GMS6552 Exam 2026 Questions and
Answers
which type of receptor most often utilizes second messenger systems in its
signaling?
•kinase linked receptors
•channel linked receptors
•nuclear receptors
•G protein coupled receptors - Correct answer-G protein coupled receptors
assume you have receptor antagonists that are able to stop receptor signaling
immediately. for which type of receptor would it take the longest to see the effects
of your drug at the cellular level?
•kinase linked receptors
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,•channel linked receptors
•nuclear receptors
•G protein coupled receptors - Correct answer-nuclear receptors
for which type of receptor would having adequate membrane permeability of an
agonist be most critical?
•kinase linked receptors
•channel linked receptors
•nuclear receptors
•G protein coupled receptors - Correct answer-nuclear receptors
is it more likely for a G protein coupled receptor agonist to bind near the N or C
terminus of the receptor?
•N terminus
•C terminus - Correct answer-N terminus
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,is it more likely to find a GCPR bound to a G protein that is also bound to GTP or
GDP?
•GTP
•GDP - Correct answer-GDP
which protein ultimately is translocated from the cytoplasm to the nucleus as a
result of JAK signaling?
•JAK
•GRB2
•SH2
•PI3K
•STAT - Correct answer-STAT
where in relation to the protein ciding region of a gene are the binding sites that
become occupied by nuclear receptors?
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, •upstream
•within the coding region
•downstream - Correct answer-upstream
the levels of which second messenger would be expected to increase following
administration of nitroglycerin?
•Ca2+
•cAMP
•carbon monoxide
•diacylglycerol
•cGMP
•kaboom! - Correct answer-cGMP
does TGF-beta treatment cause cells to grow more or less in the soft agar assay?
•more
•less - Correct answer-more
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Answers
which type of receptor most often utilizes second messenger systems in its
signaling?
•kinase linked receptors
•channel linked receptors
•nuclear receptors
•G protein coupled receptors - Correct answer-G protein coupled receptors
assume you have receptor antagonists that are able to stop receptor signaling
immediately. for which type of receptor would it take the longest to see the effects
of your drug at the cellular level?
•kinase linked receptors
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
,•channel linked receptors
•nuclear receptors
•G protein coupled receptors - Correct answer-nuclear receptors
for which type of receptor would having adequate membrane permeability of an
agonist be most critical?
•kinase linked receptors
•channel linked receptors
•nuclear receptors
•G protein coupled receptors - Correct answer-nuclear receptors
is it more likely for a G protein coupled receptor agonist to bind near the N or C
terminus of the receptor?
•N terminus
•C terminus - Correct answer-N terminus
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,is it more likely to find a GCPR bound to a G protein that is also bound to GTP or
GDP?
•GTP
•GDP - Correct answer-GDP
which protein ultimately is translocated from the cytoplasm to the nucleus as a
result of JAK signaling?
•JAK
•GRB2
•SH2
•PI3K
•STAT - Correct answer-STAT
where in relation to the protein ciding region of a gene are the binding sites that
become occupied by nuclear receptors?
©COPYRIGHT 2025, ALL RIGHTS RESERVED 3
, •upstream
•within the coding region
•downstream - Correct answer-upstream
the levels of which second messenger would be expected to increase following
administration of nitroglycerin?
•Ca2+
•cAMP
•carbon monoxide
•diacylglycerol
•cGMP
•kaboom! - Correct answer-cGMP
does TGF-beta treatment cause cells to grow more or less in the soft agar assay?
•more
•less - Correct answer-more
©COPYRIGHT 2025, ALL RIGHTS RESERVED 4
