ACTUAL EXAM 2025/2026 ACCURATE EXAM COMPLETE
REALQUESTIONS AND CORRECT DETAILED ANSWERS
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ANCC FNP BOARD EXAM
Which type of vaccine boosts immune response better? conjugate vs.
polysaccharide
Answer- conjugate (example: pruner)
Live attenuated (weaned) vaccines
Answer- MMR, Varicella and intranasal Flu-mist. Zostavax is also live.
Shangri is NOT live.
When is rotavirus vaccine contraindicated?
Answer- SCID (severe combined immunodeficiency) or hex
intussusception
Precautions after rotavirus
Answer- hand washing! viral shed in stool in first week post-vaccination
,Shangri: timing and dosing
=/> 50 y/o, 2 doses, 2nd dose two to six months after 1st dose.
Under age 50 y/o gets shingles; think immunocompromised vs. stress.
What month does the CDC release a new vaccination schedule each
year?
Answer- Feb
What s/s are associated with leukemia?
Answer- fever, wt. loss, fatigue, bone pain, bleeding, bruising.
What bloodwork should be obtained in suspected leukemia?
WBCs >20,000 (think through common causes of leukocytosis:
infection, stress, inflammation) --> get a peripheral smear (AKA manual
diff)
Answer- if WBCs >20,000 and with associated anemia;
thrombocytopenia; thrombocytosis; enlarged liver, spleen, or lymph
nodes; or constitutional symptoms.
,Which 2 chronic childhood diagnoses are associated with ALL and
AML?
Answer- Downs syndrome and neurofibromatosis
What are 3 main risk factors for leukemia
Answer- radiation (equivalent to 2 to 3 CTs), toxin /household pesticide
exposure in utero/early childhood.
Acute Leukemia: ALL or AML cancer and symptoms/PE findings
Answer- 2 types: Acute Lymphoblastic Leukemia or Acute Xylogenous
Leukemia.
BLASTs on peripheral smear/bone aspiration in both ALL and AML.
AML also presents with
Auer rods on peripheral smear.
Acute leukemia can also present with leukopenia, combined with anemia
or thrombocytopenia
Children: fever, lethargy, bleeding, potentially spinal or long bone pain.
enlarged spleen, liver, lymphadenopathy.
, Adults (typically young): fever, fatigue, wt. loss. May have anemia
related symptoms (chest pain, SOB)
Chronic Leukemia
Presents in adulthood. predominant cell is mature but does not function
normally, CML (chronic xylogenous leukemia) and CLL (chronic
lymphocytic leukemia)
Look for hepatosplenomegaly and splenomegaly.; some adults are
asymptomatic. WBCs 20,000 to 100,000
Which type of leukemia presents with the Philadelphia chromosome
(BCR-ABL1 fusion gene)?
Chronic xylogenous leukemia
Which type of leukemia is most likely to present in older adults >/=
65y/o?
CLL (chronic lymphocytic leukemia)
In suspected leukemia, what lab work other than CBC should you
obtain?