UWSA 2 FINAL PAPER UPDATED QUESTIONS AND
ANSWERS RATED A+
✔✔Failed obliteration of the omphalomesenteric duct - ✔✔Meckel's diverticulum
✔✔Bilious emesis, abdominal pain, and bloody stools - ✔✔Volvulus--> bowel may
rotate incompletely round the SMA
✔✔Severe intermittent abdominal pain, vomiting, bloody stools, and palpable abdominal
mass - ✔✔Intussusception
✔✔Finding in HCM - ✔✔Thickened IV septum
Normal coronary arteries
Disordered arrangement of cardiac myofibrils
AS murmur that increases with standing
✔✔A widely split heart sound is heard at the upper sternal border that is accentuated
with inspiration. Where will it be heart on the curve? - ✔✔When the aortic valve closes
A wide split S2 can occur with delayed closure of the pulmonic valve--> RBBB, pulmonic
stenosis, and P HTN. Heard with the closure of the AV.
✔✔When is a BAV heard? - ✔✔When aortic valve opens
✔✔Where is MS heard? - ✔✔When MV opens
✔✔What is needed for removal and replacement of primers with DNA? - ✔✔DNA Pol I
✔✔DNA Pol I - ✔✔Removes RNA primer and replaces it with DNA
✔✔DNA Pol III - ✔✔5' to 3' DNA synthesis
3' to 5' exonuclease
✔✔What do you want for a screening test? - ✔✔High sensitivity and low 1-specificity
(false positives)
✔✔HNPCC - ✔✔Mutation in mismatch repair gene
✔✔Inactivation of nonhomologous end-joining repair - ✔✔Ataxia Telangiectasia
✔✔Gain of function in RET gene - ✔✔MEN 2A/2B
✔✔Medication after transplant that can cause obliterative vasculopathy of afferent
arterioles - ✔✔Tacrolimus
, Causes a dose-dependent rise in BUN and creatinine
✔✔What medication should you not give a patient with Parkinsons? -
✔✔Metoclopramide
✔✔What is the complication of alkaptonuria? - ✔✔Osteoarthropathy
Def in homgentisic acid dioxygenase
Blackening of urine
✔✔Increased resistance to passive elbow flexion and extension and a hand tremor that
disappears with movement - ✔✔PD
✔✔A patient with Afib has a cold and pale right foot without a palpable pulse over the
dorsalis pedis artery. What will be increased in the extracellular space? - ✔✔K+
Na+/K+ pump won't work--> increased IC Na+ and Ca2+ and increased extracellular K+
✔✔Darkly staining cells in a glomerulus - ✔✔JGA cells--> produce renin
✔✔A sample of amniotic fluid is added to a test well containing ethanol. The mixture is
shaken and stable ring of foam appears. What substance? - ✔✔Surfactant-->
composed of phospholipids
✔✔What causes amenorrhea in anorexic patients/ - ✔✔Decreased hypothalamic GnRH
secretion
✔✔Patient with Marfan symptoms, dislocated lens, intellectual delay and history of
sinus venous thrombosis - ✔✔CBS mutation--> homocystinuria
Increased methionine and homocystien
✔✔Pancreatic pseudocyst - ✔✔Collection of fluid with calcifications in the pancreas.
Compresses the IVC
✔✔What primers yield complementary copies of a DNA sequence during PCR? -
✔✔Have to be in 5' to 3' direction
3' end needs to be oriented toward target DNA
✔✔Why is heparin safer than warfarin during pregnancy? - ✔✔Higher water solubility --
> goes not cross the placenta
ANSWERS RATED A+
✔✔Failed obliteration of the omphalomesenteric duct - ✔✔Meckel's diverticulum
✔✔Bilious emesis, abdominal pain, and bloody stools - ✔✔Volvulus--> bowel may
rotate incompletely round the SMA
✔✔Severe intermittent abdominal pain, vomiting, bloody stools, and palpable abdominal
mass - ✔✔Intussusception
✔✔Finding in HCM - ✔✔Thickened IV septum
Normal coronary arteries
Disordered arrangement of cardiac myofibrils
AS murmur that increases with standing
✔✔A widely split heart sound is heard at the upper sternal border that is accentuated
with inspiration. Where will it be heart on the curve? - ✔✔When the aortic valve closes
A wide split S2 can occur with delayed closure of the pulmonic valve--> RBBB, pulmonic
stenosis, and P HTN. Heard with the closure of the AV.
✔✔When is a BAV heard? - ✔✔When aortic valve opens
✔✔Where is MS heard? - ✔✔When MV opens
✔✔What is needed for removal and replacement of primers with DNA? - ✔✔DNA Pol I
✔✔DNA Pol I - ✔✔Removes RNA primer and replaces it with DNA
✔✔DNA Pol III - ✔✔5' to 3' DNA synthesis
3' to 5' exonuclease
✔✔What do you want for a screening test? - ✔✔High sensitivity and low 1-specificity
(false positives)
✔✔HNPCC - ✔✔Mutation in mismatch repair gene
✔✔Inactivation of nonhomologous end-joining repair - ✔✔Ataxia Telangiectasia
✔✔Gain of function in RET gene - ✔✔MEN 2A/2B
✔✔Medication after transplant that can cause obliterative vasculopathy of afferent
arterioles - ✔✔Tacrolimus
, Causes a dose-dependent rise in BUN and creatinine
✔✔What medication should you not give a patient with Parkinsons? -
✔✔Metoclopramide
✔✔What is the complication of alkaptonuria? - ✔✔Osteoarthropathy
Def in homgentisic acid dioxygenase
Blackening of urine
✔✔Increased resistance to passive elbow flexion and extension and a hand tremor that
disappears with movement - ✔✔PD
✔✔A patient with Afib has a cold and pale right foot without a palpable pulse over the
dorsalis pedis artery. What will be increased in the extracellular space? - ✔✔K+
Na+/K+ pump won't work--> increased IC Na+ and Ca2+ and increased extracellular K+
✔✔Darkly staining cells in a glomerulus - ✔✔JGA cells--> produce renin
✔✔A sample of amniotic fluid is added to a test well containing ethanol. The mixture is
shaken and stable ring of foam appears. What substance? - ✔✔Surfactant-->
composed of phospholipids
✔✔What causes amenorrhea in anorexic patients/ - ✔✔Decreased hypothalamic GnRH
secretion
✔✔Patient with Marfan symptoms, dislocated lens, intellectual delay and history of
sinus venous thrombosis - ✔✔CBS mutation--> homocystinuria
Increased methionine and homocystien
✔✔Pancreatic pseudocyst - ✔✔Collection of fluid with calcifications in the pancreas.
Compresses the IVC
✔✔What primers yield complementary copies of a DNA sequence during PCR? -
✔✔Have to be in 5' to 3' direction
3' end needs to be oriented toward target DNA
✔✔Why is heparin safer than warfarin during pregnancy? - ✔✔Higher water solubility --
> goes not cross the placenta
