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ASCP Hematology Exam – MLT (2025/2026 Update) | Verified Questions and Answers with Detailed Rationales | Grade A

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This updated ASCP Hematology Exam review for MLT candidates (2025/2026) provides 100% verified questions and answers with detailed explanations and rationales. It covers all key hematology concepts tested on the ASCP exam, including blood cell morphology, hematopoiesis, hemostasis, anemia classification, coagulation, and laboratory techniques. Perfect for students and professionals preparing for the ASCP MLT certification, this resource ensures a deep understanding of both theory and practical applications.

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Institución
ASCP Hematology
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ASCP Hematology

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Subido en
10 de noviembre de 2025
Número de páginas
32
Escrito en
2025/2026
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Examen
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ASCP Hematology Exam - MLT |Latest
2025/ 2026 Update | Questions and Answers |
100% verified Elaborations with Rationales
|Grade A
The light-colored zone adjacent to the nucleus in a plasmacyte is the:


A. ribosome
B. chromatin
C. mitochondria
D. Golgi area
D. Golgi area




The majority of the iron in an adult is found as a constituent of:


A. hemoglobin
B. hemosiderin
C. myoglobin
D. transferrin
A. hemoglobin

, ASCP Hematology Exam - MLT |Latest
2025/ 2026 Update | Questions and Answers |
100% verified Elaborations with Rationales
|Grade A
The main function of the hexose monophosphate shunt in the erythrocyte is to:


A. reglate the level of 2,3-DPG
B. provide reduced glutathione to prevent oxidation of hemoglobin
C. prevent the reduction of heme iron
D. provide energy for membrane maintenance
B. provide the level 2,3-DPG




In order for hemoglobin to combine reversibly with oxygen, the iron must be:


A. complexed with haptoglobin
B. freely circulating in the cytoplasm
C. attached to transferrin
D. in the ferrous state
D. in the ferrous state

, ASCP Hematology Exam - MLT |Latest
2025/ 2026 Update | Questions and Answers |
100% verified Elaborations with Rationales
|Grade A
In which of the following disease states are teardrop cells and adnormal platelets
most characteristically seen?


A. hemolytic anemia
B. multiple myeloma
C. G-6-PD deficiency
D. myeloid metaplasma
D. myeloid metaplasia




In the normal adult, the spleen acts as a site for:


A. storage of red blood cells
B. production of red blood cells
C. synthesis of erythropoietin
D. removal of imperfect and aging cells
D. removal of imperfect and aging cells

, ASCP Hematology Exam - MLT |Latest
2025/ 2026 Update | Questions and Answers |
100% verified Elaborations with Rationales
|Grade A
After removal of red blood cells from the circulation hemoglobin is broken down
into:


A. iron, porphyrin, and amino acids
B. iron, protoporphyrin, and globin
C. heme, protoporphyrin, and amino acids
D. heme, hemoseridin, and globin
B. iron, protoporphyrin, and globin




Heinz bodies are:


A. readily identified with polychrome stains
B. rarely found in glucose-6-phosphate dehydrogenase deficient erythrocytes
C. closely associated with spherocytes
D. denatured hemoglobin inclusions that are readily removed by the spleen
D. denatured hemoglobin inclusions that are readily removed by the spleen
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