CURRENT Medical Diagnosis and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Q1
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 72-year-old man presents after stepping on a rusty nail while
gardening. He has no vaccination records and cannot recall
,prior tetanus shots. The wound is deep and contaminated.
Which immediate management is most appropriate to provide
now?
Options
A. No tetanus-specific therapy now; schedule a tetanus booster
in primary care.
B. Give tetanus toxoid-containing vaccine only (Tdap/Td).
C. Administer human tetanus immune globulin (TIG) plus
tetanus toxoid-containing vaccine.
D. Give intravenous antibiotics only; defer immunization.
Correct Answer
C
Rationales
Correct: In a patient with unknown vaccination history and a
severe/contaminated wound, provide passive immunization
with TIG for immediate neutralization and administer tetanus
toxoid-containing vaccine to initiate active immunity. This
provides both immediate protection and long-term
immunologic priming.
A: Unsafe — delaying both passive and active protection risks
tetanus development.
B: Vaccine alone is insufficient for severe wounds when prior
immunization is unknown; passive TIG recommended.
D: Antibiotics treat wound infection but do not prevent tetanus;
immunologic prophylaxis is required.
,Teaching Point
Unknown tetanus history + contaminated wound → TIG +
tetanus toxoid vaccine immediately.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. Google Books
Q2
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 54-year-old woman with well-controlled hypertension asks
whether she should start statin therapy for primary prevention.
Her 10-year ASCVD risk (pooled cohort) is 8.5%. Using risk-
based prevention principles, what is the best recommendation?
Options
A. No statin; recommend lifestyle modification only.
B. Offer moderate-intensity statin therapy after shared decision-
making.
C. Start high-intensity statin therapy immediately.
D. Start aspirin daily for primary prevention instead of statin.
Correct Answer
B
, Rationales
Correct: For intermediate 10-year ASCVD risk (≈7.5–20%),
guidelines and prevention frameworks support offering
moderate-intensity statin therapy after patient-centered shared
decision-making about risks and benefits.
A: Lifestyle is important but alone may be insufficient given
intermediate risk.
C: High-intensity statin is typically reserved for higher risk or
established ASCVD.
D: Aspirin for primary prevention is no longer routinely
recommended when bleeding risk outweighs benefit; statin is
preferred for ASCVD risk reduction.
Teaching Point
Intermediate ASCVD risk → discuss and offer moderate-
intensity statin therapy.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. Google Books
Q3
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 40-year-old man who smokes 1 ppd and wants to quit asks
which pharmacotherapy most effectively doubles quit rates and
Treatment 2026
65th Edition
Author(s)Maxine A. Papadakis; Michael
W. Rabow; Kenneth R. McQuaid; Paul L.
Nadler; Erika Leemann Price
TEST BANK
Q1
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 72-year-old man presents after stepping on a rusty nail while
gardening. He has no vaccination records and cannot recall
,prior tetanus shots. The wound is deep and contaminated.
Which immediate management is most appropriate to provide
now?
Options
A. No tetanus-specific therapy now; schedule a tetanus booster
in primary care.
B. Give tetanus toxoid-containing vaccine only (Tdap/Td).
C. Administer human tetanus immune globulin (TIG) plus
tetanus toxoid-containing vaccine.
D. Give intravenous antibiotics only; defer immunization.
Correct Answer
C
Rationales
Correct: In a patient with unknown vaccination history and a
severe/contaminated wound, provide passive immunization
with TIG for immediate neutralization and administer tetanus
toxoid-containing vaccine to initiate active immunity. This
provides both immediate protection and long-term
immunologic priming.
A: Unsafe — delaying both passive and active protection risks
tetanus development.
B: Vaccine alone is insufficient for severe wounds when prior
immunization is unknown; passive TIG recommended.
D: Antibiotics treat wound infection but do not prevent tetanus;
immunologic prophylaxis is required.
,Teaching Point
Unknown tetanus history + contaminated wound → TIG +
tetanus toxoid vaccine immediately.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. Google Books
Q2
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 54-year-old woman with well-controlled hypertension asks
whether she should start statin therapy for primary prevention.
Her 10-year ASCVD risk (pooled cohort) is 8.5%. Using risk-
based prevention principles, what is the best recommendation?
Options
A. No statin; recommend lifestyle modification only.
B. Offer moderate-intensity statin therapy after shared decision-
making.
C. Start high-intensity statin therapy immediately.
D. Start aspirin daily for primary prevention instead of statin.
Correct Answer
B
, Rationales
Correct: For intermediate 10-year ASCVD risk (≈7.5–20%),
guidelines and prevention frameworks support offering
moderate-intensity statin therapy after patient-centered shared
decision-making about risks and benefits.
A: Lifestyle is important but alone may be insufficient given
intermediate risk.
C: High-intensity statin is typically reserved for higher risk or
established ASCVD.
D: Aspirin for primary prevention is no longer routinely
recommended when bleeding risk outweighs benefit; statin is
preferred for ASCVD risk reduction.
Teaching Point
Intermediate ASCVD risk → discuss and offer moderate-
intensity statin therapy.
Citation (Simplified APA)
Papadakis et al. (2025). CURRENT Medical Diagnosis &
Treatment 2026 (65th Ed.). Ch. 1. Google Books
Q3
Reference
Ch. 1 — Disease Prevention & Health Promotion
Question Stem
A 40-year-old man who smokes 1 ppd and wants to quit asks
which pharmacotherapy most effectively doubles quit rates and
