TEST BANK For Psychopharmacology Drugs the Brain and Behavior 4th Edition By Meyer Nursing, Verified Chapters 1 - 20

Chapter 1. Principles of Pharmacology
TEST BANK For Psychopharmacology Chapter 2. Structure and Function of the Nervous System
Chapter 3. Chemical Signaling by Neurotransmitters and Hormones
Drugs the Brain and Behavior 4th Edition Chapter 4. Methods of Research in Psychopharmacology
Chapter 5. Catecholamines
By Meyer Nursing, Verified Chapters 1 - 20 Chapter 6. Serotonin
Chapter 7. Acetylcholine
Chapter 8. Glutamate and GABA
Chapter 9. Drug Abuse and Addiction
Chapter 10. Alcohol
Chapter 11. The Opioids
Chapter 12. Psychomotor Stimulants: Cocaine, Amphetamine, and Related Drugs
Chapter 13. Nicotine and Caffeine
Chapter 14. Marijuana and the Cannabinoids
Chapter 15. Hallucinogens, PCP, and Ketamine
Chapter 16. Inhalants, GHB, and Anabolic-Androgenic Steroids
Chapter 17. Disorders of Anxiety and Impulsivity and the Drugs Used to Treat These
Disorders
Chapter 18. Affective Disorders: Antidepressants and Mood Stabilizers
Chapter 19. Schizophrenia: Antipsychotic Drugs
Chapter 20. Neurodegenerative Diseases




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, ANSWER: b
Textbook Reference: Pharmacology: The Science of Drug Action
Chapter 1: Principles of Pharmacology
4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
Multiple Choice b. Genetic variation
c. Drug competition
1. refer(s) to specific molecular changes that occur when a drug binds to a d. Expectation of outcome
particular target site or receptor, while are the resulting widespread alterations ANSWER: c
in function. Textbook Reference: Pharmacology: The Science of Drug Action
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
ANSWER: d
Textbook Reference: Pharmacology: The Science of Drug Action


2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
ANSWER: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action


3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.

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,5. The administration eof eoxytocin ehas ebeen eproposed eas ea etreatment efor
eautism. 9. First-pass emetabolism eoccurs ewith eorally eadministered edrugs ebecause

a. intravenous a. their eabsorption eis eslowed eby efood.

b. oral b. drugs eabsorbed einto ethe ebloodstream efrom ethe estomach ego eto ethe eliver eon ethe

c. intranasal eway etoegeneral ecirculation.


d. intracerebral c. drugs emust efirst esurvive ethe eacidic eenvironment eof ethe estomach.

ANSWER: ec d. salivary eenzymes ein ethe emouth ebegin ethe eprocess eof emetabolism.

Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction ANSWER: eb
Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction

6. Which efactor edoes enot eaffect ethe epharmacokinetics eof ea edrug?
a. Route eof eadministration 10. Toxic esubstances ein ethe eblood etrigger ea evomiting eresponse eby eactivating ethe

b. Lipid esolubility a. blood–brain ebarrier.

c. Depot ebinding b. choroid eplexus.

d. Drug eaction c. area epostrema.

ANSWER: ed d. median eeminence.

Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction


7. First-pass emetabolism eoccurs ewhen edrugs eare etaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
ANSWER: ea
Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction


8. The earea epostrema eis eone earea ein ethe ebrain ewhere ethe is enot ecomplete.
a. cerebrospinal efluid
b. blood–brain ebarrier
c. choroid eplexus
d. phospholipid emembrane
ANSWER: eb
Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction

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, ANSWER: ec d. highly elipid-soluble

Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction ANSWER: ea
Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction

11. Drugs eadministered e_ have ethe emost erapid eonset eof eaction.
a. subcutaneously 15. Agents ethat einduce edevelopmental eabnormalities ein ea efetus eare eknown eas

b. intramuscularly a. psychoactive edrugs.

c. orally b. illicit edrugs.

d. intravenously c. teratogens.

ANSWER: ed d. placental edrugs.

Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction ANSWER: ec
Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction

12. Ionization eof ea edrug edepends eon ethe of ethe esolution eand ethe of
etheedrug. 16. Depot ebinding eis esaid eto eoccur ewhen edrugs

a. pH; epKa a. bind eto etheir etarget esites.

b. pKa; epH
c. concentration; elipid esolubility
d. pH; econcentration
ANSWER: ea
Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction


13. The eabsorption eof ea edrug edepends eon eall eof ethe efollowing eexcept
a. lipid esolubility.
b. ionization.
c. body etemperature.
d. the econcentration eof ethe edrug.
ANSWER: ec
Textbook eReference: ePharmacokinetic eFactors eDetermining eDrug eAction


14. Drugs ethat eare should ebe eavoided eby ewomen eof echildbearing eage.
a. teratogenic
b. able eto ecross ethe eplacental ebarrier
c. psychoactive

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