CPIA UPDATED QUESTIONS AND ANSWERS GUARANTEE
A+
✔✔Which of the following statements is true about the use of carbon monoxide for
euthanasia?
a) Acceptable for individual or mass euthanasia of cattle, horses, and other large
mammals.
b) It is extremely stressful to the animal.
c) Death occurs rapidly at concentrations of 4 to 6%.
d) This agent is safe to use by human operators. - ✔✔c) Death occurs rapidly at
concentrations of 4 to 6%.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Confirmation of death is determined by:
a) Lack of movement
b) Duration of euthanasia procedure
c) Cessation of vital signs
d) Use of an adjunctive euthanasia method - ✔✔c) Cessation of vital signs
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔What is the mode of euthanasia action for an overdose of barbiturates?
a) Depresses the CNS leading to cardiac arrest
b) Over stimulates the CNS causing cardiac arrhythmia
c) Causes hypoxia and brain activity ceases
d) Paralyzes lungs and breathing ceases - ✔✔a) Depresses the CNS leading to cardiac
arrest
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following is a definition of euthanasia as described in the AVMA
Guidelines?
a) The act of killing animals by methods that preserve physiologic function after death
,b) The act of killing animals by methods that induce rapid unconsciousness and death
with minimal pain or distress
c) The act of reducing the emotional state of animals under distress
d) The act of preparing animals for a surgical or otherwise invasive procedure - ✔✔b)
The act of killing animals by methods that induce rapid unconsciousness and death with
minimal pain or distress
Feedback: Euthanasia as defined by the Animal Welfare Act (AWA): ""The humane
destruction of an animal must be accomplished by a method that produces rapid
unconsciousness and subsequent death without evidence of pain or distress, or a
method that utilizes anesthesia produced by an agent that causes painless loss of
consciousness and subsequent death.""
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Euthanasia agents that act by way of hypoxia are not recommended for which of the
following groups of animals?
a) Warm-blooded neonates
b) Ruminants
c) Older animals of most species
d) Animals with respiratory problems - ✔✔a) Warm-blooded neonates
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following statements is true about inhalant agents used for euthanasia?
a) Since inhalant anesthetic effects are specific to the animal species being euthanized,
no special precautions for personnel are required.
b) Due to their small size, inhalants provide a quick euthanasia method for neonatal
animals.
c) Using a low concentration of inhalation agent is the preferred method to conduct
euthanasia procedures.
d) Animals should be protected from contact with the liquid form of the anesthetic agent.
- ✔✔d) Animals should be protected from contact with the liquid form of the anesthetic
agent.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following statements is true when using CO2 for euthanasia?
,a) It is best to combine carbon dioxide with oxygen for euthanasia.
b) Pulmonary lesions may occur if the carbon dioxide concentration reaches 40%.
c) The optimal flow rate is one that displaces 10% of the chamber volume every minute.
d) Gas flow should be maintained for at least 1 minute after apparent death to make
sure the animal does not recover. - ✔✔d) Gas flow should be maintained for at least 1
minute after apparent death to make sure the animal does not recover.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Immersing aquatic species in a bath saturated with carbon dioxide is an acceptable
euthanasia method.
a) True
b) False - ✔✔a) True
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following statements concerning euthanasia is incorrect?
a) Physical methods of euthanasia are most desirable when used on conscious
animals.
b) When used alone, non-physical methods of euthanasia are usually preferred over
physical methods.
c) Physical methods of euthanasia are most desirable when used on anesthetized
animals.
d) The investigator must provide a scientific justification to the IACUC if a physical
method will be used alone. - ✔✔a) Physical methods of euthanasia are most desirable
when used on conscious animals.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Chloral hydrate is conditionally acceptable for use in large animals that:
a) are already sedated.
b) cannot be easily restrained.
c) will have an adjunctive method of euthanasia following the injection of chloral
hydrate.
d) None of the above - ✔✔a) are already sedated.
, Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following mandates require the provision of occupational health
services for employees who work in animal facilities?
a) Occupational Health and Safety Act
b) GLPS
c) Animal Welfare Act
d) PHS Policy - ✔✔d) PHS Policy
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines >
Occupational Health and Safety in the Care and Use of Research Animals"
✔✔Serum collection and storage may be of value in which of the following situations?
a) A veterinary technician is providing medical care to rabbits in safety assessment
studies.
b) Employees have a substantial possibility of acquiring an infection that can be
detected serologically.
c) A research technician is caring for genetically altered mice used in basic research.
d) Janitorial staff is involved in cleaning operating room suites. - ✔✔b) Employees have
a substantial possibility of acquiring an infection that can be detected serologically.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines >
Occupational Health and Safety in the Care and Use of Research Animals"
✔✔Which person is primarily responsible for developing and sustaining a useful
occupational health and safety program?
a) IACUC chairperson
b) Senior institutional official
c) Attending veterinarian
d) Vivarium manager - ✔✔b) Senior institutional official
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines >
Occupational Health and Safety in the Care and Use of Research Animal"
✔✔Which of the following statements is false concerning shigellosis?
A+
✔✔Which of the following statements is true about the use of carbon monoxide for
euthanasia?
a) Acceptable for individual or mass euthanasia of cattle, horses, and other large
mammals.
b) It is extremely stressful to the animal.
c) Death occurs rapidly at concentrations of 4 to 6%.
d) This agent is safe to use by human operators. - ✔✔c) Death occurs rapidly at
concentrations of 4 to 6%.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Confirmation of death is determined by:
a) Lack of movement
b) Duration of euthanasia procedure
c) Cessation of vital signs
d) Use of an adjunctive euthanasia method - ✔✔c) Cessation of vital signs
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔What is the mode of euthanasia action for an overdose of barbiturates?
a) Depresses the CNS leading to cardiac arrest
b) Over stimulates the CNS causing cardiac arrhythmia
c) Causes hypoxia and brain activity ceases
d) Paralyzes lungs and breathing ceases - ✔✔a) Depresses the CNS leading to cardiac
arrest
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following is a definition of euthanasia as described in the AVMA
Guidelines?
a) The act of killing animals by methods that preserve physiologic function after death
,b) The act of killing animals by methods that induce rapid unconsciousness and death
with minimal pain or distress
c) The act of reducing the emotional state of animals under distress
d) The act of preparing animals for a surgical or otherwise invasive procedure - ✔✔b)
The act of killing animals by methods that induce rapid unconsciousness and death with
minimal pain or distress
Feedback: Euthanasia as defined by the Animal Welfare Act (AWA): ""The humane
destruction of an animal must be accomplished by a method that produces rapid
unconsciousness and subsequent death without evidence of pain or distress, or a
method that utilizes anesthesia produced by an agent that causes painless loss of
consciousness and subsequent death.""
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Euthanasia agents that act by way of hypoxia are not recommended for which of the
following groups of animals?
a) Warm-blooded neonates
b) Ruminants
c) Older animals of most species
d) Animals with respiratory problems - ✔✔a) Warm-blooded neonates
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following statements is true about inhalant agents used for euthanasia?
a) Since inhalant anesthetic effects are specific to the animal species being euthanized,
no special precautions for personnel are required.
b) Due to their small size, inhalants provide a quick euthanasia method for neonatal
animals.
c) Using a low concentration of inhalation agent is the preferred method to conduct
euthanasia procedures.
d) Animals should be protected from contact with the liquid form of the anesthetic agent.
- ✔✔d) Animals should be protected from contact with the liquid form of the anesthetic
agent.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following statements is true when using CO2 for euthanasia?
,a) It is best to combine carbon dioxide with oxygen for euthanasia.
b) Pulmonary lesions may occur if the carbon dioxide concentration reaches 40%.
c) The optimal flow rate is one that displaces 10% of the chamber volume every minute.
d) Gas flow should be maintained for at least 1 minute after apparent death to make
sure the animal does not recover. - ✔✔d) Gas flow should be maintained for at least 1
minute after apparent death to make sure the animal does not recover.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Immersing aquatic species in a bath saturated with carbon dioxide is an acceptable
euthanasia method.
a) True
b) False - ✔✔a) True
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following statements concerning euthanasia is incorrect?
a) Physical methods of euthanasia are most desirable when used on conscious
animals.
b) When used alone, non-physical methods of euthanasia are usually preferred over
physical methods.
c) Physical methods of euthanasia are most desirable when used on anesthetized
animals.
d) The investigator must provide a scientific justification to the IACUC if a physical
method will be used alone. - ✔✔a) Physical methods of euthanasia are most desirable
when used on conscious animals.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines
✔✔Chloral hydrate is conditionally acceptable for use in large animals that:
a) are already sedated.
b) cannot be easily restrained.
c) will have an adjunctive method of euthanasia following the injection of chloral
hydrate.
d) None of the above - ✔✔a) are already sedated.
, Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia
of Research Animals: AVMA Guidelines"
✔✔Which of the following mandates require the provision of occupational health
services for employees who work in animal facilities?
a) Occupational Health and Safety Act
b) GLPS
c) Animal Welfare Act
d) PHS Policy - ✔✔d) PHS Policy
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines >
Occupational Health and Safety in the Care and Use of Research Animals"
✔✔Serum collection and storage may be of value in which of the following situations?
a) A veterinary technician is providing medical care to rabbits in safety assessment
studies.
b) Employees have a substantial possibility of acquiring an infection that can be
detected serologically.
c) A research technician is caring for genetically altered mice used in basic research.
d) Janitorial staff is involved in cleaning operating room suites. - ✔✔b) Employees have
a substantial possibility of acquiring an infection that can be detected serologically.
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines >
Occupational Health and Safety in the Care and Use of Research Animals"
✔✔Which person is primarily responsible for developing and sustaining a useful
occupational health and safety program?
a) IACUC chairperson
b) Senior institutional official
c) Attending veterinarian
d) Vivarium manager - ✔✔b) Senior institutional official
Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines >
Occupational Health and Safety in the Care and Use of Research Animal"
✔✔Which of the following statements is false concerning shigellosis?
