NGR6141 ADVANCED
PATHOPHYSIOLOGY EXAM 1 2025/2026
QUESTIONS AND ANSWERS 100% PASS
A major characteristic of type 1 diabetes is - ANS autoimmune
Secretion of ADH and the perception of thirst is stimulated by? - ANS increase in plasma
osmolality
What physiological change occurs during heat exhaustion? - ANS Hemoconcentration occurs
because of the loss of salt and water
A malfunction in DNA methylation can lead to? - ANS cancer
Which statement is true concerning IgM? - ANS IgM is the first antibody produced during the
initial response to an antigen
The loss of ATP during ischemia causes cells to? - ANS Swell because of the influx of sodium
chloride
Obesity causes a greater risk of dehydration because? - ANS Adipose cells contain little water
because fat is water repelling
1 @COPYRIGHT 2025/2026
, In hypoxic injury why does sodium enter the cell and cause swelling? - ANS Because the
there is insufficient ATP to maintain the pump that keeps sodium out of the cell
Single most common cause of cellular injury - ANS Hypoxic
Lead poisoning affects the nervous system by? - ANS Interfering with the function of
neurotransmitters
Which risk factor for hypertension is influenced by genetics and lifestyle - ANS Obesity
Thirst activates osmoreceptors by an increase in which blood plasma? - ANS By an increase in
the osmotic pressure of the plasma
Which characteristic is the most important determinant of immunogenicity when considering
the antigen? - ANS Foreignness
Carbon monoxide causes tissue damage by? - ANS Binding to hemoglobin so that it cannot
carry oxygen
When a child inherits a disease that is autosomal recessive it is from? - ANS both parents
The difference between DNA mutation and epigenetic modification is? - ANS Epigenetic
modifications can be reversed
What is true about eukaryotic cells? - ANS Eukaryotic cells contain organelles and histones,
they have a well-defined nucleus, and are larger than prokaryotic cells.
2 @COPYRIGHT 2025/2026
PATHOPHYSIOLOGY EXAM 1 2025/2026
QUESTIONS AND ANSWERS 100% PASS
A major characteristic of type 1 diabetes is - ANS autoimmune
Secretion of ADH and the perception of thirst is stimulated by? - ANS increase in plasma
osmolality
What physiological change occurs during heat exhaustion? - ANS Hemoconcentration occurs
because of the loss of salt and water
A malfunction in DNA methylation can lead to? - ANS cancer
Which statement is true concerning IgM? - ANS IgM is the first antibody produced during the
initial response to an antigen
The loss of ATP during ischemia causes cells to? - ANS Swell because of the influx of sodium
chloride
Obesity causes a greater risk of dehydration because? - ANS Adipose cells contain little water
because fat is water repelling
1 @COPYRIGHT 2025/2026
, In hypoxic injury why does sodium enter the cell and cause swelling? - ANS Because the
there is insufficient ATP to maintain the pump that keeps sodium out of the cell
Single most common cause of cellular injury - ANS Hypoxic
Lead poisoning affects the nervous system by? - ANS Interfering with the function of
neurotransmitters
Which risk factor for hypertension is influenced by genetics and lifestyle - ANS Obesity
Thirst activates osmoreceptors by an increase in which blood plasma? - ANS By an increase in
the osmotic pressure of the plasma
Which characteristic is the most important determinant of immunogenicity when considering
the antigen? - ANS Foreignness
Carbon monoxide causes tissue damage by? - ANS Binding to hemoglobin so that it cannot
carry oxygen
When a child inherits a disease that is autosomal recessive it is from? - ANS both parents
The difference between DNA mutation and epigenetic modification is? - ANS Epigenetic
modifications can be reversed
What is true about eukaryotic cells? - ANS Eukaryotic cells contain organelles and histones,
they have a well-defined nucleus, and are larger than prokaryotic cells.
2 @COPYRIGHT 2025/2026
