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monroe-kellie hypothesis -
correct answer ✅intracranial space made up of blood, CSF,
brain/interstitial fluid
as the pressure increases in the cranial vault, the body will
compensate by decreasing one of the other volume components
if this doesn't happen -> increased ICP
skull rigidity and brain compliance
normal ICP -
correct answer ✅<15 mmHg
how to measure ICP -
correct answer ✅subarachnoid bolt (only measures ICP, low
infection risk, can't drain CSF)
EVD (measures ICP and drains CSF but not both at the same time,
but higher infection risk)
four sites of ICP monitoring -
correct answer ✅intraventricular
subarachnoid
epidural
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parenchymal
potential complications of ICP monitoring -
correct answer ✅infections
brain damage
false readings
cerebral perfusion pressure -
correct answer ✅measures perfusion of brain tissue
MAP - ICP = CPP
normal range of 50-70
conditions that increase brain volume -
correct answer ✅space occupying masses (hematomas, abscesses,
tumors, aneurysms)
cerebral edema (brain injuries, Reye's syndrome)
conditions that increase blood volume -
correct answer ✅obstruction of venous outflow
hypercapnia (vasodilator)
PaO2 <50 (vasodilator less than effect of hypercapnia)
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conditions that increase CSF volume -
correct answer ✅increased production of CSF
decreased absorption of CSF
obstruction to flow of CSF
early signs of increased ICP -
correct answer ✅decreased LOC
HA
n/v
change in behavior
difficulty with balance
dizziness
confusion
late signs of increased ICP -
correct answer ✅pupillary dysfunction
abnormal posturing
cushing's triad