Complete Solutions
Specific vs nonspecific immunity?
Specific adaptive, nonspecific innate.
3 lines of defense?
Barriers, innate cells, adaptive immunity.
First line defenses?
Skin, mucous, secretions.
Phagocytic cells function?
Engulf microbes.
NK cells function?
Kill virus-infected/tumor cells.
Interferons function?
Warn nearby cells, antiviral response.
Complement effects?
Opsonization, inflammation, cytolysis.
Inflammation?
Swelling, heat, redness, pain.
Pyrexia?
Fever raises metabolism, kills microbes.
,Specific immunity traits?
Specificity and memory.
Leukocytes in adaptive immunity?
T cells, B cells.
Key lymphocyte trait?
Antigen-specific receptors.
Where T cells mature?
Thymus.
Two main T cell types?
Helper, cytotoxic.
Cell-mediated immunity cells?
Cytotoxic T cells.
Destroy infected cells?
Cytotoxic T cells.
Recruit immune cells?
Helper T cells.
T cells bind MHC-I?
Cytotoxic T cells.
T cells bind MHC-II?
Helper T cells.
Where B cells mature?
, Bone marrow.
Antigen-presenting cells?
Macrophages, dendritic cells, B cells.
APCs work with?
Helper T cells.
Role of MHC proteins?
Present antigens to T cells.
MHC-II found on?
APCs.
MHC-II presents to?
Helper T cells.
How macrophages present antigens?
Engulf, process, display via MHC-II.
MHC-I found on?
All nucleated cells.
MHC-I presents to?
Cytotoxic T cells.
Sequence of cell-mediated immunity?
APC → Helper T → Cytotoxic T.
Role of memory T cells?
Faster future response.