CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Ch. 1 — Disease Prevention & Health Promotion (5 items)
Item 1
Reference
Ch. 1 — Disease Prevention & Health Promotion
,Question Stem
A 55-year-old man with a 30–pack-year smoking history
presents for an annual exam. He says he quit smoking 5 years
ago. His BMI is 27 kg/m². Which screening intervention is most
supported by CMDT 2026 to reduce his lung-cancer mortality
risk?
Options
A. Low-dose CT chest screening every year
B. Chest radiograph every year
C. Sputum cytology annually
D. No screening required because he quit smoking over 3 years
ago
Correct Answer
A
Rationales
• A (Correct): CMDT recommends annual low-dose CT
(LDCT) screening for individuals meeting age and smoking-
history criteria because LDCT reduces lung-cancer
mortality compared with chest radiography or no
screening. Annual testing is appropriate for high-risk
patients who meet guideline thresholds.
• B: Chest radiography is less sensitive and not
recommended for lung-cancer screening; it does not
reduce mortality.
, • C: Sputum cytology has low sensitivity and is not
recommended as a primary screening strategy in
contemporary guidelines.
• D: Smoking cessation reduces risk but prior heavy smokers
who meet age/pack-year criteria remain candidates for
LDCT despite quitting; time since cessation affects
eligibility but >5 years does not automatically exclude
screening if other criteria met.
Teaching Point
Annual low-dose CT reduces lung cancer mortality in high-risk
adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
Item 2
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 30-year-old woman planning pregnancy asks which vaccine is
most important to ensure before becoming pregnant to reduce
fetal risk. According to CMDT 2026, which vaccine should be
administered prior to conception?
, Options
A. Live attenuated MMR vaccine if nonimmune
B. Inactivated influenza vaccine during pregnancy
C. Td booster during first trimester
D. Live intranasal influenza vaccine during pregnancy
Correct Answer
A
Rationales
• A (Correct): CMDT advises verifying rubella immunity and
administering MMR (live attenuated) to nonimmune
persons before pregnancy because rubella infection in
pregnancy can cause severe fetal anomalies. Live vaccines
are contraindicated during pregnancy, so vaccination prior
to conception is required.
• B: Inactivated influenza vaccine is recommended during
pregnancy but is given when pregnant; it is not a
preconception-only vaccine.
• C: Td may be given per schedule, but rubella/MMR
immunization to prevent congenital rubella syndrome is
highest priority preconception if nonimmune.
• D: Live intranasal influenza vaccine is contraindicated in
pregnancy and not recommended; inactivated injectable
influenza vaccine is preferred.
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Ch. 1 — Disease Prevention & Health Promotion (5 items)
Item 1
Reference
Ch. 1 — Disease Prevention & Health Promotion
,Question Stem
A 55-year-old man with a 30–pack-year smoking history
presents for an annual exam. He says he quit smoking 5 years
ago. His BMI is 27 kg/m². Which screening intervention is most
supported by CMDT 2026 to reduce his lung-cancer mortality
risk?
Options
A. Low-dose CT chest screening every year
B. Chest radiograph every year
C. Sputum cytology annually
D. No screening required because he quit smoking over 3 years
ago
Correct Answer
A
Rationales
• A (Correct): CMDT recommends annual low-dose CT
(LDCT) screening for individuals meeting age and smoking-
history criteria because LDCT reduces lung-cancer
mortality compared with chest radiography or no
screening. Annual testing is appropriate for high-risk
patients who meet guideline thresholds.
• B: Chest radiography is less sensitive and not
recommended for lung-cancer screening; it does not
reduce mortality.
, • C: Sputum cytology has low sensitivity and is not
recommended as a primary screening strategy in
contemporary guidelines.
• D: Smoking cessation reduces risk but prior heavy smokers
who meet age/pack-year criteria remain candidates for
LDCT despite quitting; time since cessation affects
eligibility but >5 years does not automatically exclude
screening if other criteria met.
Teaching Point
Annual low-dose CT reduces lung cancer mortality in high-risk
adults.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1.
Item 2
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 30-year-old woman planning pregnancy asks which vaccine is
most important to ensure before becoming pregnant to reduce
fetal risk. According to CMDT 2026, which vaccine should be
administered prior to conception?
, Options
A. Live attenuated MMR vaccine if nonimmune
B. Inactivated influenza vaccine during pregnancy
C. Td booster during first trimester
D. Live intranasal influenza vaccine during pregnancy
Correct Answer
A
Rationales
• A (Correct): CMDT advises verifying rubella immunity and
administering MMR (live attenuated) to nonimmune
persons before pregnancy because rubella infection in
pregnancy can cause severe fetal anomalies. Live vaccines
are contraindicated during pregnancy, so vaccination prior
to conception is required.
• B: Inactivated influenza vaccine is recommended during
pregnancy but is given when pregnant; it is not a
preconception-only vaccine.
• C: Td may be given per schedule, but rubella/MMR
immunization to prevent congenital rubella syndrome is
highest priority preconception if nonimmune.
• D: Live intranasal influenza vaccine is contraindicated in
pregnancy and not recommended; inactivated injectable
influenza vaccine is preferred.
