NUR 378 Pharmacology – Final Exam
2025 -Concordia University St. Paul
1. The nurse understands pharmacokinetics refers to:
A. Drug effects on the body
B. The body’s effect on the drug
C. Drug-receptor interactions
D. Genetic drug responses
Answer: B
Rationale: Pharmacokinetics = absorption, distribution, metabolism,
excretion.
2. A drug with high first-pass metabolism is expected to have:
A. High bioavailability
B. Low bioavailability
C. No hepatic influence
D. Rapid onset
Answer: B
Rationale: Liver inactivates drug before reaching circulation.
3. The main organ responsible for drug metabolism is:
A. Kidneys
B. Liver
C. Lungs
D. Intestines
Answer: B
4. The purpose of a loading dose is:
,NUR 378 Pharmacology – Final Exam
2025 -Concordia University St. Paul
A. Maintain therapeutic levels
B. Achieve therapeutic levels quickly
C. Lower toxicity
D. Improve adherence
Answer: B
5. The nurse identifies a medication error as:
A. Intentional change
B. Preventable event causing inappropriate med use
C. Normal side effect
D. Supplier issue
Answer: B
6. The traditional “Five Rights” include all EXCEPT:
A. Right drug
B. Right time
C. Right rationale
D. Right route
Answer: C
7. Hypoalbuminemia increases:
A. Bound drug
B. Free drug
,NUR 378 Pharmacology – Final Exam
2025 -Concordia University St. Paul
C. Drug excretion
D. Half-life
Answer: B
Rationale: Less protein → more active free drug.
8. A cholinergic agonist will cause:
A. Dry mouth
B. Tachycardia
C. Increased secretions
D. Pupil dilation
Answer: C
9. An anticholinergic drug causes:
A. Bradycardia
B. Urinary frequency
C. Dry mouth
D. Increased GI motility
Answer: C
10. Before giving a beta blocker, the nurse must assess:
A. Temperature
B. Heart rate
C. Pupils
D. Reflexes
, NUR 378 Pharmacology – Final Exam
2025 -Concordia University St. Paul
Answer: B
11. A major side effect of anticholinergics is:
A. Hypotension
B. Urinary retention
C. Bradycardia
D. Muscle twitching
Answer: B
12. A patient with HR 48 on metoprolol needs:
A. Next dose
B. Dose held
C. Double dose
D. Rescue inhaler
Answer: B
13. Epinephrine is used for:
A. Bradycardia
B. Hypertension
C. Anaphylaxis
D. Constipation
Answer: C
14. Bronchodilation occurs with:
2025 -Concordia University St. Paul
1. The nurse understands pharmacokinetics refers to:
A. Drug effects on the body
B. The body’s effect on the drug
C. Drug-receptor interactions
D. Genetic drug responses
Answer: B
Rationale: Pharmacokinetics = absorption, distribution, metabolism,
excretion.
2. A drug with high first-pass metabolism is expected to have:
A. High bioavailability
B. Low bioavailability
C. No hepatic influence
D. Rapid onset
Answer: B
Rationale: Liver inactivates drug before reaching circulation.
3. The main organ responsible for drug metabolism is:
A. Kidneys
B. Liver
C. Lungs
D. Intestines
Answer: B
4. The purpose of a loading dose is:
,NUR 378 Pharmacology – Final Exam
2025 -Concordia University St. Paul
A. Maintain therapeutic levels
B. Achieve therapeutic levels quickly
C. Lower toxicity
D. Improve adherence
Answer: B
5. The nurse identifies a medication error as:
A. Intentional change
B. Preventable event causing inappropriate med use
C. Normal side effect
D. Supplier issue
Answer: B
6. The traditional “Five Rights” include all EXCEPT:
A. Right drug
B. Right time
C. Right rationale
D. Right route
Answer: C
7. Hypoalbuminemia increases:
A. Bound drug
B. Free drug
,NUR 378 Pharmacology – Final Exam
2025 -Concordia University St. Paul
C. Drug excretion
D. Half-life
Answer: B
Rationale: Less protein → more active free drug.
8. A cholinergic agonist will cause:
A. Dry mouth
B. Tachycardia
C. Increased secretions
D. Pupil dilation
Answer: C
9. An anticholinergic drug causes:
A. Bradycardia
B. Urinary frequency
C. Dry mouth
D. Increased GI motility
Answer: C
10. Before giving a beta blocker, the nurse must assess:
A. Temperature
B. Heart rate
C. Pupils
D. Reflexes
, NUR 378 Pharmacology – Final Exam
2025 -Concordia University St. Paul
Answer: B
11. A major side effect of anticholinergics is:
A. Hypotension
B. Urinary retention
C. Bradycardia
D. Muscle twitching
Answer: B
12. A patient with HR 48 on metoprolol needs:
A. Next dose
B. Dose held
C. Double dose
D. Rescue inhaler
Answer: B
13. Epinephrine is used for:
A. Bradycardia
B. Hypertension
C. Anaphylaxis
D. Constipation
Answer: C
14. Bronchodilation occurs with:
