MCB 4271 FINAL QUESTIONS & ANSWERS
Antibiotic resistance occurs naturally, but the _____ of drugs in humans and animals is
accelerating the process. - Answer -underuse, use, and overuse
On average, how long does it take for the development of clinical resistance to an
antibiotic? - Answer -8 years
Factors contributing to AMR in healthcare include (choose the best answer) - Answer -
lack of antibiotics, poor sanitation, inadequate infection controls
The use of antibiotics in farm animals has been ______ in 1951. - Answer -approced
What are the reasons that make it difficult to eliminate antibiotics from their use in farm
animals? - Answer -loss of profit to animal farming companies, loss of profit to
pharmaceutical companies, easy access to antibiotics
Major host reservoirs that are exposed to antibiotic selective pressure include the
following: - Answer -Food animals, pets, and humans
What is the problem associated with the Citrus Greening Disease? - Answer -Massive
application of clinically-important antibiotics on citrus crops
Johnny developed a MRSA infections when he got injured during his baseball practice.
Johnny got a _____ acquired infection. - Answer -community
According to the WHO, antimicrobial resistance is one of the biggest threats to global
health and food security today. - Answer -True
Check all the reasons why antibiotics are used in food animals: - Answer -Growth
promotion (although banned in 2017), infection control
All strains of mold produce penicillin. True/False - Answer -False
The structure of beta-lactam antibiotics resemble: - Answer -a house
beta-lactam antibiotics are characterized by: - Answer -a 4-member ring containing a
nitrogen
penicillinases are - Answer -enzymes that deactivate penicillin
The structure below is D-ala-Dala dipeptide. What is its function? - Answer -
peptidoglycan terminus
, clavams are very potent antibiotics - Answer -false
What is this antibiotic (structure covering D-Ala-D-Ala - Answer -vancomycin
Trimethroprim binds to human DHFR - Answer -False
Inhibiting DNA synthesis arrests the cell cycle but does not kill cells. Hence,
trimethroprim is classified as a bacteriostatic antibiotic. - Answer -True
Sulfanilamide is an antibiotic. - Answer -False
Structural differences between eukaryotic and prokaryotic machinery involved in the
Central Dogma of Molecular Biology (replication, transcription, translation) allow for the
development of antibiotics that specifically target microbial cells. - Answer -True
What is this antibiotic? i cant describe this picture lol - Answer -Fluorquinolone
Quinolone antibiotics target DNA gyrase and topoisomerase IV. These type II
topoisomerases are also found within the human proteome. - Answer -False
Which of the following statements is true about rifampin? - Answer -It inhibits bacterial
RNA polymerase.
What is the function of sulfanilamide? - Answer -inhibits dihydropteroate synthase
The antibiotic structure show below is (4 six-membered rings) - Answer -a tetracycline
Tetracyclines bind to the 50S ribosomal subunit. - Answer -False
Chloramphenicol binds to 50S ribosomal subunit and inhibits peptidyl transferase -
Answer -True
What is the function of the hydrophobic fatty acid chain in lipopeptides? - Answer -
Allows the antibiotic to penetrate cell membrane
The majority of antibiotic classes were developed during the Golden Age of antibiotics.
Since then, very few new classes were introduced into clinical use. - Answer -True
Hemoperfusion devices - Answer -Filtering blood from bacteria
Quorum sensing inhibitors - Answer -Disruption of bacteria-to-bacteria communication
Lytic bacteriophages - Answer -Virus-mediated selective killing of bacteria
Vaccines - Answer -Stimulation of the immune system
Antibiotic resistance occurs naturally, but the _____ of drugs in humans and animals is
accelerating the process. - Answer -underuse, use, and overuse
On average, how long does it take for the development of clinical resistance to an
antibiotic? - Answer -8 years
Factors contributing to AMR in healthcare include (choose the best answer) - Answer -
lack of antibiotics, poor sanitation, inadequate infection controls
The use of antibiotics in farm animals has been ______ in 1951. - Answer -approced
What are the reasons that make it difficult to eliminate antibiotics from their use in farm
animals? - Answer -loss of profit to animal farming companies, loss of profit to
pharmaceutical companies, easy access to antibiotics
Major host reservoirs that are exposed to antibiotic selective pressure include the
following: - Answer -Food animals, pets, and humans
What is the problem associated with the Citrus Greening Disease? - Answer -Massive
application of clinically-important antibiotics on citrus crops
Johnny developed a MRSA infections when he got injured during his baseball practice.
Johnny got a _____ acquired infection. - Answer -community
According to the WHO, antimicrobial resistance is one of the biggest threats to global
health and food security today. - Answer -True
Check all the reasons why antibiotics are used in food animals: - Answer -Growth
promotion (although banned in 2017), infection control
All strains of mold produce penicillin. True/False - Answer -False
The structure of beta-lactam antibiotics resemble: - Answer -a house
beta-lactam antibiotics are characterized by: - Answer -a 4-member ring containing a
nitrogen
penicillinases are - Answer -enzymes that deactivate penicillin
The structure below is D-ala-Dala dipeptide. What is its function? - Answer -
peptidoglycan terminus
, clavams are very potent antibiotics - Answer -false
What is this antibiotic (structure covering D-Ala-D-Ala - Answer -vancomycin
Trimethroprim binds to human DHFR - Answer -False
Inhibiting DNA synthesis arrests the cell cycle but does not kill cells. Hence,
trimethroprim is classified as a bacteriostatic antibiotic. - Answer -True
Sulfanilamide is an antibiotic. - Answer -False
Structural differences between eukaryotic and prokaryotic machinery involved in the
Central Dogma of Molecular Biology (replication, transcription, translation) allow for the
development of antibiotics that specifically target microbial cells. - Answer -True
What is this antibiotic? i cant describe this picture lol - Answer -Fluorquinolone
Quinolone antibiotics target DNA gyrase and topoisomerase IV. These type II
topoisomerases are also found within the human proteome. - Answer -False
Which of the following statements is true about rifampin? - Answer -It inhibits bacterial
RNA polymerase.
What is the function of sulfanilamide? - Answer -inhibits dihydropteroate synthase
The antibiotic structure show below is (4 six-membered rings) - Answer -a tetracycline
Tetracyclines bind to the 50S ribosomal subunit. - Answer -False
Chloramphenicol binds to 50S ribosomal subunit and inhibits peptidyl transferase -
Answer -True
What is the function of the hydrophobic fatty acid chain in lipopeptides? - Answer -
Allows the antibiotic to penetrate cell membrane
The majority of antibiotic classes were developed during the Golden Age of antibiotics.
Since then, very few new classes were introduced into clinical use. - Answer -True
Hemoperfusion devices - Answer -Filtering blood from bacteria
Quorum sensing inhibitors - Answer -Disruption of bacteria-to-bacteria communication
Lytic bacteriophages - Answer -Virus-mediated selective killing of bacteria
Vaccines - Answer -Stimulation of the immune system
