NR565 Advanced Pharmacology Midterm
Save
Students also studied
Alpha adrenergic drugs: PConn3 Top Meds Week 5 (Brand & ... Chapter 7 Endocrine System Pharm
11 terms 50 terms 39 terms 25 terms
halaalzaqzuqq Preview hannahhdoan Preview annkos152 Preview PUP
What schedule drugs can APRNs It depends on the governing body in each state. In AZ there are no restrictions on
prescribe? APRN prescribing by schedule.
Who determines and regulates prescriptive AZ - State Board of Nursing
authority?
How does limited prescriptive authority Creates numerous barriers to quality affordable and acessible patient care.
impact patients within the healthcare
system?
1. Be prudent and deliberate in your decision-making process
2. Have a documented provider-patient relationship with the person for whom you
are prescribing
What are the key responsibilities of 3. Do not prescribe medications for family or friends or for yourself
prescribing? 4. Document a thorough history and physical examination in your records
5.Include any discussions you have with the patient regarding risk factors, side
effects, or therapy options
6. Have a documented plan regarding drug monitoring or titration, if applicable.
Cost, availability, current practice guidelines, medication interactions with food side
What should be used to make prescribing
effects need for monitoring how drug is metabolized. special populations. ask if
decisions?
prescriptions are cost prohibitive.
Be familiar with pharmacokinetic and Older adults often metabolize drugs more slowly. Dosages may need to be adjusted
pharmacodynamic changes of older adults to accommodate age related changes in GI system, liver function, kidney function,
and how that would translate to baseline etc.
information needed to prescribe.
What is the BEERS criteria? lists potentially inappropriate drugs that lead to adverse effects in the elderly
It provides a list of medications that are potentially harmful in elderly. List that
identifies drugs with a high likelihood of causing adverse effects in older adults.
Beers Criteria are recommendations; ultimately prescribers must determine whether
why is the BEERS criteria important?
a medication is appropriate for use or not. These guidelines are not intended to limit
the use of medications or apply to all older adults. Safe and judicious prescribing is
crucial in the older adult to optimize pharmacotherapy.
Impacts/outcomes of polypharmacy - drug interactions with mild side effects to life-threatening consequences
CYP450 inhibitors inhibit metabolism, increase blood levels of medications
, CRACK AMIGOS
Cimetidine
Ritonavir
Amiodarone
Ciprofloxacin
CYP450 inhibitors mnemonic ^ drug levels Ketoconazole
Acute Alcohol Use
Macrolides
Isoniazid
Grapefruit Juice
Omeprazole
Sulfonamides
Bull Shit CRAP GPS induces my rage.
Barbiturates
St. John's wort
Carbamzapine
CYP450 inducers mnemonic Rifampin
Alcohol (Chronic use)
Phenytoin
Griseofulvin
Phenobarbital
Sulfonylureas
increase rate of metabolism breaking down more drug. Subsequently reducing the
CYP450 inducers
therapeutic concentration of the drug.
What happens when someone has a poor medications metabolized slower, medication might not work or put them at risk for
metabolism phenotype? side-effects
What does the US food and drug Whether the drug is safe, effective, and benefits of a drug outweigh the risks
administration regulate when it comes to
medications?
reasons for medication non-adherence forgetfulness, lack of planning, cost, dissatisfaction, altered dosing
A type of warning that appears in a drug's prescribing information and is required by
black box warning the U.S. Food and Drug Administration (FDA) to alert prescribers of serious adverse
events that have occurred with the given drug.
Neonate and infant drug absorption Drug absorption is different up to 2 years of age and is affected by the maturation
Be familiar with general development and process of various organs.
when absorption would reach adult levels
Lack of education - many health care providers do not possess the knowledge or
comfort to interpret the results
Common fears with genetic testing
financial cost - many insurance plans do not cover this. cost can be from $100-2000.
discrimination from employers, insurance companies or providers
Guiding principles for prescribers for CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States,
Opioids 2022
Morphine (strong or moderate-strong)
Examples of pure opioid agonists
Codeine (moderate-strong)
What is used to calculate a patients Calculate morphine milligram equivalent
overdose risk?
Save
Students also studied
Alpha adrenergic drugs: PConn3 Top Meds Week 5 (Brand & ... Chapter 7 Endocrine System Pharm
11 terms 50 terms 39 terms 25 terms
halaalzaqzuqq Preview hannahhdoan Preview annkos152 Preview PUP
What schedule drugs can APRNs It depends on the governing body in each state. In AZ there are no restrictions on
prescribe? APRN prescribing by schedule.
Who determines and regulates prescriptive AZ - State Board of Nursing
authority?
How does limited prescriptive authority Creates numerous barriers to quality affordable and acessible patient care.
impact patients within the healthcare
system?
1. Be prudent and deliberate in your decision-making process
2. Have a documented provider-patient relationship with the person for whom you
are prescribing
What are the key responsibilities of 3. Do not prescribe medications for family or friends or for yourself
prescribing? 4. Document a thorough history and physical examination in your records
5.Include any discussions you have with the patient regarding risk factors, side
effects, or therapy options
6. Have a documented plan regarding drug monitoring or titration, if applicable.
Cost, availability, current practice guidelines, medication interactions with food side
What should be used to make prescribing
effects need for monitoring how drug is metabolized. special populations. ask if
decisions?
prescriptions are cost prohibitive.
Be familiar with pharmacokinetic and Older adults often metabolize drugs more slowly. Dosages may need to be adjusted
pharmacodynamic changes of older adults to accommodate age related changes in GI system, liver function, kidney function,
and how that would translate to baseline etc.
information needed to prescribe.
What is the BEERS criteria? lists potentially inappropriate drugs that lead to adverse effects in the elderly
It provides a list of medications that are potentially harmful in elderly. List that
identifies drugs with a high likelihood of causing adverse effects in older adults.
Beers Criteria are recommendations; ultimately prescribers must determine whether
why is the BEERS criteria important?
a medication is appropriate for use or not. These guidelines are not intended to limit
the use of medications or apply to all older adults. Safe and judicious prescribing is
crucial in the older adult to optimize pharmacotherapy.
Impacts/outcomes of polypharmacy - drug interactions with mild side effects to life-threatening consequences
CYP450 inhibitors inhibit metabolism, increase blood levels of medications
, CRACK AMIGOS
Cimetidine
Ritonavir
Amiodarone
Ciprofloxacin
CYP450 inhibitors mnemonic ^ drug levels Ketoconazole
Acute Alcohol Use
Macrolides
Isoniazid
Grapefruit Juice
Omeprazole
Sulfonamides
Bull Shit CRAP GPS induces my rage.
Barbiturates
St. John's wort
Carbamzapine
CYP450 inducers mnemonic Rifampin
Alcohol (Chronic use)
Phenytoin
Griseofulvin
Phenobarbital
Sulfonylureas
increase rate of metabolism breaking down more drug. Subsequently reducing the
CYP450 inducers
therapeutic concentration of the drug.
What happens when someone has a poor medications metabolized slower, medication might not work or put them at risk for
metabolism phenotype? side-effects
What does the US food and drug Whether the drug is safe, effective, and benefits of a drug outweigh the risks
administration regulate when it comes to
medications?
reasons for medication non-adherence forgetfulness, lack of planning, cost, dissatisfaction, altered dosing
A type of warning that appears in a drug's prescribing information and is required by
black box warning the U.S. Food and Drug Administration (FDA) to alert prescribers of serious adverse
events that have occurred with the given drug.
Neonate and infant drug absorption Drug absorption is different up to 2 years of age and is affected by the maturation
Be familiar with general development and process of various organs.
when absorption would reach adult levels
Lack of education - many health care providers do not possess the knowledge or
comfort to interpret the results
Common fears with genetic testing
financial cost - many insurance plans do not cover this. cost can be from $100-2000.
discrimination from employers, insurance companies or providers
Guiding principles for prescribers for CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States,
Opioids 2022
Morphine (strong or moderate-strong)
Examples of pure opioid agonists
Codeine (moderate-strong)
What is used to calculate a patients Calculate morphine milligram equivalent
overdose risk?
