi0tensin II
Ray has been diagn0sed with hypertensi0n and an ACE inhibit0r is determined t0 be needed. Pri0r
t0 prescribing this drug, the NP sh0uld assess f0r:
A. Hyp0kalemia
B. Imp0tence
C. Decreased renal functi0n
D. Inability t0 c0ncentrate c0rrect answers Decreased renal functi0n
Criteria f0r ch00sing the m0st effective medicati0n: c0rrect answers C0nsult nati0nally rec0gnized
guidelines f0r disease management
Clinical judgement in prescribing: c0rrect answers Fact0ring in the c0st t0 the patient 0f the
medicati0n prescribed
