Reproductive-FA exam

Reproductive-FA exam




2. 636


Embryology


genes involoved in embryogenesis 4: Sonic hedgehog (SHH) gene


Wnt-7 gene
Fibroblast growth factor (FGF) gene
Homeobox (Hox) genes

3. site and function of the genes 4


SHH


-site


-action 2


-mutation


,Wnt 7 gene


-site


-action


FGF gene


-site


-action


hox gene


-site


-action


-mutation result


eg: Sonic hedgehog (SHH) gene




,-base of limbs
-ant/pos axis,CNS dev
-holoprosencephaly


Wnt-7 gene
-distal end of limbs






, -dorsal/ventral axis


Fibroblast growth factor (FGF) gene
-apical ectodermal ridge
-limb lengthening


Homeobox (Hox) genes
-multiple
-craniocaudal segmental development
-appendages in wrong sites
-isotretinoine>increase hox gene expression

4. embryogenesis


-week 1-secretes,result


-week 2,layers


-week 3,layers,



mesoderm formed how,through


how is neural plate formed