lOMoARcPSD|17706574
NR283 PATHO EDAPT WK2
INFLAMMATION
What are the signs of acute inflammation?
PAIN
HEAT
REDNESS
SWELLING
(PRISH: Pain, Redness, Immobility, Swelling, Heat)
Which immune chemical mediators contribute to the swelling associated with acute
inflammation?
Histamine
Leukotrienes
Prostaglandins
Kinins
Which item causes chronic inflammation?
A: Foreign material that remains in the body
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, lOMoARcPSD|17706574
Characteristics of Acute Versus Chronic Inflammation
Acute Inflammation Chronic Inflammation
Pathogens Persistent acute inflammation
Cause Allergies Persistent foreign body
Injury Autoimmune reaction
Delayed/Up to months or
Onset/Duration Immediate/Several days
years
Complement system
Kinins
Primary Chemical
Cytokinin’s
Mediators Leukotrienes
Interferon-gamma
Monocytes
Infection: neutrophils, monocytes,
Macrophages
Primary Immune macrophages
Cells Lymphocytes
Allergy: eosinophils, mast cells
Fibroblasts
Rash Rash
Lesion Pus Fibrosis
Abscess Granuloma
Resolution
Tissue destruction
Outcomes Abscess formation
Fibrosis
Chronic inflammation
Autoimmune disorders
Abscess (skin, organ)
(rheumatoid arthritis)
Examples
Allergic reaction (anaphylaxis)
Cystic fibrosis
Healing by _______ intention occurs when a wound is clean, free of foreign material,
and the edges are held close together.
A: Primary
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, lOMoARcPSD|17706574
A client is seen in the emergency clinic after jumping off a ski lift and injuring their
ankle. Which steps can the client take to reduce inflammation and pain? Select all
that apply.
Wrap the ankle
Rest the affected area
Apply an ice pack
Elevate the injured site
R-I-C-E is the correct option.
Rest the affected area, which will protect the area from additional injury.
Ice the ankle to reduce inflammation that is causing swelling or pain. Applying heat
will not reduce inflammation and swelling.
Compression by wrapping the ankle can reduce the swelling.
Elevate the ankle to reduce swelling.
Which factor can delay tissue healing from inflammation and injury?
A: Advanced age
Can delay tissue healing from inflammation and injury due to reduced mitosis.
Scar tissue is _____ and tends to ______ over time, which can result in _________
Nonelastic
Shrink
Complications
A 72-year-old is recovering two days after having knee replacement surgery. The
incision is going through which type of healing?
A: Primary intention
A client who has been experiencing stomach pains for the past three months visits the
healthcare provider to receive the results of their diagnostic test. The client is
informed the test revealed an ulcer with fibrosis, fibroblasts, and macrophages
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, lOMoARcPSD|17706574
present. The client's treatment plan should address the ______ inflammation
pathologic process.
A: Chronic
On post-op day one following abdominal surgery, a client is experiencing pain, heat,
and redness at the incision. Based on these findings, what conclusion can be made
about the incision?
A: This is a normal inflammatory response.
Which characteristics below are expected during an acute or chronic
inflammatory episode?
Acute Chronic
Inflammation Inflammation
The immediate response to
tissue injury, which lasts
from minutes to days. x
The repeated destruction and
repair of tissue for weeks to
years after the initial injury. x
Used to describe diseases
characterized by long
duration and slow x
progression.
Used to describe diseases
characterized by sudden onset
with a short, relatively severe x
Downloaded by Nicholas Marks ()
NR283 PATHO EDAPT WK2
INFLAMMATION
What are the signs of acute inflammation?
PAIN
HEAT
REDNESS
SWELLING
(PRISH: Pain, Redness, Immobility, Swelling, Heat)
Which immune chemical mediators contribute to the swelling associated with acute
inflammation?
Histamine
Leukotrienes
Prostaglandins
Kinins
Which item causes chronic inflammation?
A: Foreign material that remains in the body
Downloaded by Nicholas Marks ()
, lOMoARcPSD|17706574
Characteristics of Acute Versus Chronic Inflammation
Acute Inflammation Chronic Inflammation
Pathogens Persistent acute inflammation
Cause Allergies Persistent foreign body
Injury Autoimmune reaction
Delayed/Up to months or
Onset/Duration Immediate/Several days
years
Complement system
Kinins
Primary Chemical
Cytokinin’s
Mediators Leukotrienes
Interferon-gamma
Monocytes
Infection: neutrophils, monocytes,
Macrophages
Primary Immune macrophages
Cells Lymphocytes
Allergy: eosinophils, mast cells
Fibroblasts
Rash Rash
Lesion Pus Fibrosis
Abscess Granuloma
Resolution
Tissue destruction
Outcomes Abscess formation
Fibrosis
Chronic inflammation
Autoimmune disorders
Abscess (skin, organ)
(rheumatoid arthritis)
Examples
Allergic reaction (anaphylaxis)
Cystic fibrosis
Healing by _______ intention occurs when a wound is clean, free of foreign material,
and the edges are held close together.
A: Primary
Downloaded by Nicholas Marks ()
, lOMoARcPSD|17706574
A client is seen in the emergency clinic after jumping off a ski lift and injuring their
ankle. Which steps can the client take to reduce inflammation and pain? Select all
that apply.
Wrap the ankle
Rest the affected area
Apply an ice pack
Elevate the injured site
R-I-C-E is the correct option.
Rest the affected area, which will protect the area from additional injury.
Ice the ankle to reduce inflammation that is causing swelling or pain. Applying heat
will not reduce inflammation and swelling.
Compression by wrapping the ankle can reduce the swelling.
Elevate the ankle to reduce swelling.
Which factor can delay tissue healing from inflammation and injury?
A: Advanced age
Can delay tissue healing from inflammation and injury due to reduced mitosis.
Scar tissue is _____ and tends to ______ over time, which can result in _________
Nonelastic
Shrink
Complications
A 72-year-old is recovering two days after having knee replacement surgery. The
incision is going through which type of healing?
A: Primary intention
A client who has been experiencing stomach pains for the past three months visits the
healthcare provider to receive the results of their diagnostic test. The client is
informed the test revealed an ulcer with fibrosis, fibroblasts, and macrophages
Downloaded by Nicholas Marks ()
, lOMoARcPSD|17706574
present. The client's treatment plan should address the ______ inflammation
pathologic process.
A: Chronic
On post-op day one following abdominal surgery, a client is experiencing pain, heat,
and redness at the incision. Based on these findings, what conclusion can be made
about the incision?
A: This is a normal inflammatory response.
Which characteristics below are expected during an acute or chronic
inflammatory episode?
Acute Chronic
Inflammation Inflammation
The immediate response to
tissue injury, which lasts
from minutes to days. x
The repeated destruction and
repair of tissue for weeks to
years after the initial injury. x
Used to describe diseases
characterized by long
duration and slow x
progression.
Used to describe diseases
characterized by sudden onset
with a short, relatively severe x
Downloaded by Nicholas Marks ()
