Test Bank For Clayton’s Basic Pharmacology for Nurses 19th EditionB
tg tg tg tg tg tg tg tg tg gt
y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Comple
tg tg tg tg tg tg tg tg tg
te
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihngan
tg tg tg tg tg tg tg tg
z: Clayton’s Basic Pharmacology for Nurses, 19th Edition
tg tg tg tg tg tg tg
MULTIPLE CHOICE tg
1. Which name identifies a drug listed by the US Food an
tg tg tg tg tg tg tg tg tg tg
dDrug Administration (FDA)?
tg tg tg
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C tg
The official name is the name under which a drug is listed
tg tg tg tg t g tg tg tg tg tg tg tg
by the FDA. The brand name, or trademark, is the name giv
tg tg tg tg tg tg tg tg tg tg tg
en to a drug by its manufacturer. The nonproprietary, or gen
tg tg tg tg tg tg tg tg tg tg
eric, name is provided by the United States Adopted Names
tg tg tg tg tg tg tg tg tg t
Council.
g
DIF: Cognitive Level: Knowledge REF: p. 9 tg tg tg tg
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Car
tg tg tg tg tg tg tg tg
eEnvironment TOP: Nursing Process Step: Assessment
tg tg t g tg tg tg
CON: tg
Patient Education tg
2. Which source contains information specific to nutritional supplements?
tg tg tg tg tg tg tg
a. USP Dictionary of USAN &International Drug Names
tg tg tg tg tg tg tg
b. Natural Medicines Comprehensive Database tg tg tg
c. United States Pharmacopoeia/National Formulary (USP NF)
tg tg tg tg tg
d. Drug Interaction Facts tg tg
ANS: C tg
United States Pharmacopoeia/National Formulary contains information specific to nutritional
tg tg tg tg tg tg tg tg tg
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
names, pronunciation guide, and possible future FDA approved drugs; it does not include nut
tg tg tg tg tg tg tg tg tg tg tg tg tg
ritional supplements. Natural Medicines Comprehensive Database contains
tg tg tg tg tg tg
evidence-
based information on herbal medicines and herbal combination products; it does notinclude inf
tg tg tg tg tg tg tg tg tg tg tg tg tg
ormation specific to nutritional supplements. Drug Interaction Facts contains comprehensive
tg tg tg tg tg tg tg tg tg t
ginformation on drug interaction facts; it does not include nutritional supplements.
tg tg tg tg tg tg tg tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 4 tg tg t g tg
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
tg tg tg tg tg tg tg tg
grity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
t g tg tg tg t g tg tg tg
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
tg tg tg tg tg tg tg tg tg tg tg tg tg
a. Drug Facts and Comparisons tg tg tg
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editio
tg tg tg tg tg tg tg tg tg 3
n
b. Drug Interaction Facts tg tg
c. Handbook on Injectable Drugs tg tg tg
d. Martindale—The Complete Drug Reference tg tg tg
ANS: A tg
Drug Facts and Comparisons contains drug monographs that describe all drugs in at
tg tg tg tg tg tg tg tg tg tg tg tg tg
herapeutic class. Monographs are formatted as tables to allow comparison of similarpr
tg tg tg tg tg tg tg tg tg tg tg tg
oducts, brand names, manufacturers, cost indices, and available dosage forms Online
tg tg tg tg tg tg tg tg tg tg t
version is available.
g tg tg
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 tg tg t g tg tg tg
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
tgtgt g t g tg tg tg tg tg
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
t g tg tg tg t g tg tg tg tg tg tg
4. Which drug reference contains monographs about virtually every single-
tg tg tg tg tg tg tg tg
entity drug availablein the United States and describes therapeutic uses of drugs, including a
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
pproved and unapproved uses? tg tg tg
a. Martindale: The Complete Drug Reference tg tg tg tg
b. AHFS Drug Information tg tg
c. Drug Reference tg
d. Drug Facts and Comparisons tg tg tg
ANS: B tg
AHFS Drug Information contains monographs about virtually every single-
tg tg tg tg tg tg tg tg
entity drug available in the United States and describes therapeutic uses of drugs, including ap
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
proved andunapproved uses. tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 tg tg t g tg tg tg
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
tgtgt g t g tg tg tg tg tg
TOP: Nursing Process Step: Planning
t g CON: Safety | Patient Education | Clinical Judgment
tg tg tg t g tg tg tg tg tg tg
5. Which online drug reference makes available to healthcare providers and the public a sta
tg tg tg tg tg tg tg tg tg tg tg tg tg
ndard, comprehensive, up-to-date look up and downloadable resource about medicines?
tg tg tg tg tg tg tg tg tg
a. American Drug Index tg tg
b. American Hospital Formulary tg tg
c. DailyMed
d. Drug Reference tg
ANS: C tg
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
tg tg tg tg tg tg tg tg tg tg tg tg
up-to-
date look up and downloadable resource about medicines. The American Drug Index isnot ap
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
propriate for patient use. The American Hospital Formulary is not appropriate for patient us
tg tg tg tg tg tg tg tg tg tg tg tg tg
e. The drug reference is not appropriate for patient use.
tg tg tg tg tg tg tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 tg tg t g tg tg tg tg
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
tg tg tg tg tg tg tg tg
grity
TOP: Nursing Process Step: Implementation
tg tg tg tg
CON: Safety | Patient Education | Clinical Judgment
t g tg tg tg tg tg tg
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
a. Federal Food, Drug, and Cosmetic Act (1938) tg tg tg tg tg tg
b. Durham Humphrey Amendment (1952) tg tg tg
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editio
tg tg tg tg tg tg tg tg tg 4
n
c. Controlled Substances Act (1970) tg tg tg
d. Kefauver Harris Drug Amendment (1962) tg tg tg tg
ANS: A tg
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the saf
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ety of all drugs before marketing. Later amendments and acts helped tighten FDA control an
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
d ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that can
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
not be used safely without medical supervision and restricts their sale to prescription by a lic
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ensed practitioner. The Controlled Substances Act addresses only controlled substances andth
tg tg tg tg tg tg tg tg tg tg tg
eir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greaterdr
tg tg tg tg tg tg tg tg tg tg tg tg
ug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their pro
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ducts before marketing them.
tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 tg tg tg tg tg tg
OBJ: 5 t g
NAT: NCLEX Client Needs Category: Physiological Integrit tg tg tg tg tg tg
yTOP: Nursing Process Step: Assessment
tg tg tg tg tg
CON: Safety | Patient Education | Evidence | Health Care Law
t g tg tg tg tg tg tg tg tg tg
7. Which classification does meperidine (Demerol) fall under?
tg tg tg tg tg tg
a. I
b. II
c. III
d. IV
ANS: B tg
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
tg tg tg tg tg tg tg tg tg tg tg tg tg
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may l
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ead to low to moderate physical dependence or high psychological dependence. Schedule IV
tg tg tg tg tg tg tg tg tg tg tg tg tg
drugs have low potential for abuse. Use may lead to limited physical or psychological depen
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
dence.
DIF: Cognitive Level: Knowledge REF: p. 10 tg tg t g tg
OBJ: 2NAT: NCLEX Client Needs Category: Safe, Effective Cartg tg tg tg tg tg tg tg tg
e Environment
tg
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
t g tg tg tg t g tg tg tg tg tg
8. Which action would the FDA take to expedite drug development and approval for an outbreak
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
of smallpox?
tg
a. List smallpox as a health orphan disease.tg tg tg tg tg tg
b. Omit the preclinical research phase. tg tg tg tg
c. Extend the clinical research phase. tg tg tg tg
d. Fast track the investigational drug. tg tg tg tg
ANS: D tg
Once the Investigational New Drug Application has been approved, the drug can receive hig
tg tg tg tg tg tg tg tg tg tg tg tg tg
hest priority within the agency, which is called fast tracking. A smallpox outbreak would bec
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ome a priority concern in the world. Orphan diseases are not researched in a priority manner.
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg t
gPreclinical research is not omitted. Extending any phase of the research would meana longer
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
time to develop a vaccine. The FDA must ensure that all phases of the preclinical andclinical re
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
search phase have been completed in a safe manner.
tg tg tg tg tg tg tg tg
DIF: Cognitive Level: Knowledge tg tg REF: p. 7 tgtgtg tg OBJ: 5 tg
tg tg tg tg tg tg tg tg tg gt
y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Comple
tg tg tg tg tg tg tg tg tg
te
,Chapter 01: Drug Definitions, Standards, and Information Sources Willihngan
tg tg tg tg tg tg tg tg
z: Clayton’s Basic Pharmacology for Nurses, 19th Edition
tg tg tg tg tg tg tg
MULTIPLE CHOICE tg
1. Which name identifies a drug listed by the US Food an
tg tg tg tg tg tg tg tg tg tg
dDrug Administration (FDA)?
tg tg tg
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C tg
The official name is the name under which a drug is listed
tg tg tg tg t g tg tg tg tg tg tg tg
by the FDA. The brand name, or trademark, is the name giv
tg tg tg tg tg tg tg tg tg tg tg
en to a drug by its manufacturer. The nonproprietary, or gen
tg tg tg tg tg tg tg tg tg tg
eric, name is provided by the United States Adopted Names
tg tg tg tg tg tg tg tg tg t
Council.
g
DIF: Cognitive Level: Knowledge REF: p. 9 tg tg tg tg
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Car
tg tg tg tg tg tg tg tg
eEnvironment TOP: Nursing Process Step: Assessment
tg tg t g tg tg tg
CON: tg
Patient Education tg
2. Which source contains information specific to nutritional supplements?
tg tg tg tg tg tg tg
a. USP Dictionary of USAN &International Drug Names
tg tg tg tg tg tg tg
b. Natural Medicines Comprehensive Database tg tg tg
c. United States Pharmacopoeia/National Formulary (USP NF)
tg tg tg tg tg
d. Drug Interaction Facts tg tg
ANS: C tg
United States Pharmacopoeia/National Formulary contains information specific to nutritional
tg tg tg tg tg tg tg tg tg
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
names, pronunciation guide, and possible future FDA approved drugs; it does not include nut
tg tg tg tg tg tg tg tg tg tg tg tg tg
ritional supplements. Natural Medicines Comprehensive Database contains
tg tg tg tg tg tg
evidence-
based information on herbal medicines and herbal combination products; it does notinclude inf
tg tg tg tg tg tg tg tg tg tg tg tg tg
ormation specific to nutritional supplements. Drug Interaction Facts contains comprehensive
tg tg tg tg tg tg tg tg tg t
ginformation on drug interaction facts; it does not include nutritional supplements.
tg tg tg tg tg tg tg tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 4 tg tg t g tg
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
tg tg tg tg tg tg tg tg
grity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
t g tg tg tg t g tg tg tg
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
tg tg tg tg tg tg tg tg tg tg tg tg tg
a. Drug Facts and Comparisons tg tg tg
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editio
tg tg tg tg tg tg tg tg tg 3
n
b. Drug Interaction Facts tg tg
c. Handbook on Injectable Drugs tg tg tg
d. Martindale—The Complete Drug Reference tg tg tg
ANS: A tg
Drug Facts and Comparisons contains drug monographs that describe all drugs in at
tg tg tg tg tg tg tg tg tg tg tg tg tg
herapeutic class. Monographs are formatted as tables to allow comparison of similarpr
tg tg tg tg tg tg tg tg tg tg tg tg
oducts, brand names, manufacturers, cost indices, and available dosage forms Online
tg tg tg tg tg tg tg tg tg tg t
version is available.
g tg tg
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 tg tg t g tg tg tg
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
tgtgt g t g tg tg tg tg tg
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
t g tg tg tg t g tg tg tg tg tg tg
4. Which drug reference contains monographs about virtually every single-
tg tg tg tg tg tg tg tg
entity drug availablein the United States and describes therapeutic uses of drugs, including a
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
pproved and unapproved uses? tg tg tg
a. Martindale: The Complete Drug Reference tg tg tg tg
b. AHFS Drug Information tg tg
c. Drug Reference tg
d. Drug Facts and Comparisons tg tg tg
ANS: B tg
AHFS Drug Information contains monographs about virtually every single-
tg tg tg tg tg tg tg tg
entity drug available in the United States and describes therapeutic uses of drugs, including ap
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
proved andunapproved uses. tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 tg tg t g tg tg tg
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
tgtgt g t g tg tg tg tg tg
TOP: Nursing Process Step: Planning
t g CON: Safety | Patient Education | Clinical Judgment
tg tg tg t g tg tg tg tg tg tg
5. Which online drug reference makes available to healthcare providers and the public a sta
tg tg tg tg tg tg tg tg tg tg tg tg tg
ndard, comprehensive, up-to-date look up and downloadable resource about medicines?
tg tg tg tg tg tg tg tg tg
a. American Drug Index tg tg
b. American Hospital Formulary tg tg
c. DailyMed
d. Drug Reference tg
ANS: C tg
DailyMed makes available to healthcare providers and the public a standard, comprehensive,
tg tg tg tg tg tg tg tg tg tg tg tg
up-to-
date look up and downloadable resource about medicines. The American Drug Index isnot ap
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
propriate for patient use. The American Hospital Formulary is not appropriate for patient us
tg tg tg tg tg tg tg tg tg tg tg tg tg
e. The drug reference is not appropriate for patient use.
tg tg tg tg tg tg tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 tg tg t g tg tg tg tg
OBJ: 3NAT: NCLEX Client Needs Category: Physiological Inte
tg tg tg tg tg tg tg tg
grity
TOP: Nursing Process Step: Implementation
tg tg tg tg
CON: Safety | Patient Education | Clinical Judgment
t g tg tg tg tg tg tg
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
a. Federal Food, Drug, and Cosmetic Act (1938) tg tg tg tg tg tg
b. Durham Humphrey Amendment (1952) tg tg tg
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editio
tg tg tg tg tg tg tg tg tg 4
n
c. Controlled Substances Act (1970) tg tg tg
d. Kefauver Harris Drug Amendment (1962) tg tg tg tg
ANS: A tg
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the saf
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ety of all drugs before marketing. Later amendments and acts helped tighten FDA control an
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
d ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that can
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
not be used safely without medical supervision and restricts their sale to prescription by a lic
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ensed practitioner. The Controlled Substances Act addresses only controlled substances andth
tg tg tg tg tg tg tg tg tg tg tg
eir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greaterdr
tg tg tg tg tg tg tg tg tg tg tg tg
ug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their pro
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ducts before marketing them.
tg tg tg
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 tg tg tg tg tg tg
OBJ: 5 t g
NAT: NCLEX Client Needs Category: Physiological Integrit tg tg tg tg tg tg
yTOP: Nursing Process Step: Assessment
tg tg tg tg tg
CON: Safety | Patient Education | Evidence | Health Care Law
t g tg tg tg tg tg tg tg tg tg
7. Which classification does meperidine (Demerol) fall under?
tg tg tg tg tg tg
a. I
b. II
c. III
d. IV
ANS: B tg
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
tg tg tg tg tg tg tg tg tg tg tg tg tg
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may l
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ead to low to moderate physical dependence or high psychological dependence. Schedule IV
tg tg tg tg tg tg tg tg tg tg tg tg tg
drugs have low potential for abuse. Use may lead to limited physical or psychological depen
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
dence.
DIF: Cognitive Level: Knowledge REF: p. 10 tg tg t g tg
OBJ: 2NAT: NCLEX Client Needs Category: Safe, Effective Cartg tg tg tg tg tg tg tg tg
e Environment
tg
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
t g tg tg tg t g tg tg tg tg tg
8. Which action would the FDA take to expedite drug development and approval for an outbreak
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
of smallpox?
tg
a. List smallpox as a health orphan disease.tg tg tg tg tg tg
b. Omit the preclinical research phase. tg tg tg tg
c. Extend the clinical research phase. tg tg tg tg
d. Fast track the investigational drug. tg tg tg tg
ANS: D tg
Once the Investigational New Drug Application has been approved, the drug can receive hig
tg tg tg tg tg tg tg tg tg tg tg tg tg
hest priority within the agency, which is called fast tracking. A smallpox outbreak would bec
tg tg tg tg tg tg tg tg tg tg tg tg tg tg
ome a priority concern in the world. Orphan diseases are not researched in a priority manner.
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg t
gPreclinical research is not omitted. Extending any phase of the research would meana longer
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
time to develop a vaccine. The FDA must ensure that all phases of the preclinical andclinical re
tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg tg
search phase have been completed in a safe manner.
tg tg tg tg tg tg tg tg
DIF: Cognitive Level: Knowledge tg tg REF: p. 7 tgtgtg tg OBJ: 5 tg
