Pharmacology HESI questions and answers
2025\2026 A+ Grade
The nurse reviews the new prescription, phenelzine (Nardil), a monoamine oxidase inhibitor (MAOI), for
a client with depression on the psychiatric unit. Which information is most important for the nurse to
assess?
- correct answer Consumption of any alcohol or tyramine-rich foods.
The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first time. What side effects
should the nurse assess the client for during the initial dose?
- correct answer Dystonia.
While reviewing the client's electronic medical record (EMR), the nurse assesses a client who is at risk
for a possible interaction with an over-the-counter (OTC) decongestant. Which client health history
should the nurse report to the healthcare provider concerning the OTC medication? (Select all that
apply.)
- correct answer Closed angle glaucoma.
Chronic hypertension.
A client prescribed ipratropium reports nausea, blurred vision, headaches, and insomnia after using the
inhaler. Which action should the nurse implement first?
- correct answer Withhold medication and report symptoms and vital signs to healthcare provider.
A client diagnosed with multiple sclerosis is experiencing profound weakness, blurry vision, and shooting
pains in both legs. Which medication is considered the best course of treatment for the nurse to
administer?
- correct answer High dose methylprednisolone intravenously.
The nurse administers 30 mL of lactulose for a client with stage 2 hepatic encephalopathy. Which
assessment finding would indicate the medication is being therapeuitc?
- correct answer A decrease in blood ammonia levels.
, The nurse is teaching a client who is newly diagnosed with Type 1 diabetes about neutral protamine
Hagedor (NPH) insulin. Which statement by the client indicates an understanding of how the medication
works?
- correct answer It facilitates the transport of glucose into the cells.
The nurse should withhold which medication if a client reports nausea, vomiting, and diarrhea?
- correct answer Colchicine (Mitigare, Colcrys).
A client newly prescribed esomeprazole for gastroesophageal reflux disease (GERD) asks the nurse how
the medication will help. Which is the best explanation to provide the client?
- correct answer It will promote rapid tissue healing.
A nurse is providing medication education for a client prescribed a beta-blocking agents for treatment of
glaucoma. Which statement by the client demonstrates an understanding of the mechanism of the
medication?
- correct answer It inhibits the aqueous humor production.
A nurse is planning a teaching session for a client newly prescribed a miotic drug for the treatment of
glaucoma. Which information should the nurse include in the teaching session?
- correct answer The medication enhances the aqueous humor outflow.
The healthcare provider (HCP) prescribes a medication for an older adult client who is reporting
insomnia, and the HCP instructs the client to return in two weeks. The nurse should question which
prescription?
- correct answer Eszopiclone (Lunesta) 10 milligrams orally at bedtime.
A client is diagnosed with peptic ulcer disease and receives a prescription for esomeprazole (Nexium) 20
mg capsule daily. When providing this client with discharge teaching, the nurse should include which
instruction?
- correct answer Take at same time each day one hour before eating a meal.
A client receives a new prescription for ciprofloxacin (Cipro), a synthetic quinolone. When teaching
about this drug, which information in the client's history requires special emphasis by the nurse?
- correct answer Works twenty hours a week as a lifeguard at the local pool.
2025\2026 A+ Grade
The nurse reviews the new prescription, phenelzine (Nardil), a monoamine oxidase inhibitor (MAOI), for
a client with depression on the psychiatric unit. Which information is most important for the nurse to
assess?
- correct answer Consumption of any alcohol or tyramine-rich foods.
The nurse is administering haloperidol 0.5 mg IM PRN to a client for the first time. What side effects
should the nurse assess the client for during the initial dose?
- correct answer Dystonia.
While reviewing the client's electronic medical record (EMR), the nurse assesses a client who is at risk
for a possible interaction with an over-the-counter (OTC) decongestant. Which client health history
should the nurse report to the healthcare provider concerning the OTC medication? (Select all that
apply.)
- correct answer Closed angle glaucoma.
Chronic hypertension.
A client prescribed ipratropium reports nausea, blurred vision, headaches, and insomnia after using the
inhaler. Which action should the nurse implement first?
- correct answer Withhold medication and report symptoms and vital signs to healthcare provider.
A client diagnosed with multiple sclerosis is experiencing profound weakness, blurry vision, and shooting
pains in both legs. Which medication is considered the best course of treatment for the nurse to
administer?
- correct answer High dose methylprednisolone intravenously.
The nurse administers 30 mL of lactulose for a client with stage 2 hepatic encephalopathy. Which
assessment finding would indicate the medication is being therapeuitc?
- correct answer A decrease in blood ammonia levels.
, The nurse is teaching a client who is newly diagnosed with Type 1 diabetes about neutral protamine
Hagedor (NPH) insulin. Which statement by the client indicates an understanding of how the medication
works?
- correct answer It facilitates the transport of glucose into the cells.
The nurse should withhold which medication if a client reports nausea, vomiting, and diarrhea?
- correct answer Colchicine (Mitigare, Colcrys).
A client newly prescribed esomeprazole for gastroesophageal reflux disease (GERD) asks the nurse how
the medication will help. Which is the best explanation to provide the client?
- correct answer It will promote rapid tissue healing.
A nurse is providing medication education for a client prescribed a beta-blocking agents for treatment of
glaucoma. Which statement by the client demonstrates an understanding of the mechanism of the
medication?
- correct answer It inhibits the aqueous humor production.
A nurse is planning a teaching session for a client newly prescribed a miotic drug for the treatment of
glaucoma. Which information should the nurse include in the teaching session?
- correct answer The medication enhances the aqueous humor outflow.
The healthcare provider (HCP) prescribes a medication for an older adult client who is reporting
insomnia, and the HCP instructs the client to return in two weeks. The nurse should question which
prescription?
- correct answer Eszopiclone (Lunesta) 10 milligrams orally at bedtime.
A client is diagnosed with peptic ulcer disease and receives a prescription for esomeprazole (Nexium) 20
mg capsule daily. When providing this client with discharge teaching, the nurse should include which
instruction?
- correct answer Take at same time each day one hour before eating a meal.
A client receives a new prescription for ciprofloxacin (Cipro), a synthetic quinolone. When teaching
about this drug, which information in the client's history requires special emphasis by the nurse?
- correct answer Works twenty hours a week as a lifeguard at the local pool.
