MEDICINAL CHEMISTRY EXAM 1 WITH
ACCURATE ANSWERS AND
EXPLANATIONS
pharmacophore - ANSWER✔✔✨---the pattern of features of a molecule that is responsible for a
biological effect,
involved in drug-receptor interactions
ideal drug has... - ANSWER✔✔✨---- has a desired effect
- few side effects
- reaches intended site of action with correct concentration
- remains at the site of action for correct amt. of time
- can be removed when done
interacts with a part of the body to... - ANSWER✔✔✨---enhance or decrease an existing
physiological or biochemical process- can't make body do something its not designed to do
drug - ANSWER✔✔✨---chemical that interacts with the living org. producing an effect which can be
used to treat, diagnose, prevent a medical problem or modify a *physiological function*
therapeutic index - ANSWER✔✔✨---measure of a drug's beneficial effect at a low dose vs. harmful
effects at a high does; high index = large safety margin b/w good and toxic dose
selective toxicity - ANSWER✔✔✨---many chemicals are considered effective because they are toxic
only to 'problem' cells' and not normal cells
classification of drug molecules - ANSWER✔✔✨---pharmacological effect
ACCURATE ANSWERS AND
EXPLANATIONS
pharmacophore - ANSWER✔✔✨---the pattern of features of a molecule that is responsible for a
biological effect,
involved in drug-receptor interactions
ideal drug has... - ANSWER✔✔✨---- has a desired effect
- few side effects
- reaches intended site of action with correct concentration
- remains at the site of action for correct amt. of time
- can be removed when done
interacts with a part of the body to... - ANSWER✔✔✨---enhance or decrease an existing
physiological or biochemical process- can't make body do something its not designed to do
drug - ANSWER✔✔✨---chemical that interacts with the living org. producing an effect which can be
used to treat, diagnose, prevent a medical problem or modify a *physiological function*
therapeutic index - ANSWER✔✔✨---measure of a drug's beneficial effect at a low dose vs. harmful
effects at a high does; high index = large safety margin b/w good and toxic dose
selective toxicity - ANSWER✔✔✨---many chemicals are considered effective because they are toxic
only to 'problem' cells' and not normal cells
classification of drug molecules - ANSWER✔✔✨---pharmacological effect
