P
PRRE
EMM II U
UMM SS TT U
UDDY
Y M
MAA TT E
ERR II A
A LL SS STUDY COLLECTION: 2025
PATHO 370 - IN CLASS QUIZ 2 (CH. 10, 11, 13, 14, 15)
EXAM QUESTIONS AND CORRECT ANSWERS
WHAT'S INSIDE:
Latest 2025/2026 Questions
Verified Correct Answers Highlighted for Easy Learning
Detailed Explanations & Rationales for Better Understanding
Proven to Boost Grades and Exam Confidence
Covers All Essential Topics and Core Concepts
Perfect for Quick Revision and Last-Minute Review
Question 1
Which laboratory finding confirms iron‑deficiency anemia?
A. Elevated serum ferritin
B. Decreased total iron‑binding capacity
C. Elevated total iron‑binding capacity
D. Increased mean corpuscular hemoglobin concentration
Correct Answer
Elevated total iron‑binding capacity
Rationale:
TIBC rises when iron stores are depleted, indicating iron deficiency.
,Question 2
A newborn with hemophilia B lacks functional factor IX.
A. Factor VIII
B. Factor IX
C. Factor XI
D. Factor XII
Correct Answer
Factor IX
Rationale:
Hemophilia B is caused by deficiency of clotting factor IX.
Question 3
The Philadelphia chromosome creates the BCR‑ABL fusion gene.
A. c‑myc
B. BCR‑ABL
C. JAK2
D. PML‑RARα
Correct Answer
BCR‑ABL
Rationale:
t(9;22) translocation fuses BCR and ABL, driving chronic myeloid leukemia.
Question 4
Which vitamin deficiency causes macrocytic, megaloblastic anemia?
A. Vitamin B12
B. Vitamin C
C. Vitamin D
D. Vitamin K
Correct Answer
Vitamin B12
Rationale:
B12 deficiency impairs DNA synthesis, producing large, immature red cells.
,Question 5
Erythropoietin therapy is most effective for anemia of chronic kidney disease.
A. Iron supplements
B. Erythropoietin administration
C. Folic acid
D. Vitamin B12 injections
Correct Answer
Erythropoietin administration
Rationale:
Kidney failure reduces endogenous erythropoietin, requiring exogenous replacement.
Question 6
The most serious complication of intensive chemotherapy is infection.
A. Mucositis
B. Neurotoxicity
C. Infection
D. Hair loss
Correct Answer
Infection
Rationale:
Myelosuppression predisposes patients to severe bacterial and fungal infections.
Question 7
Type IV hypersensitivity reactions are mediated by T‑cell–dependent mechanisms.
A. Type I
B. Type II
C. Type III
D. Type IV
Correct Answer
Type IV
Rationale:
Delayed‑type hypersensitivity involves sensitized T‑cells without antibody involvement.
, Question 8
Which lab values are decreased in iron‑deficiency anemia? (Select all that apply)
A. MCV
B. MCH
C. MCHC
D. RDW
Correct Answer
MCV
Rationale:
Iron deficiency reduces hemoglobin content, lowering mean corpuscular volume.
Question 9
Systemic lupus erythematosus exemplifies a type III hypersensitivity disease.
A. Type I
B. Type II
C. Type III
D. Type IV
Correct Answer
Type III
Rationale:
Immune complex deposition drives tissue injury in SLE.
Question 10
Multiple myeloma commonly leads to renal insufficiency.
A. Leukemia
B. Lymphoma
C. Myeloma
D. Sarcoma
Correct Answer
Myeloma
Rationale:
Light‑chain deposition damages renal tubules, causing renal failure.
PRRE
EMM II U
UMM SS TT U
UDDY
Y M
MAA TT E
ERR II A
A LL SS STUDY COLLECTION: 2025
PATHO 370 - IN CLASS QUIZ 2 (CH. 10, 11, 13, 14, 15)
EXAM QUESTIONS AND CORRECT ANSWERS
WHAT'S INSIDE:
Latest 2025/2026 Questions
Verified Correct Answers Highlighted for Easy Learning
Detailed Explanations & Rationales for Better Understanding
Proven to Boost Grades and Exam Confidence
Covers All Essential Topics and Core Concepts
Perfect for Quick Revision and Last-Minute Review
Question 1
Which laboratory finding confirms iron‑deficiency anemia?
A. Elevated serum ferritin
B. Decreased total iron‑binding capacity
C. Elevated total iron‑binding capacity
D. Increased mean corpuscular hemoglobin concentration
Correct Answer
Elevated total iron‑binding capacity
Rationale:
TIBC rises when iron stores are depleted, indicating iron deficiency.
,Question 2
A newborn with hemophilia B lacks functional factor IX.
A. Factor VIII
B. Factor IX
C. Factor XI
D. Factor XII
Correct Answer
Factor IX
Rationale:
Hemophilia B is caused by deficiency of clotting factor IX.
Question 3
The Philadelphia chromosome creates the BCR‑ABL fusion gene.
A. c‑myc
B. BCR‑ABL
C. JAK2
D. PML‑RARα
Correct Answer
BCR‑ABL
Rationale:
t(9;22) translocation fuses BCR and ABL, driving chronic myeloid leukemia.
Question 4
Which vitamin deficiency causes macrocytic, megaloblastic anemia?
A. Vitamin B12
B. Vitamin C
C. Vitamin D
D. Vitamin K
Correct Answer
Vitamin B12
Rationale:
B12 deficiency impairs DNA synthesis, producing large, immature red cells.
,Question 5
Erythropoietin therapy is most effective for anemia of chronic kidney disease.
A. Iron supplements
B. Erythropoietin administration
C. Folic acid
D. Vitamin B12 injections
Correct Answer
Erythropoietin administration
Rationale:
Kidney failure reduces endogenous erythropoietin, requiring exogenous replacement.
Question 6
The most serious complication of intensive chemotherapy is infection.
A. Mucositis
B. Neurotoxicity
C. Infection
D. Hair loss
Correct Answer
Infection
Rationale:
Myelosuppression predisposes patients to severe bacterial and fungal infections.
Question 7
Type IV hypersensitivity reactions are mediated by T‑cell–dependent mechanisms.
A. Type I
B. Type II
C. Type III
D. Type IV
Correct Answer
Type IV
Rationale:
Delayed‑type hypersensitivity involves sensitized T‑cells without antibody involvement.
, Question 8
Which lab values are decreased in iron‑deficiency anemia? (Select all that apply)
A. MCV
B. MCH
C. MCHC
D. RDW
Correct Answer
MCV
Rationale:
Iron deficiency reduces hemoglobin content, lowering mean corpuscular volume.
Question 9
Systemic lupus erythematosus exemplifies a type III hypersensitivity disease.
A. Type I
B. Type II
C. Type III
D. Type IV
Correct Answer
Type III
Rationale:
Immune complex deposition drives tissue injury in SLE.
Question 10
Multiple myeloma commonly leads to renal insufficiency.
A. Leukemia
B. Lymphoma
C. Myeloma
D. Sarcoma
Correct Answer
Myeloma
Rationale:
Light‑chain deposition damages renal tubules, causing renal failure.
