NR 507 Advanced Pathophysiology: Hypersensitivity Reactions Q&A Study Guide

NR 507 HYPERSENSITIVITY,
IMMUNODEFICIENCY, & AUTOIMMUNITY
ACTUAL QUESTIONS AND VERIFIED ANSWERS
2024 - 2025

WhichAofAtheAfollowingAisAanAautoimmuneAdisease?A-ACORRECTAANSWER-
SystemicALupusAErythematosusA(SLE).

WhatAisAaApredominantAcauseAofAsecondaryAimmuneAdeficienciesAworldwide?A-
ACORRECTAANSWER-Malnutrition



AnAexampleAofAaAsecondaryAimmunodeficiencyAis?A-ACORRECTAANSWER-
HIV,APneumocysticACarnii,APneumonia,ASinusAInfection,ALungACancer.

AnAexampleAofAaAprimaryAimmunodeficiencyAis?A-ACORRECTAANSWER-
ChronicAGranulomatousADiseaseAofAChildhood,ADiGeorgeASyndrome,AJobASyndrome,ACommonAVa
riableAImmunodificiency,AFamilialAMediterraneanAFever.

ImmunodeficienciesAareAclassifiedAasAeither:A-ACORRECTAANSWER-PrimaryAorASecondary.

PrimaryAImmunodeficiencyA-ACORRECTAANSWER-
_________AareAgeneticallyAdetermined,AwhichAmeansAthatAthereAisAaAgeneticAdefectAthatAresultsAi
nAtheAlossAofAessentialAcellsAofAtheAimmuneAsystem.

SecondaryAImmunodeficiencyA-ACORRECTAANSWER-
_________AisAcausedAbyAsomethingAexternalAtoAtheAimmuneAsystem.AForAexample,AwhenAanAindiv
idualAtakesAaAchemotherapeuticAagentAtoAtreatAcancer,AthisAcanAresultAinAimmunodeficiency

ChronicAgranulomatousADiseaseAofAChildhoodA-ACORRECTAANSWER-Primary

DiGeorgeASyndromeA-ACORRECTAANSWER-Primary

HumanAImmunodeficiencyAVirusA-ACORRECTAANSWER-Secondary

PneumocystisACariniiA-ACORRECTAANSWER-Secondary

FamilialAMediterraneanAfeverA-ACORRECTAANSWER-Primary

PneumoniaA-ACORRECTAANSWER-Secondary

, JobASyndromeA-ACORRECTAANSWER-Primary

CommonAVariableAImmunodeficiencyA-ACORRECTAANSWER-Primary

SinusAinfectionA-ACORRECTAANSWER-Secondary

LungAcancerA-ACORRECTAANSWER-Secondary

PrimaryAImmunodeficiencyA-ACORRECTAANSWER-
AreAlessAcommonAandAoccurAdueAtoAaAdefectAonAtheAdevelopmentAofAtheAimmuneAsystem.

AAsecondaryAimmuneAdisease.A-ACORRECTAANSWER-
AApatientAwithAhumanAimmunodeficiencyAvirusA(HIV)AwasAadmittedAtoAtheAacuteAcareAfacilityAwith
AdifficultyAbreathing.AHeAisAdiagnosedAwithAPneumocytisAcarinii.APneumocystisAcariniiAanAexampleA


of:

PrimaryAimmuneAdiseaseA-ACORRECTAANSWER-
AApatientAwithAChronicAGranulomatousADiseaseAofAChildhoodAhasAa

TypeA1AhypersensitivityAreaction.A-ACORRECTAANSWER-HivesA(urticaria)AareAanAexampleAofAa:

TypeA1AhypersensitivityAreaction.A-ACORRECTAANSWER-
AnaphylaxisAisAaAtypeA___AhypersensitivityAreaction.

TypeA4AhypersensitivityAreaction.A-ACORRECTAANSWER-
AllergicAcontactAdermatitisAisAanAexampleAofA

______AhypersensitivityAreaction.

NeutrophilsA-ACORRECTAANSWER-
WhichAofAtheAfollowingAareAconsideredAtheA"firstAresponders"AofAtheAinnateAimmuneAsystem?

IgGAorAIgM.A-ACORRECTAANSWER-TypeA2A(Cytotoxic)AhypersensitivityAreactionsAareAmediatedAby:

TypeAIAhypersensitivityA-ACORRECTAANSWER-reactionsAcanAbeAlocalAorAsystemic.

TypeAIAhypersensitivityAreactionA-ACORRECTAANSWER-
AllergicAasthmaAisAanAexampleAofAaA____AhypersensitivityAreaction

TypeAIAhypersensitivityAreactionA-ACORRECTAANSWER-
OnAexposureAtoAcertainAallergensA(typicallyAinhaled),AindividualsAwithAallergicAasthmaAexperienceA
inflammationAofAtheAairways,AcharacterizedAbyAtissueAswellingAandAexcessiveAmucusAproduction.A
ThisAnarrowingAofAtheAairwaysAmakesAitAdifficultAtoAbreathe.

MastAcellAdegranulationA-ACORRECTAANSWER-
WhichAofAtheAfollowingAisAtheAunderlyingApathologyAforAhayAfever?